artemisinin-7247 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the artemisinin-7247 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKAP17A A kinase (PRKA) anchor protein 17A
ANKMY1 ankyrin repeat and MYND domain containing 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTN3A1 butyrophilin, subfamily 3, member A1
C17ORF70 chromosome 17 open reading frame 70
C1S complement component 1, s subcomponent
CCNF cyclin F
CD33 CD33 molecule
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP112 centrosomal protein 112kDa
CEP131 centrosomal protein 131kDa
CIDEB cell death-inducing DFFA-like effector b
CIDEC cell death-inducing DFFA-like effector c
CPPED1 calcineurin-like phosphoesterase domain containing 1
DBP D site of albumin promoter (albumin D-box) binding protein
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM13A family with sequence similarity 13, member A
FAM69A family with sequence similarity 69, member A
FLOT2 flotillin 2
GAREM GRB2 associated, regulator of MAPK1
GPR1 G protein-coupled receptor 1
IFI44 interferon-induced protein 44
IFT27 intraflagellar transport 27
IL17RA interleukin 17 receptor A
IL7 interleukin 7
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KDR kinase insert domain receptor
LDAH lipid droplet associated hydrolase
LOC730101 uncharacterized LOC730101
LRRC61 leucine rich repeat containing 61
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYPD1 LY6/PLAUR domain containing 1
MEF2C myocyte enhancer factor 2C
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MN1 meningioma (disrupted in balanced translocation) 1
MTAP methylthioadenosine phosphorylase
MTRF1L mitochondrial translational release factor 1-like
MYRF myelin regulatory factor
NAAA N-acylethanolamine acid amidase
NCKIPSD NCK interacting protein with SH3 domain
NEBL nebulette
NF2 neurofibromin 2 (merlin)
NID1 nidogen 1
OGFR opioid growth factor receptor
OTUD4 OTU deubiquitinase 4
PAIP2B poly(A) binding protein interacting protein 2B
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDCD6 programmed cell death 6
PDE4DIP phosphodiesterase 4D interacting protein
PGAP1 post-GPI attachment to proteins 1
PHF7 PHD finger protein 7
PHTF2 putative homeodomain transcription factor 2
PKN1 protein kinase N1
PKNOX1 PBX/knotted 1 homeobox 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP5C protein phosphatase 5, catalytic subunit
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB3A RAB3A, member RAS oncogene family
RNF19B ring finger protein 19B
SAFB2 scaffold attachment factor B2
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SERGEF secretion regulating guanine nucleotide exchange factor
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A14 solute carrier family 22, member 14
SLC26A6 solute carrier family 26 (anion exchanger), member 6
STC1 stanniocalcin 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAOK3 TAO kinase 3
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THRAP3 thyroid hormone receptor associated protein 3
TJAP1 tight junction associated protein 1 (peripheral)
TLE4 transducin-like enhancer of split 4
TMCC1 transmembrane and coiled-coil domain family 1
TMEM212 transmembrane protein 212
TOP3B topoisomerase (DNA) III beta
VEGFA vascular endothelial growth factor A
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
WDR61 WD repeat domain 61
ZBTB22 zinc finger and BTB domain containing 22
ZC3H7B zinc finger CCCH-type containing 7B
ZNF274 zinc finger protein 274
ZNF358 zinc finger protein 358
ZNF500 zinc finger protein 500
ZNF747 zinc finger protein 747
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACP2 acid phosphatase 2, lysosomal
ANKEF1 ankyrin repeat and EF-hand domain containing 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APH1B APH1B gamma secretase subunit
ARHGAP11A Rho GTPase activating protein 11A
ASCC2 activating signal cointegrator 1 complex subunit 2
ASL argininosuccinate lyase
AXIN1 axin 1
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPQ centromere protein Q
CEP97 centrosomal protein 97kDa
CHML choroideremia-like (Rab escort protein 2)
CHST10 carbohydrate sulfotransferase 10
COMMD10 COMM domain containing 10
COQ10B coenzyme Q10 homolog B (S. cerevisiae)
CTAGE9 CTAGE family, member 9
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLL3 delta-like 3 (Drosophila)
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EML4 echinoderm microtubule associated protein like 4
EPHA4 EPH receptor A4
ERCC2 excision repair cross-complementation group 2
ERMP1 endoplasmic reticulum metallopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXL6 F-box and leucine-rich repeat protein 6
FCHO1 FCH domain only 1
FIP1L1 factor interacting with PAPOLA and CPSF1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FXN frataxin
GJC1 gap junction protein, gamma 1, 45kDa
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GRWD1 glutamate-rich WD repeat containing 1
HIST1H1E histone cluster 1, H1e
HIST1H2AG histone cluster 1, H2ag
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HPSE heparanase
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
HSPA4L heat shock 70kDa protein 4-like
HSPB8 heat shock 22kDa protein 8
JMJD4 jumonji domain containing 4
KIAA1462 KIAA1462
KIRREL kin of IRRE like (Drosophila)
KLC2 kinesin light chain 2
LIN37 lin-37 DREAM MuvB core complex component
LPAR6 lysophosphatidic acid receptor 6
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBD5 methyl-CpG binding domain protein 5
MCOLN1 mucolipin 1
MCRS1 microspherule protein 1
METTL21B methyltransferase like 21B
MTG1 mitochondrial ribosome-associated GTPase 1
NBEA neurobeachin
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
ORC1 origin recognition complex, subunit 1
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PALMD palmdelphin
PIBF1 progesterone immunomodulatory binding factor 1
PLSCR4 phospholipid scramblase 4
POMT1 protein-O-mannosyltransferase 1
RABL3 RAB, member of RAS oncogene family-like 3
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMHD1 SAM domain and HD domain 1
SH2B2 SH2B adaptor protein 2
SLC25A40 solute carrier family 25, member 40
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SUGP1 SURP and G patch domain containing 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYTL2 synaptotagmin-like 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TNS2 tensin 2
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN12 tetraspanin 12
TTBK2 tau tubulin kinase 2
TTC33 tetratricopeptide repeat domain 33
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF212 zinc finger protein 212
ZNF329 zinc finger protein 329
ZNF33B zinc finger protein 33B
ZNF770 zinc finger protein 770
ZNF813 zinc finger protein 813