arcaine-3010 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the arcaine-3010 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM28 ADAM metallopeptidase domain 28
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ALDOB aldolase B, fructose-bisphosphate
ANKRD53 ankyrin repeat domain 53
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATG10 autophagy related 10
ATP9A ATPase, class II, type 9A
ATXN2L ataxin 2-like
BLZF1 basic leucine zipper nuclear factor 1
BTD biotinidase
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL21 chemokine (C-C motif) ligand 21
CCNK cyclin K
CD300C CD300c molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CFP complement factor properdin
CHGB chromogranin B
CHMP6 charged multivesicular body protein 6
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRABP2 cellular retinoic acid binding protein 2
CSPG4 chondroitin sulfate proteoglycan 4
CXCL3 chemokine (C-X-C motif) ligand 3
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DOK3 docking protein 3
DUSP4 dual specificity phosphatase 4
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM110B family with sequence similarity 110, member B
FDPS farnesyl diphosphate synthase
FXYD3 FXYD domain containing ion transport regulator 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK5 G protein-coupled receptor kinase 5
GYG2 glycogenin 2
HIST1H2BO histone cluster 1, H2bo
HOXC11 homeobox C11
IGFBP5 insulin-like growth factor binding protein 5
IL36G interleukin 36, gamma
INA internexin neuronal intermediate filament protein, alpha
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1
KDSR 3-ketodihydrosphingosine reductase
KIAA0509 uncharacterized LOC57242
KIF25-AS1 KIF25 antisense RNA 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KRT23 keratin 23, type I
LAMB2 laminin, beta 2 (laminin S)
LIMD1 LIM domains containing 1
LIMD2 LIM domain containing 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD1 leiomodin 1 (smooth muscle)
MUC13 mucin 13, cell surface associated
MYH14 myosin, heavy chain 14, non-muscle
MYL10 myosin, light chain 10, regulatory
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCAM1 neural cell adhesion molecule 1
NUDCD3 NudC domain containing 3
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OCM2 oncomodulin 2
ONECUT1 one cut homeobox 1
PCDH11X protocadherin 11 X-linked
PDLIM4 PDZ and LIM domain 4
PEX16 peroxisomal biogenesis factor 16
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRELP proline/arginine-rich end leucine-rich repeat protein
RARA retinoic acid receptor, alpha
RASAL1 RAS protein activator like 1 (GAP1 like)
RIF1 replication timing regulatory factor 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPL10L ribosomal protein L10-like
RPL7 ribosomal protein L7
RRBP1 ribosome binding protein 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SRRM2 serine/arginine repetitive matrix 2
SSH3 slingshot protein phosphatase 3
STRN striatin, calmodulin binding protein
SYNM synemin, intermediate filament protein
SYNPO synaptopodin
TACR1 tachykinin receptor 1
TAPT1 transmembrane anterior posterior transformation 1
TEX13A testis expressed 13A
THBS3 thrombospondin 3
TMEM242 transmembrane protein 242
TMOD1 tropomodulin 1
TRIM49 tripartite motif containing 49
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TSKU tsukushi, small leucine rich proteoglycan
USP53 ubiquitin specific peptidase 53
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VSNL1 visinin-like 1
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
AEN apoptosis enhancing nuclease
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
BACE1 beta-site APP-cleaving enzyme 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BTBD18 BTB (POZ) domain containing 18
C11ORF21 chromosome 11 open reading frame 21
C3ORF18 chromosome 3 open reading frame 18
C8A complement component 8, alpha polypeptide
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCDC15 coiled-coil domain containing 15
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CDR2L cerebellar degeneration-related protein 2-like
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CLCN5 chloride channel, voltage-sensitive 5
CTSD cathepsin D
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAL4 dynein, axonemal, light chain 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EBF2 early B-cell factor 2
ECI2 enoyl-CoA delta isomerase 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERCC6 excision repair cross-complementation group 6
ERO1LB ERO1-like beta (S. cerevisiae)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM188A family with sequence similarity 188, member A
FBRS fibrosin
FBXL7 F-box and leucine-rich repeat protein 7
FNBP1L formin binding protein 1-like
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GAMT guanidinoacetate N-methyltransferase
GBP2 guanylate binding protein 2, interferon-inducible
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HARS2 histidyl-tRNA synthetase 2, mitochondrial
HDAC7 histone deacetylase 7
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGH immunoglobulin heavy locus
JMJD4 jumonji domain containing 4
KIAA0232 KIAA0232
KIAA0319L KIAA0319-like
KLHL36 kelch-like family member 36
KPTN kaptin (actin binding protein)
LRRC42 leucine rich repeat containing 42
LTC4S leukotriene C4 synthase
LZTR1 leucine-zipper-like transcription regulator 1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBD5 methyl-CpG binding domain protein 5
MRPS18C mitochondrial ribosomal protein S18C
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NME8 NME/NM23 family member 8
NMUR1 neuromedin U receptor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OCLN occludin
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PITX2 paired-like homeodomain 2
PKD2L2 polycystic kidney disease 2-like 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMCH pro-melanin-concentrating hormone
POMZP3 POM121 and ZP3 fusion
PTCD2 pentatricopeptide repeat domain 2
RFPL1S RFPL1 antisense RNA 1
RFTN1 raftlin, lipid raft linker 1
RWDD2A RWD domain containing 2A
SIAH2 siah E3 ubiquitin protein ligase 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC16A4 solute carrier family 16, member 4
SLITRK5 SLIT and NTRK-like family, member 5
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TNNT1 troponin T type 1 (skeletal, slow)
TRABD TraB domain containing
TRAPPC6A trafficking protein particle complex 6A
TRIM68 tripartite motif containing 68
TTPAL tocopherol (alpha) transfer protein-like
TWIST1 twist family bHLH transcription factor 1
ZBTB25 zinc finger and BTB domain containing 25
ZNF32 zinc finger protein 32
ZNF324 zinc finger protein 324
ZNF480 zinc finger protein 480
ZNF74 zinc finger protein 74
ZNF81 zinc finger protein 81
ZSCAN31 zinc finger and SCAN domain containing 31