artemisinin-1714 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the artemisinin-1714 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOX3 acyl-CoA oxidase 3, pristanoyl
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATR ATR serine/threonine kinase
CALU calumenin
CCSER2 coiled-coil serine-rich protein 2
CD3D CD3d molecule, delta (CD3-TCR complex)
CD9 CD9 molecule
CDK10 cyclin-dependent kinase 10
CEND1 cell cycle exit and neuronal differentiation 1
CIZ1 CDKN1A interacting zinc finger protein 1
CLPTM1 cleft lip and palate associated transmembrane protein 1
CNTFR ciliary neurotrophic factor receptor
COQ4 coenzyme Q4
CRTC1 CREB regulated transcription coactivator 1
CYTH1 cytohesin 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIO2 deiodinase, iodothyronine, type II
DNM2 dynamin 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EHD1 EH-domain containing 1
EPOR erythropoietin receptor
EXOC7 exocyst complex component 7
EXOSC2 exosome component 2
FASTK Fas-activated serine/threonine kinase
FH fumarate hydratase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
HMGB3P1 high mobility group box 3 pseudogene 1
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9)
HOMER1 homer scaffolding protein 1
HTRA1 HtrA serine peptidase 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IMPAD1 inositol monophosphatase domain containing 1
IRF6 interferon regulatory factor 6
KDM7A lysine (K)-specific demethylase 7A
KLF6 Kruppel-like factor 6
LDOC1 leucine zipper, down-regulated in cancer 1
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LMAN1 lectin, mannose-binding, 1
METAP2 methionyl aminopeptidase 2
METTL13 methyltransferase like 13
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MXRA8 matrix-remodelling associated 8
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NBEAL2 neurobeachin-like 2
NDRG2 NDRG family member 2
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NEFH neurofilament, heavy polypeptide
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae)
NPDC1 neural proliferation, differentiation and control, 1
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PAIP1 poly(A) binding protein interacting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PARD3 par-3 family cell polarity regulator
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PKD2L1 polycystic kidney disease 2-like 1
PKN1 protein kinase N1
PLCB2 phospholipase C, beta 2
PLD2 phospholipase D2
PPIEL peptidylprolyl isomerase E-like pseudogene
PREP prolyl endopeptidase
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTBP3 polypyrimidine tract binding protein 3
PTN pleiotrophin
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RORC RAR-related orphan receptor C
RPS2 ribosomal protein S2
SCAF4 SR-related CTD-associated factor 4
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEC23IP SEC23 interacting protein
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SF3B3 splicing factor 3b, subunit 3, 130kDa
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC38A10 solute carrier family 38, member 10
SPIDR scaffolding protein involved in DNA repair
SPRYD7 SPRY domain containing 7
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
ST14 suppression of tumorigenicity 14 (colon carcinoma)
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
SUGP1 SURP and G patch domain containing 1
SZT2 seizure threshold 2 homolog (mouse)
TBC1D30 TBC1 domain family, member 30
TMED1 transmembrane emp24 protein transport domain containing 1
TMEM127 transmembrane protein 127
TNNT1 troponin T type 1 (skeletal, slow)
TNRC6B trinucleotide repeat containing 6B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAPPC12 trafficking protein particle complex 12
TRIB2 tribbles pseudokinase 2
TTLL3 tubulin tyrosine ligase-like family member 3
USP20 ubiquitin specific peptidase 20
USP34 ubiquitin specific peptidase 34
WDHD1 WD repeat and HMG-box DNA binding protein 1
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACP6 acid phosphatase 6, lysophosphatidic
ACTC1 actin, alpha, cardiac muscle 1
ADGRE5 adhesion G protein-coupled receptor E5
ASB13 ankyrin repeat and SOCS box containing 13
ASTE1 asteroid homolog 1 (Drosophila)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCL7C B-cell CLL/lymphoma 7C
BRD9 bromodomain containing 9
C11ORF73 chromosome 11 open reading frame 73
C14ORF159 chromosome 14 open reading frame 159
CAPN15 calpain 15
CER1 cerberus 1, DAN family BMP antagonist
CFAP74 cilia and flagella associated protein 74
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLDN15 claudin 15
CNTD2 cyclin N-terminal domain containing 2
CORO7 coronin 7
CPA2 carboxypeptidase A2 (pancreatic)
CRYL1 crystallin, lambda 1
DOK2 docking protein 2, 56kDa
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
ECT2 epithelial cell transforming 2
EPM2AIP1 EPM2A (laforin) interacting protein 1
ERO1L ERO1-like (S. cerevisiae)
F3 coagulation factor III (thromboplastin, tissue factor)
FBXO5 F-box protein 5
FCHO1 FCH domain only 1
FGL1 fibrinogen-like 1
FOXK2 forkhead box K2
FZD2 frizzled class receptor 2
GALR3 galanin receptor 3
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GSTA4 glutathione S-transferase alpha 4
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AC histone cluster 1, H2ac
HLA-DMB major histocompatibility complex, class II, DM beta
HOOK2 hook microtubule-tethering protein 2
KCTD15 potassium channel tetramerization domain containing 15
KIFC1 kinesin family member C1
LGALS9 lectin, galactoside-binding, soluble, 9
LIMD2 LIM domain containing 2
LMAN2L lectin, mannose-binding 2-like
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAGOHB mago-nashi homolog B (Drosophila)
MBTD1 mbt domain containing 1
MISP mitotic spindle positioning
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTG1 mitochondrial ribosome-associated GTPase 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDC1 NDC1 transmembrane nucleoporin
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OCEL1 occludin/ELL domain containing 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSTM1 osteopetrosis associated transmembrane protein 1
PAK1IP1 PAK1 interacting protein 1
PARG poly (ADP-ribose) glycohydrolase
PCNXL4 pecanex-like 4 (Drosophila)
PFDN1 prefoldin subunit 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G12A phospholipase A2, group XIIA
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLIN3 perilipin 3
PODNL1 podocan-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF11 ring finger protein 11
RNF144A ring finger protein 144A
RNF220 ring finger protein 220
RNF38 ring finger protein 38
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCN10A sodium channel, voltage gated, type X alpha subunit
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX15 sorting nexin 15
SUOX sulfite oxidase
SUSD6 sushi domain containing 6
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TIGAR TP53 induced glycolysis regulatory phosphatase
TMEM110 transmembrane protein 110
TMEM246 transmembrane protein 246
TMEM53 transmembrane protein 53
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TRIP10 thyroid hormone receptor interactor 10
TSPAN32 tetraspanin 32
TTI2 TELO2 interacting protein 2
WDR7 WD repeat domain 7
WRN Werner syndrome, RecQ helicase-like
XAF1 XIAP associated factor 1
XPC xeroderma pigmentosum, complementation group C
ZBTB39 zinc finger and BTB domain containing 39
ZMYM3 zinc finger, MYM-type 3
ZNF189 zinc finger protein 189
ZNF468 zinc finger protein 468