| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the arecoline-1303 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| ANKH | ANKH inorganic pyrophosphate transport regulator |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ATXN2L | ataxin 2-like |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BNC2 | basonuclin 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CCND1 | cyclin D1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK20 | cyclin-dependent kinase 20 |
| CENPB | centromere protein B, 80kDa |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| COMT | catechol-O-methyltransferase |
| CREM | cAMP responsive element modulator |
| DACH1 | dachshund family transcription factor 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EGR1 | early growth response 1 |
| EMILIN2 | elastin microfibril interfacer 2 |
| EML3 | echinoderm microtubule associated protein like 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM3A | family with sequence similarity 3, member A |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GMDS | GDP-mannose 4,6-dehydratase |
| GSK3A | glycogen synthase kinase 3 alpha |
| H2AFX | H2A histone family, member X |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HSF1 | heat shock transcription factor 1 |
| ITCH | itchy E3 ubiquitin protein ligase |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KIAA0319L | KIAA0319-like |
| KIAA0754 | KIAA0754 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LOC100287590 | uncharacterized LOC100287590 |
| MAP4 | microtubule-associated protein 4 |
| MEF2D | myocyte enhancer factor 2D |
| METTL7A | methyltransferase like 7A |
| MIIP | migration and invasion inhibitory protein |
| MPZ | myelin protein zero |
| MTA1 | metastasis associated 1 |
| MUC8 | mucin 8 |
| NCLN | nicalin |
| NEFH | neurofilament, heavy polypeptide |
| NPDC1 | neural proliferation, differentiation and control, 1 |
| NPRL3 | nitrogen permease regulator-like 3 (S. cerevisiae) |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OBSL1 | obscurin-like 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PHF1 | PHD finger protein 1 |
| PMP22 | peripheral myelin protein 22 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PSKH1 | protein serine kinase H1 |
| PTAFR | platelet-activating factor receptor |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTCH1 | patched 1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RET | ret proto-oncogene |
| RHOD | ras homolog family member D |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCAMP4 | secretory carrier membrane protein 4 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SIN3B | SIN3 transcription regulator family member B |
| SIRT5 | sirtuin 5 |
| SKIL | SKI-like proto-oncogene |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SPAG4 | sperm associated antigen 4 |
| SPATA20 | spermatogenesis associated 20 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN32 | tetraspanin 32 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| WDR61 | WD repeat domain 61 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| YIPF2 | Yip1 domain family, member 2 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZNF473 | zinc finger protein 473 |
| ZNF574 | zinc finger protein 574 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKTIP | AKT interacting protein |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit |
| ARG1 | arginase 1 |
| ATG2B | autophagy related 2B |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C5 | complement component 5 |
| CEP170B | centrosomal protein 170B |
| CEP85 | centrosomal protein 85kDa |
| CLDND1 | claudin domain containing 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EFTUD1 | elongation factor Tu GTP binding domain containing 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERCC2 | excision repair cross-complementation group 2 |
| ERCC6L | excision repair cross-complementation group 6-like |
| EXOC5 | exocyst complex component 5 |
| FAM222B | family with sequence similarity 222, member B |
| FCHSD2 | FCH and double SH3 domains 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HCFC2 | host cell factor C2 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFT81 | intraflagellar transport 81 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| ITGB7 | integrin, beta 7 |
| JADE3 | jade family PHD finger 3 |
| KIF1B | kinesin family member 1B |
| KLHL12 | kelch-like family member 12 |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 |
| LMAN1 | lectin, mannose-binding, 1 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRRC42 | leucine rich repeat containing 42 |
| LY96 | lymphocyte antigen 96 |
| MANEA | mannosidase, endo-alpha |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MED9 | mediator complex subunit 9 |
| MX2 | MX dynamin-like GTPase 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NABP2 | nucleic acid binding protein 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PARPBP | PARP1 binding protein |
| PCYOX1 | prenylcysteine oxidase 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF121 | ring finger protein 121 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SLC41A3 | solute carrier family 41, member 3 |
| SLFN12 | schlafen family member 12 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| TCTN2 | tectonic family member 2 |
| TDRD3 | tudor domain containing 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THEM6 | thioesterase superfamily member 6 |
| TLR1 | toll-like receptor 1 |
| TLR4 | toll-like receptor 4 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM230 | transmembrane protein 230 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TRIM22 | tripartite motif containing 22 |
| TRIM26 | tripartite motif containing 26 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUFT1 | tuftelin 1 |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| ZFYVE21 | zinc finger, FYVE domain containing 21 |
| ZNF134 | zinc finger protein 134 |
| ZNF16 | zinc finger protein 16 |
| ZNF227 | zinc finger protein 227 |
| ZNF273 | zinc finger protein 273 |
| ZNF345 | zinc finger protein 345 |
| ZNF557 | zinc finger protein 557 |
| ZNF665 | zinc finger protein 665 |
| ZNF701 | zinc finger protein 701 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF770 | zinc finger protein 770 |
| ZNF83 | zinc finger protein 83 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZW10 | zw10 kinetochore protein |
