arcaine-6629 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the arcaine-6629 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACVR1B activin A receptor, type IB
ANP32A-IT1 ANP32A intronic transcript 1
APAF1 apoptotic peptidase activating factor 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP44 Rho GTPase activating protein 44
ART1 ADP-ribosyltransferase 1
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATF7IP activating transcription factor 7 interacting protein
BAAT bile acid CoA:amino acid N-acyltransferase
BCAP29 B-cell receptor-associated protein 29
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMPR1B bone morphogenetic protein receptor, type IB
C10ORF10 chromosome 10 open reading frame 10
C1ORF116 chromosome 1 open reading frame 116
C1ORF21 chromosome 1 open reading frame 21
C3AR1 complement component 3a receptor 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CCDC71 coiled-coil domain containing 71
CCL11 chemokine (C-C motif) ligand 11
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNOT4 CCR4-NOT transcription complex, subunit 4
CPNE7 copine VII
CREBZF CREB/ATF bZIP transcription factor
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CTSS cathepsin S
DCTN2 dynactin 2 (p50)
DDO D-aspartate oxidase
DOCK10 dedicator of cytokinesis 10
E2F5 E2F transcription factor 5, p130-binding
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM46C family with sequence similarity 46, member C
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FRMD4B FERM domain containing 4B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GSK3A glycogen synthase kinase 3 alpha
HIST1H2BO histone cluster 1, H2bo
ICOSLG inducible T-cell co-stimulator ligand
ING2 inhibitor of growth family, member 2
IRAK4 interleukin-1 receptor-associated kinase 4
KCTD13 potassium channel tetramerization domain containing 13
KCTD17 potassium channel tetramerization domain containing 17
LCAT lecithin-cholesterol acyltransferase
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAGEA5 melanoma antigen family A5
MAP2K5 mitogen-activated protein kinase kinase 5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MMP25 matrix metallopeptidase 25
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MST1 macrophage stimulating 1
NFX1 nuclear transcription factor, X-box binding 1
NNMT nicotinamide N-methyltransferase
OGFR opioid growth factor receptor
PALM paralemmin
PBX2 pre-B-cell leukemia homeobox 2
PCDHB1 protocadherin beta 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDPN podoplanin
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHLDB1 pleckstrin homology-like domain, family B, member 1
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2R1 phospholipase A2 receptor 1, 180kDa
PODNL1 podocan-like 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RABGAP1 RAB GTPase activating protein 1
RAP2B RAP2B, member of RAS oncogene family
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL35A ribosomal protein L35a
RPS28 ribosomal protein S28
SH2D1A SH2 domain containing 1A
SLMO1 slowmo homolog 1 (Drosophila)
SNN stannin
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA5L1 spermatogenesis associated 5-like 1
STAB2 stabilin 2
STK3 serine/threonine kinase 3
STS steroid sulfatase (microsomal), isozyme S
TBX2 T-box 2
TLK1 tousled-like kinase 1
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TTC12 tetratricopeptide repeat domain 12
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WWOX WW domain containing oxidoreductase
YTHDC2 YTH domain containing 2
ZNF391 zinc finger protein 391

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANXA2P1 annexin A2 pseudogene 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD3A ATPase family, AAA domain containing 3A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AXIN1 axin 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
CCDC85C coiled-coil domain containing 85C
CCNJL cyclin J-like
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD79B CD79b molecule, immunoglobulin-associated beta
CENPO centromere protein O
CLASRP CLK4-associating serine/arginine rich protein
CLDN1 claudin 1
CNPY3 canopy FGF signaling regulator 3
COL21A1 collagen, type XXI, alpha 1
COL9A2 collagen, type IX, alpha 2
CST1 cystatin SN
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DBF4B DBF4 zinc finger B
DDN dendrin
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNAH17 dynein, axonemal, heavy chain 17
FBXO40 F-box protein 40
FUZ fuzzy planar cell polarity protein
GLS2 glutaminase 2 (liver, mitochondrial)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR19 G protein-coupled receptor 19
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H2BN histone cluster 1, H2bn
HIST1H3A histone cluster 1, H3a
HIST1H3G histone cluster 1, H3g
IFT46 intraflagellar transport 46
IFT54 intraflagellar transport 54
INO80D INO80 complex subunit D
IPO8 importin 8
IQSEC2 IQ motif and Sec7 domain 2
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
KIAA1456 KIAA1456
KIRREL kin of IRRE like (Drosophila)
KLHL36 kelch-like family member 36
KRT31 keratin 31, type I
KRT8P12 keratin 8 pseudogene 12
LINC00341 long intergenic non-protein coding RNA 341
LMTK1 lemur tail kinase 1
MGP matrix Gla protein
MMP10 matrix metallopeptidase 10
MYL10 myosin, light chain 10, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDRG4 NDRG family member 4
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NT5M 5',3'-nucleotidase, mitochondrial
ONECUT2 one cut homeobox 2
OSBP2 oxysterol binding protein 2
OSR2 odd-skipped related transciption factor 2
PDZK1 PDZ domain containing 1
PLAC8 placenta-specific 8
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPT2 palmitoyl-protein thioesterase 2
PRR14L proline rich 14-like
PTDSS2 phosphatidylserine synthase 2
PWAR5 Prader Willi/Angelman region RNA 5
REM1 RAS (RAD and GEM)-like GTP-binding 1
RUNX1-IT1 RUNX1 intronic transcript 1
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIRT6 sirtuin 6
SIX3 SIX homeobox 3
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
STK16 serine/threonine kinase 16
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAS2R10 taste receptor, type 2, member 10
TBC1D22B TBC1 domain family, member 22B
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN2 tectonic family member 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM51 transmembrane protein 51
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPCN1 two pore segment channel 1
TRIM21 tripartite motif containing 21
TUBA3C tubulin, alpha 3c
USP27X ubiquitin specific peptidase 27, X-linked
WNT7A wingless-type MMTV integration site family, member 7A
ZCWPW1 zinc finger, CW type with PWWP domain 1