| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the arcaine-3349 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| APOC1 | apolipoprotein C-I |
| AQP3 | aquaporin 3 (Gill blood group) |
| AR | androgen receptor |
| B9D2 | B9 protein domain 2 |
| BTD | biotinidase |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCDC64 | coiled-coil domain containing 64 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHN2 | chimerin 2 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CLSTN2 | calsyntenin 2 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DEAF1 | DEAF1 transcription factor |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| ELL | elongation factor RNA polymerase II |
| ESRRA | estrogen-related receptor alpha |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FAM149A | family with sequence similarity 149, member A |
| FAM198B | family with sequence similarity 198, member B |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FGF18 | fibroblast growth factor 18 |
| FHL1 | four and a half LIM domains 1 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPR135 | G protein-coupled receptor 135 |
| GSN | gelsolin |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ITM2C | integral membrane protein 2C |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MAPK14 | mitogen-activated protein kinase 14 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MTMR1 | myotubularin related protein 1 |
| MYF5 | myogenic factor 5 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDRG2 | NDRG family member 2 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NEUROD4 | neuronal differentiation 4 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NME5 | NME/NM23 family member 5 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| NUP50 | nucleoporin 50kDa |
| PCDHB13 | protocadherin beta 13 |
| PCDHGA3 | protocadherin gamma subfamily A, 3 |
| PCDHGA8 | protocadherin gamma subfamily A, 8 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PLLP | plasmolipin |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PQLC2 | PQ loop repeat containing 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRKCI | protein kinase C, iota |
| PRLH | prolactin releasing hormone |
| PRLR | prolactin receptor |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| PVRL3 | poliovirus receptor-related 3 |
| RASA3 | RAS p21 protein activator 3 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RND1 | Rho family GTPase 1 |
| S100A8 | S100 calcium binding protein A8 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SP1 | Sp1 transcription factor |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STK17B | serine/threonine kinase 17b |
| STOML1 | stomatin (EPB72)-like 1 |
| TBXA2R | thromboxane A2 receptor |
| TGM2 | transglutaminase 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TMEM259 | transmembrane protein 259 |
| TPMT | thiopurine S-methyltransferase |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| UCN | urocortin |
| USP46 | ubiquitin specific peptidase 46 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZBED4 | zinc finger, BED-type containing 4 |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF639 | zinc finger protein 639 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ACVR2A | activin A receptor, type IIA |
| ADAP2 | ArfGAP with dual PH domains 2 |
| APOC4 | apolipoprotein C-IV |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASPN | asporin |
| BAK1 | BCL2-antagonist/killer 1 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHKB | choline kinase beta |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CISH | cytokine inducible SH2-containing protein |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CTAGE9 | CTAGE family, member 9 |
| CTSK | cathepsin K |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| DAGLA | diacylglycerol lipase, alpha |
| DBF4B | DBF4 zinc finger B |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DOCK4 | dedicator of cytokinesis 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DYSF | dysferlin |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ETNK2 | ethanolamine kinase 2 |
| FAM120C | family with sequence similarity 120C |
| FAM186A | family with sequence similarity 186, member A |
| FAM46C | family with sequence similarity 46, member C |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FLT4 | fms-related tyrosine kinase 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXC8 | homeobox C8 |
| IFT22 | intraflagellar transport 22 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0894 | KIAA0894 protein |
| KIF13B | kinesin family member 13B |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAGEA6 | melanoma antigen family A6 |
| MYOZ3 | myozenin 3 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPTX1 | neuronal pentraxin I |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDE8B | phosphodiesterase 8B |
| PENK | proenkephalin |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| POM121 | POM121 transmembrane nucleoporin |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRSS16 | protease, serine, 16 (thymus) |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RNF43 | ring finger protein 43 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SDC3 | syndecan 3 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SKI | SKI proto-oncogene |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPON2 | spondin 2, extracellular matrix protein |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STX1A | syntaxin 1A (brain) |
| SYNC | syncoilin, intermediate filament protein |
| TCTN2 | tectonic family member 2 |
| THBS3 | thrombospondin 3 |
| THRB | thyroid hormone receptor, beta |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM212 | transmembrane protein 212 |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UNC119 | unc-119 homolog (C. elegans) |
| UPK3B | uroplakin 3B |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| VLDLR | very low density lipoprotein receptor |
| ZNF211 | zinc finger protein 211 |
| ZNF250 | zinc finger protein 250 |
| ZNF286A | zinc finger protein 286A |
| ZNF358 | zinc finger protein 358 |
| ZNF665 | zinc finger protein 665 |
