| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the apramycin-7334 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARSB | arylsulfatase B |
| ATG3 | autophagy related 3 |
| ATP9A | ATPase, class II, type 9A |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CSF1R | colony stimulating factor 1 receptor |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOC2A | double C2-like domains, alpha |
| EFCAB11 | EF-hand calcium binding domain 11 |
| EFNA3 | ephrin-A3 |
| EHD2 | EH-domain containing 2 |
| EXO5 | exonuclease 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM120C | family with sequence similarity 120C |
| FAM65A | family with sequence similarity 65, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FSCN1 | fascin actin-bundling protein 1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HBS1L | HBS1-like translational GTPase |
| HIC2 | hypermethylated in cancer 2 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXC8 | homeobox C8 |
| IGL | immunoglobulin lambda locus |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIF13A | kinesin family member 13A |
| KLHL20 | kelch-like family member 20 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| MAMLD1 | mastermind-like domain containing 1 |
| MID1 | midline 1 |
| MIIP | migration and invasion inhibitory protein |
| MUC1 | mucin 1, cell surface associated |
| NAG18 | NAG18 mRNA |
| NCKAP1 | NCK-associated protein 1 |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NF1 | neurofibromin 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PDE8B | phosphodiesterase 8B |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PML | promyelocytic leukemia |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PTK6 | protein tyrosine kinase 6 |
| PXN | paxillin |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RECQL5 | RecQ protein-like 5 |
| RGS12 | regulator of G-protein signaling 12 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIF1 | replication timing regulatory factor 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SEC24D | SEC24 family member D |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERHL2 | serine hydrolase-like 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TBKBP1 | TBK1 binding protein 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TOP3B | topoisomerase (DNA) III beta |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM3 | tripartite motif containing 3 |
| TSPAN9 | tetraspanin 9 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UBXN6 | UBX domain protein 6 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VDAC3 | voltage-dependent anion channel 3 |
| VEGFA | vascular endothelial growth factor A |
| VN1R1 | vomeronasal 1 receptor 1 |
| YY2 | YY2 transcription factor |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFHX4 | zinc finger homeobox 4 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF442 | zinc finger protein 442 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| BCORL1 | BCL6 corepressor-like 1 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CAPN15 | calpain 15 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNL2 | cyclin L2 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CIDEC | cell death-inducing DFFA-like effector c |
| COPS7B | COP9 signalosome subunit 7B |
| CTAGE9 | CTAGE family, member 9 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EAF2 | ELL associated factor 2 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUZ | fuzzy planar cell polarity protein |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPATCH2L | G patch domain containing 2-like |
| GPC3 | glypican 3 |
| GPR27 | G protein-coupled receptor 27 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4F | histone cluster 1, H4f |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF1 | interferon regulatory factor 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIAA0556 | KIAA0556 |
| KIF13B | kinesin family member 13B |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL12 | kelch-like family member 12 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LAMB3 | laminin, beta 3 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBTD1 | mbt domain containing 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MED4 | mediator complex subunit 4 |
| MGC12488 | |
| MID1IP1 | MID1 interacting protein 1 |
| NRSN2 | neurensin 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OLFML2A | olfactomedin-like 2A |
| OTUD3 | OTU deubiquitinase 3 |
| PCDHB3 | protocadherin beta 3 |
| PCDHB8 | protocadherin beta 8 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PODXL2 | podocalyxin-like 2 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNF170 | ring finger protein 170 |
| RNF25 | ring finger protein 25 |
| RNF31 | ring finger protein 31 |
| SCMH1 | sex comb on midleg homolog 1 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SPIDR | scaffolding protein involved in DNA repair |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STX1A | syntaxin 1A (brain) |
| SYT17 | synaptotagmin XVII |
| TAOK1 | TAO kinase 1 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAIP | TRAF interacting protein |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| TWF2 | twinfilin actin binding protein 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WWC2 | WW and C2 domain containing 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF227 | zinc finger protein 227 |
| ZNF276 | zinc finger protein 276 |
| ZNF580 | zinc finger protein 580 |
| ZNF747 | zinc finger protein 747 |
| ZNF816 | zinc finger protein 816 |
