| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the apramycin-6614 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT11 | acyl-CoA thioesterase 11 |
| ACPP | acid phosphatase, prostate |
| ADGRB3 | adhesion G protein-coupled receptor B3 |
| ADGRD2 | adhesion G protein-coupled receptor D2 |
| ADORA1 | adenosine A1 receptor |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AIM2 | absent in melanoma 2 |
| ANK1 | ankyrin 1, erythrocytic |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| ATXN2L | ataxin 2-like |
| BCL2 | B-cell CLL/lymphoma 2 |
| BMP2 | bone morphogenetic protein 2 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC181 | coiled-coil domain containing 181 |
| CD209 | CD209 molecule |
| CD22 | CD22 molecule |
| CD53 | CD53 molecule |
| CDC42 | cell division cycle 42 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COMMD4 | COMM domain containing 4 |
| CPNE7 | copine VII |
| CRISP1 | cysteine-rich secretory protein 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CRP | C-reactive protein, pentraxin-related |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYTH1 | cytohesin 1 |
| DAPK2 | death-associated protein kinase 2 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DOK5 | docking protein 5 |
| ECE2 | endothelin converting enzyme 2 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
| GLI1 | GLI family zinc finger 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GUCA1B | guanylate cyclase activator 1B (retina) |
| HSD3B1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| IGL | immunoglobulin lambda locus |
| ING2 | inhibitor of growth family, member 2 |
| IZUMO4 | IZUMO family member 4 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIR2DL4 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 |
| KLHL25 | kelch-like family member 25 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOX | lysyl oxidase |
| MATN1 | matrilin 1, cartilage matrix protein |
| MEP1B | meprin A, beta |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MT3 | metallothionein 3 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NDNF | neuron-derived neurotrophic factor |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| NPY5R | neuropeptide Y receptor Y5 |
| PALM | paralemmin |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAC4 | placenta-specific 4 |
| PLK4 | polo-like kinase 4 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PROX1 | prospero homeobox 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 |
| RAB3B | RAB3B, member RAS oncogene family |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SDHD | succinate dehydrogenase complex, subunit D, integral membrane protein |
| SH3GL3 | SH3-domain GRB2-like 3 |
| SLA | Src-like-adaptor |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC13A3 | solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SOX10 | SRY (sex determining region Y)-box 10 |
| SOX2 | SRY (sex determining region Y)-box 2 |
| SPATA6 | spermatogenesis associated 6 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STRA6 | stimulated by retinoic acid 6 |
| TACR1 | tachykinin receptor 1 |
| TBCD | tubulin folding cofactor D |
| TRD | T cell receptor delta locus |
| TRIM29 | tripartite motif containing 29 |
| TRO | trophinin |
| VWA5A | von Willebrand factor A domain containing 5A |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALS2CL | ALS2 C-terminal like |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BRCA2 | breast cancer 2, early onset |
| CAPN15 | calpain 15 |
| CASZ1 | castor zinc finger 1 |
| CBX4 | chromobox homolog 4 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CEP85 | centrosomal protein 85kDa |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| DDX56 | DEAD (Asp-Glu-Ala-Asp) box helicase 56 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM53B | family with sequence similarity 53, member B |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GBX2 | gastrulation brain homeobox 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GTPBP2 | GTP binding protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HSPA1L | heat shock 70kDa protein 1-like |
| IL4R | interleukin 4 receptor |
| IL7 | interleukin 7 |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| KIAA1462 | KIAA1462 |
| KLHL28 | kelch-like family member 28 |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMC3 | laminin, gamma 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LMO7 | LIM domain 7 |
| LOC100127972 | uncharacterized LOC100127972 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEA6 | melanoma antigen family A6 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MCC | mutated in colorectal cancers |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MLYCD | malonyl-CoA decarboxylase |
| MYH9 | myosin, heavy chain 9, non-muscle |
| MYO1D | myosin ID |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PC | pyruvate carboxylase |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PLXNB3 | plexin B3 |
| POLL | polymerase (DNA directed), lambda |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRR7 | proline rich 7 (synaptic) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAI2 | retinoic acid induced 2 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SETBP1 | SET binding protein 1 |
| SIX3 | SIX homeobox 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPAG7 | sperm associated antigen 7 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| TAOK1 | TAO kinase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| TXLNG | taxilin gamma |
| ULBP2 | UL16 binding protein 2 |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR4 | WD repeat domain 4 |
| WDR62 | WD repeat domain 62 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF446 | zinc finger protein 446 |
| ZNF551 | zinc finger protein 551 |
| ZNF675 | zinc finger protein 675 |
| ZNF747 | zinc finger protein 747 |
