| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the arecoline-5423 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADCY2 | adenylate cyclase 2 (brain) |
| AHSG | alpha-2-HS-glycoprotein |
| ALS2CL | ALS2 C-terminal like |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ARTN | artemin |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BMP15 | bone morphogenetic protein 15 |
| BMP5 | bone morphogenetic protein 5 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CD80 | CD80 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CFHR2 | complement factor H-related 2 |
| CLMN | calmin (calponin-like, transmembrane) |
| CREBZF | CREB/ATF bZIP transcription factor |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DOCK10 | dedicator of cytokinesis 10 |
| DOCK6 | dedicator of cytokinesis 6 |
| ECE1 | endothelin converting enzyme 1 |
| EMP3 | epithelial membrane protein 3 |
| FECH | ferrochelatase |
| FHL1 | four and a half LIM domains 1 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GCNT4 | glucosaminyl (N-acetyl) transferase 4, core 2 |
| GM2A | GM2 ganglioside activator |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPR137 | G protein-coupled receptor 137 |
| GPR21 | G protein-coupled receptor 21 |
| GPR6 | G protein-coupled receptor 6 |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSPT2 | G1 to S phase transition 2 |
| HDAC7 | histone deacetylase 7 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HIST1H2BM | histone cluster 1, H2bm |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFNA14 | interferon, alpha 14 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| LBP | lipopolysaccharide binding protein |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRRN3 | leucine rich repeat neuronal 3 |
| LYZL6 | lysozyme-like 6 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MEF2D | myocyte enhancer factor 2D |
| MYO1B | myosin IB |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUDT7 | nudix (nucleoside diphosphate linked moiety X)-type motif 7 |
| OSBPL3 | oxysterol binding protein-like 3 |
| PARVA | parvin, alpha |
| PAX8 | paired box 8 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| POFUT1 | protein O-fucosyltransferase 1 |
| POU4F1 | POU class 4 homeobox 1 |
| R3HDM1 | R3H domain containing 1 |
| RAB36 | RAB36, member RAS oncogene family |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RNF122 | ring finger protein 122 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SOCS7 | suppressor of cytokine signaling 7 |
| SUMO1 | small ubiquitin-like modifier 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCEAL2 | transcription elongation factor A (SII)-like 2 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TNPO2 | transportin 2 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D4 | TSC22 domain family, member 4 |
| UPB1 | ureidopropionase, beta |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| VAMP5 | vesicle-associated membrane protein 5 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| ZFP64 | ZFP64 zinc finger protein |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF235 | zinc finger protein 235 |
| ZNF280A | zinc finger protein 280A |
| ZNF324 | zinc finger protein 324 |
| ZSWIM1 | zinc finger, SWIM-type containing 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACP2 | acid phosphatase 2, lysosomal |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARMC4 | armadillo repeat containing 4 |
| BBC3 | BCL2 binding component 3 |
| BLNK | B-cell linker |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBX8 | chromobox homolog 8 |
| CCDC47 | coiled-coil domain containing 47 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CES3 | carboxylesterase 3 |
| CHM | choroideremia (Rab escort protein 1) |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO2A | coronin, actin binding protein, 2A |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP13 | dual specificity phosphatase 13 |
| EDC4 | enhancer of mRNA decapping 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM204A | family with sequence similarity 204, member A |
| FAM212B | family with sequence similarity 212, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GAS2 | growth arrest-specific 2 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRB7 | growth factor receptor-bound protein 7 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HOXC11 | homeobox C11 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFI35 | interferon-induced protein 35 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KIF5C | kinesin family member 5C |
| KLF3 | Kruppel-like factor 3 (basic) |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LMNB1 | lamin B1 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| OSMR | oncostatin M receptor |
| PCDHA6 | protocadherin alpha 6 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PER3 | period circadian clock 3 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PRR4 | proline rich 4 (lacrimal) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB3D | RAB3D, member RAS oncogene family |
| RNF121 | ring finger protein 121 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STK16 | serine/threonine kinase 16 |
| STX1A | syntaxin 1A (brain) |
| TAOK1 | TAO kinase 1 |
| TBX19 | T-box 19 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM209 | transmembrane protein 209 |
| TMEM212 | transmembrane protein 212 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| XYLT2 | xylosyltransferase II |
| ZNF16 | zinc finger protein 16 |
| ZNF205 | zinc finger protein 205 |
| ZNF254 | zinc finger protein 254 |
| ZNF606 | zinc finger protein 606 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
