| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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193 genes differentially expressed following the arcaine-3010 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANKRD53 | ankyrin repeat domain 53 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ATG10 | autophagy related 10 |
| ATP9A | ATPase, class II, type 9A |
| ATXN2L | ataxin 2-like |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| BTD | biotinidase |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CCL21 | chemokine (C-C motif) ligand 21 |
| CCNK | cyclin K |
| CD300C | CD300c molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CFP | complement factor properdin |
| CHGB | chromogranin B |
| CHMP6 | charged multivesicular body protein 6 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 |
| DOK3 | docking protein 3 |
| DUSP4 | dual specificity phosphatase 4 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| FAM110B | family with sequence similarity 110, member B |
| FDPS | farnesyl diphosphate synthase |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GYG2 | glycogenin 2 |
| HIST1H2BO | histone cluster 1, H2bo |
| HOXC11 | homeobox C11 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IL36G | interleukin 36, gamma |
| INA | internexin neuronal intermediate filament protein, alpha |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KDSR | 3-ketodihydrosphingosine reductase |
| KIAA0509 | uncharacterized LOC57242 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT23 | keratin 23, type I |
| LAMB2 | laminin, beta 2 (laminin S) |
| LIMD1 | LIM domains containing 1 |
| LIMD2 | LIM domain containing 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MUC13 | mucin 13, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL10 | myosin, light chain 10, regulatory |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NCAM1 | neural cell adhesion molecule 1 |
| NUDCD3 | NudC domain containing 3 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OCM2 | oncomodulin 2 |
| ONECUT1 | one cut homeobox 1 |
| PCDH11X | protocadherin 11 X-linked |
| PDLIM4 | PDZ and LIM domain 4 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| RARA | retinoic acid receptor, alpha |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RIF1 | replication timing regulatory factor 1 |
| ROR1 | receptor tyrosine kinase-like orphan receptor 1 |
| RPL10L | ribosomal protein L10-like |
| RPL7 | ribosomal protein L7 |
| RRBP1 | ribosome binding protein 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal |
| SRRM2 | serine/arginine repetitive matrix 2 |
| SSH3 | slingshot protein phosphatase 3 |
| STRN | striatin, calmodulin binding protein |
| SYNM | synemin, intermediate filament protein |
| SYNPO | synaptopodin |
| TACR1 | tachykinin receptor 1 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TEX13A | testis expressed 13A |
| THBS3 | thrombospondin 3 |
| TMEM242 | transmembrane protein 242 |
| TMOD1 | tropomodulin 1 |
| TRIM49 | tripartite motif containing 49 |
| TRPC2 | transient receptor potential cation channel, subfamily C, member 2, pseudogene |
| TSKU | tsukushi, small leucine rich proteoglycan |
| USP53 | ubiquitin specific peptidase 53 |
| VPS16 | vacuolar protein sorting 16 homolog (S. cerevisiae) |
| VSNL1 | visinin-like 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AEN | apoptosis enhancing nuclease |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALKBH1 | alkB, alkylation repair homolog 1 (E. coli) |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BTBD18 | BTB (POZ) domain containing 18 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| C8A | complement component 8, alpha polypeptide |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CCDC15 | coiled-coil domain containing 15 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP295 | centrosomal protein 295kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CTSD | cathepsin D |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EBF2 | early B-cell factor 2 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERCC6 | excision repair cross-complementation group 6 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM188A | family with sequence similarity 188, member A |
| FBRS | fibrosin |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FNBP1L | formin binding protein 1-like |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HARS2 | histidyl-tRNA synthetase 2, mitochondrial |
| HDAC7 | histone deacetylase 7 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGH | immunoglobulin heavy locus |
| JMJD4 | jumonji domain containing 4 |
| KIAA0232 | KIAA0232 |
| KIAA0319L | KIAA0319-like |
| KLHL36 | kelch-like family member 36 |
| KPTN | kaptin (actin binding protein) |
| LRRC42 | leucine rich repeat containing 42 |
| LTC4S | leukotriene C4 synthase |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NME8 | NME/NM23 family member 8 |
| NMUR1 | neuromedin U receptor 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OCLN | occludin |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PITX2 | paired-like homeodomain 2 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMCH | pro-melanin-concentrating hormone |
| POMZP3 | POM121 and ZP3 fusion |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RWDD2A | RWD domain containing 2A |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TRABD | TraB domain containing |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM68 | tripartite motif containing 68 |
| TTPAL | tocopherol (alpha) transfer protein-like |
| TWIST1 | twist family bHLH transcription factor 1 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF32 | zinc finger protein 32 |
| ZNF324 | zinc finger protein 324 |
| ZNF480 | zinc finger protein 480 |
| ZNF74 | zinc finger protein 74 |
| ZNF81 | zinc finger protein 81 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |