arrested t cell differentiation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description failure of T cell formation to proceed past a defined stage (Mammalian Phenotype Ontology, MP_0001825)
External Link
Similar Terms
Downloads & Tools


29 gene mutations causing the arrested t cell differentiation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CARM1 coactivator-associated arginine methyltransferase 1
CBX2 chromobox homolog 2
CD1D CD1d molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD83 CD83 molecule
DCLRE1C DNA cross-link repair 1C
GFI1 growth factor independent 1 transcription repressor
GRAP2 GRB2-related adaptor protein 2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL7R interleukin 7 receptor
ITPKB inositol-trisphosphate 3-kinase B
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIG4 ligase IV, DNA, ATP-dependent
MYB v-myb avian myeloblastosis viral oncogene homolog
NCOR1 nuclear receptor corepressor 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTCRA pre T-cell antigen receptor alpha
PTPRC protein tyrosine phosphatase, receptor type, C
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RHOH ras homolog family member H
RPL22 ribosomal protein L22
SATB1 SATB homeobox 1
TCF12 transcription factor 12
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa