| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the arecoline-2657 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 |
| ADORA1 | adenosine A1 receptor |
| ALDOB | aldolase B, fructose-bisphosphate |
| AMPD3 | adenosine monophosphate deaminase 3 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C8B | complement component 8, beta polypeptide |
| CA4 | carbonic anhydrase IV |
| CFHR4 | complement factor H-related 4 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CORO7 | coronin 7 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOC2A | double C2-like domains, alpha |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| ENO3 | enolase 3 (beta, muscle) |
| ETNK2 | ethanolamine kinase 2 |
| FBLN1 | fibulin 1 |
| FGF17 | fibroblast growth factor 17 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| HOXC8 | homeobox C8 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KCNJ4 | potassium channel, inwardly rectifying subfamily J, member 4 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA1456 | KIAA1456 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT17 | keratin 17, type I |
| LECT1 | leukocyte cell derived chemotaxin 1 |
| LENEP | lens epithelial protein |
| LEPR | leptin receptor |
| LIG3 | ligase III, DNA, ATP-dependent |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYO1B | myosin IB |
| NFIB | nuclear factor I/B |
| NOL12 | nucleolar protein 12 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAX8 | paired box 8 |
| PCM1 | pericentriolar material 1 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPARA | peroxisome proliferator-activated receptor alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRKCE | protein kinase C, epsilon |
| RASAL2 | RAS protein activator like 2 |
| RECQL5 | RecQ protein-like 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RRBP1 | ribosome binding protein 1 |
| SAV1 | salvador family WW domain containing protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCARB1 | scavenger receptor class B, member 1 |
| SCLY | selenocysteine lyase |
| SFRP4 | secreted frizzled-related protein 4 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) |
| SPON2 | spondin 2, extracellular matrix protein |
| SSH3 | slingshot protein phosphatase 3 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYT5 | synaptotagmin V |
| TAZ | tafazzin |
| TBC1D2 | TBC1 domain family, member 2 |
| TCP10L | t-complex 10-like |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRIM29 | tripartite motif containing 29 |
| USP12 | ubiquitin specific peptidase 12 |
| VASH2 | vasohibin 2 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WTAP | Wilms tumor 1 associated protein |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF696 | zinc finger protein 696 |
| ZNF79 | zinc finger protein 79 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| AGMAT | agmatine ureohydrolase (agmatinase) |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARMC6 | armadillo repeat containing 6 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD1A | CD1a molecule |
| CD34 | CD34 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLEC16A | C-type lectin domain family 16, member A |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| EFNA3 | ephrin-A3 |
| EMID1 | EMI domain containing 1 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM204A | family with sequence similarity 204, member A |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GATB | glutamyl-tRNA(Gln) amidotransferase, subunit B |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2I | general transcription factor IIi |
| HIST1H2BJ | histone cluster 1, H2bj |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL4R | interleukin 4 receptor |
| ING4 | inhibitor of growth family, member 4 |
| IPO8 | importin 8 |
| KLHL25 | kelch-like family member 25 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PARPBP | PARP1 binding protein |
| PGBD5 | piggyBac transposable element derived 5 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POLL | polymerase (DNA directed), lambda |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| REPS2 | RALBP1 associated Eps domain containing 2 |
| RIN2 | Ras and Rab interactor 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RSG1 | REM2 and RAB-like small GTPase 1 |
| SDC3 | syndecan 3 |
| SECTM1 | secreted and transmembrane 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNAI2 | snail family zinc finger 2 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| STK16 | serine/threonine kinase 16 |
| TCTN1 | tectonic family member 1 |
| TFF2 | trefoil factor 2 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM110 | transmembrane protein 110 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRIM52 | tripartite motif containing 52 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| VAX2 | ventral anterior homeobox 2 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WLS | wntless Wnt ligand secretion mediator |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF329 | zinc finger protein 329 |
| ZNF428 | zinc finger protein 428 |
| ZNF446 | zinc finger protein 446 |
