arf guanyl-nucleotide exchange factor activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase. (Gene Ontology, GO_0005086)
External Link http://amigo.geneontology.org/amigo/term/GO:0005086
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Genes

18 genes performing the arf guanyl-nucleotide exchange factor activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARFGEF3 ARFGEF family member 3
CYTH1 cytohesin 1
CYTH2 cytohesin 2
CYTH3 cytohesin 3
CYTH4 cytohesin 4
FBXO8 F-box protein 8
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
IQSEC1 IQ motif and Sec7 domain 1
IQSEC2 IQ motif and Sec7 domain 2
IQSEC3 IQ motif and Sec7 domain 3
MON2 MON2 homolog (S. cerevisiae)
PSD pleckstrin and Sec7 domain containing
PSD2 pleckstrin and Sec7 domain containing 2
PSD3 pleckstrin and Sec7 domain containing 3
PSD4 pleckstrin and Sec7 domain containing 4
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