| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the apramycin-4959 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| AK1 | adenylate kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASPH | aspartate beta-hydroxylase |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| BEX1 | brain expressed, X-linked 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CABIN1 | calcineurin binding protein 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CD82 | CD82 molecule |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNTN1 | contactin 1 |
| COL10A1 | collagen, type X, alpha 1 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DUSP9 | dual specificity phosphatase 9 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EMP3 | epithelial membrane protein 3 |
| FLJ11292 | |
| FMO5 | flavin containing monooxygenase 5 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FYB | FYN binding protein |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLP1R | glucagon-like peptide 1 receptor |
| HGD | homogentisate 1,2-dioxygenase |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HMOX1 | heme oxygenase 1 |
| HOXB5 | homeobox B5 |
| IDS | iduronate 2-sulfatase |
| IDUA | iduronidase, alpha-L- |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL6ST | interleukin 6 signal transducer |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ISL1 | ISL LIM homeobox 1 |
| JAK3 | Janus kinase 3 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KRT85 | keratin 85, type II |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMF2 | lipase maturation factor 2 |
| MCOLN1 | mucolipin 1 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| NEUROD1 | neuronal differentiation 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOP16 | NOP16 nucleolar protein |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRF1 | perforin 1 (pore forming protein) |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTX3 | pentraxin 3, long |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RBM5 | RNA binding motif protein 5 |
| RHBDL1 | rhomboid, veinlet-like 1 (Drosophila) |
| RUNX1 | runt-related transcription factor 1 |
| SHOX2 | short stature homeobox 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNTA1 | syntrophin, alpha 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STEAP4 | STEAP family member 4 |
| STON1 | stonin 1 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| UPK2 | uroplakin 2 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF446 | zinc finger protein 446 |
| ZNF484 | zinc finger protein 484 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| AES | amino-terminal enhancer of split |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATXN2 | ataxin 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CBX8 | chromobox homolog 8 |
| CCDC186 | coiled-coil domain containing 186 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CERK | ceramide kinase |
| COMMD9 | COMM domain containing 9 |
| CORT | cortistatin |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| EFNA3 | ephrin-A3 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FAM63A | family with sequence similarity 63, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC10 | homeobox C10 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IPO8 | importin 8 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGA10 | integrin, alpha 10 |
| JMJD4 | jumonji domain containing 4 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAMLD1 | mastermind-like domain containing 1 |
| METTL16 | methyltransferase like 16 |
| MICALL2 | MICAL-like 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NPY1R | neuropeptide Y receptor Y1 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLA2G3 | phospholipase A2, group III |
| PLCD1 | phospholipase C, delta 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PODXL | podocalyxin-like |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPGRIP1L | RPGRIP1-like |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RUNDC3B | RUN domain containing 3B |
| S100A4 | S100 calcium binding protein A4 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| STRN | striatin, calmodulin binding protein |
| STX1A | syntaxin 1A (brain) |
| SUSD4 | sushi domain containing 4 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK3B | uroplakin 3B |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF219 | zinc finger protein 219 |
| ZNF250 | zinc finger protein 250 |
| ZNF329 | zinc finger protein 329 |
| ZNF639 | zinc finger protein 639 |
| ZNF669 | zinc finger protein 669 |
| ZNF813 | zinc finger protein 813 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |