| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the arcaine-4974 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| APOM | apolipoprotein M |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| AUTS2 | autism susceptibility candidate 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| CAPN9 | calpain 9 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD6 | CD6 molecule |
| CD82 | CD82 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CENPO | centromere protein O |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNTN1 | contactin 1 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DMPK | dystrophia myotonica-protein kinase |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EML2 | echinoderm microtubule associated protein like 2 |
| EPHA1 | EPH receptor A1 |
| FAM134B | family with sequence similarity 134, member B |
| FBXO41 | F-box protein 41 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR137 | G protein-coupled receptor 137 |
| GPR27 | G protein-coupled receptor 27 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HEATR1 | HEAT repeat containing 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIRA | histone cell cycle regulator |
| HMOX1 | heme oxygenase 1 |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| HOMER3 | homer scaffolding protein 3 |
| HOXB2 | homeobox B2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ING2 | inhibitor of growth family, member 2 |
| ING4 | inhibitor of growth family, member 4 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0319L | KIAA0319-like |
| KIAA0368 | KIAA0368 |
| LENEP | lens epithelial protein |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MINK1 | misshapen-like kinase 1 |
| MMP3 | matrix metallopeptidase 3 |
| MTM1 | myotubularin 1 |
| MUC3A | mucin 3A, cell surface associated |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NF2 | neurofibromin 2 (merlin) |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAPOLA | poly(A) polymerase alpha |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU4F2 | POU class 4 homeobox 2 |
| PROL1 | proline rich, lacrimal 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RARG | retinoic acid receptor, gamma |
| RBM19 | RNA binding motif protein 19 |
| RPLP2 | ribosomal protein, large, P2 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SIRT3 | sirtuin 3 |
| SLC35D1 | solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNTA1 | syntrophin, alpha 1 |
| SPHK2 | sphingosine kinase 2 |
| STON1 | stonin 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TLE3 | transducin-like enhancer of split 3 |
| TLR5 | toll-like receptor 5 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TUBA4B | tubulin, alpha 4b |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFHX4 | zinc finger homeobox 4 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF493 | zinc finger protein 493 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARL15 | ADP-ribosylation factor-like 15 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL2A1 | BCL2-related protein A1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C5AR2 | complement component 5a receptor 2 |
| CA11 | carbonic anhydrase XI |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CASZ1 | castor zinc finger 1 |
| CCDC132 | coiled-coil domain containing 132 |
| CD34 | CD34 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHPF | chondroitin polymerizing factor |
| CLSTN2 | calsyntenin 2 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYSF | dysferlin |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM155A | family with sequence similarity 155, member A |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FILIP1L | filamin A interacting protein 1-like |
| FOXN2 | forkhead box N2 |
| FRK | fyn-related Src family tyrosine kinase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GID4 | GID complex subunit 4 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GOLGA8B | golgin A8 family, member B |
| GPR157 | G protein-coupled receptor 157 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BO | histone cluster 1, H2bo |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXA5 | homeobox A5 |
| HOXC5 | homeobox C5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0754 | KIAA0754 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MVP | major vault protein |
| MYF5 | myogenic factor 5 |
| NES | nestin |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDE8B | phosphodiesterase 8B |
| PITX2 | paired-like homeodomain 2 |
| PLCD1 | phospholipase C, delta 1 |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| PRPH | peripherin |
| RAB30 | RAB30, member RAS oncogene family |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF39 | ring finger protein 39 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SKI | SKI proto-oncogene |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D19 | TBC1 domain family, member 19 |
| TCTA | T-cell leukemia translocation altered |
| TESC | tescalcin |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TH | tyrosine hydroxylase |
| TIGD6 | tigger transposable element derived 6 |
| TMC5 | transmembrane channel-like 5 |
| TMEM121 | transmembrane protein 121 |
| TMEM212 | transmembrane protein 212 |
| TOM1 | target of myb1 (chicken) |
| TRAIP | TRAF interacting protein |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UBXN6 | UBX domain protein 6 |
| UNC119 | unc-119 homolog (C. elegans) |
| VEGFC | vascular endothelial growth factor C |
| ZNF10 | zinc finger protein 10 |
| ZNF16 | zinc finger protein 16 |
| ZNF304 | zinc finger protein 304 |
| ZNF516 | zinc finger protein 516 |
| ZNF551 | zinc finger protein 551 |
| ZNF571 | zinc finger protein 571 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |