arf1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description ADP-ribosylation factor 1|ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 375)
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Genes

38 genes co-occuring with the biological term arf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ADRA2B adrenoceptor alpha 2B
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ARF1 ADP-ribosylation factor 1
ARF3 ADP-ribosylation factor 3
ARF4 ADP-ribosylation factor 4
ARF6 ADP-ribosylation factor 6
ARFIP2 ADP-ribosylation factor interacting protein 2
ARHGAP21 Rho GTPase activating protein 21
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
CHRM3 cholinergic receptor, muscarinic 3
CYFIP1 cytoplasmic FMR1 interacting protein 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
CYTH2 cytohesin 2
EGF epidermal growth factor
FLT1 fms-related tyrosine kinase 1
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GOSR2 golgi SNAP receptor complex member 2
GRB2 growth factor receptor-bound protein 2
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IQSEC3 IQ motif and Sec7 domain 3
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLIN2 perilipin 2
PSD pleckstrin and Sec7 domain containing
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RAB1B RAB1B, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RB1 retinoblastoma 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
VIM vimentin