arteriole Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A small branch of an artery (a vessel that carries blood high in oxygen away from the heart to the body) leading to a capillary. The oxygenated hemoglobin (oxyhemoglobin) makes the blood in arteries and arterioles look bright red. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001997)
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Genes

380 proteins co-occuring with the tissue arteriole in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
REN renin 2.72191
ACE angiotensin I converting enzyme 2.30412
NOS3 nitric oxide synthase 3 (endothelial cell) 2.28049
KNG1 kininogen 1 2.09631
ALB albumin 1.78235
EDN1 endothelin 1 1.75124
EDNRA endothelin receptor type A 1.67057
SOD2 superoxide dismutase 2, mitochondrial 1.66307
VWF von Willebrand factor 1.64056
GJA5 gap junction protein, alpha 5, 40kDa 1.61958
ADO 2-aminoethanethiol (cysteamine) dioxygenase 1.60912
CALCA calcitonin-related polypeptide alpha 1.60365
TAC1 tachykinin, precursor 1 1.57209
VEGFA vascular endothelial growth factor A 1.48411
NPPA natriuretic peptide A 1.47195
NOTCH3 notch 3 1.47148
NPY neuropeptide Y 1.46542
NOTCH4 notch 4 1.4246
GJA4 gap junction protein, alpha 4, 37kDa 1.38551
GUCY2C guanylate cyclase 2C 1.38002
NPR1 natriuretic peptide receptor 1 1.37773
CAT catalase 1.3759
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 1.36177
ANGPT1 angiopoietin 1 1.33953
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 1.30883
INS insulin 1.29984
AVP arginine vasopressin 1.27023
VIP vasoactive intestinal peptide 1.23807
CSN3 casein kappa 1.2296
CABIN1 calcineurin binding protein 1 1.21179
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 1.18157
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.18024
HBA1 hemoglobin, alpha 1 1.16072
HBA2 hemoglobin, alpha 2 1.15584
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 1.15362
FGF2 fibroblast growth factor 2 (basic) 1.15229
ICAM1 intercellular adhesion molecule 1 1.14963
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.11464
GJA1 gap junction protein, alpha 1, 43kDa 1.09916
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.08236
FGD1 FYVE, RhoGEF and PH domain containing 1 1.07397
TGFB1 transforming growth factor, beta 1 1.05985
GJC1 gap junction protein, gamma 1, 45kDa 1.0484
FN1 fibronectin 1 1.02513
ALPPL2 alkaline phosphatase, placental-like 2 1.01287
ALPL alkaline phosphatase, liver/bone/kidney 1.01243
F8 coagulation factor VIII, procoagulant component 1.01156
ALPP alkaline phosphatase, placental 1.01156
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.00414
F3 coagulation factor III (thromboplastin, tissue factor) 0.998473
FLT1 fms-related tyrosine kinase 1 0.997166
TH tyrosine hydroxylase 0.9889
ANXA7 annexin A7 0.984122
RICTOR RPTOR independent companion of MTOR, complex 2 0.981518
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.97935
CAV1 caveolin 1, caveolae protein, 22kDa 0.97935
ADM adrenomedullin 0.978482
NPS neuropeptide S 0.963767
CD34 CD34 molecule 0.950823
VCAM1 vascular cell adhesion molecule 1 0.937059
MME membrane metallo-endopeptidase 0.931051
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.908814
MMP2 matrix metallopeptidase 2 0.904978
NT5E 5'-nucleotidase, ecto (CD73) 0.893496
CST3 cystatin C 0.890525
TREX1 three prime repair exonuclease 1 0.889253
HMOX1 heme oxygenase 1 0.888829
PGF placental growth factor 0.876129
APOE apolipoprotein E 0.875284
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.86642
AGTR1 angiotensin II receptor, type 1 0.862206
DNAH8 dynein, axonemal, heavy chain 8 0.857995
TNF tumor necrosis factor 0.857574
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1 0.857153
ADORA1 adenosine A1 receptor 0.857153
PLAT plasminogen activator, tissue 0.854629
EPHX2 epoxide hydrolase 2, cytoplasmic 0.846225
MPV17 MpV17 mitochondrial inner membrane protein 0.845385
MMP9 matrix metallopeptidase 9 0.832385
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.826942
ESAM endothelial cell adhesion molecule 0.824849
SELE selectin E 0.81983
TBXAS1 thromboxane A synthase 1 (platelet) 0.816068
MYH11 myosin, heavy chain 11, smooth muscle 0.815233
EFNB2 ephrin-B2 0.809386
GP6 glycoprotein VI (platelet) 0.808968
WT1 Wilms tumor 1 0.801459
NOS1 nitric oxide synthase 1 (neuronal) 0.798541
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.789796
PDE5A phosphodiesterase 5A, cGMP-specific 0.788131
CTSC cathepsin C 0.78522
COL4A1 collagen, type IV, alpha 1 0.77857
FTL ferritin, light polypeptide 0.768612
TBXA2R thromboxane A2 receptor 0.768197
FTH1 ferritin, heavy polypeptide 1 0.760742
AQP1 aquaporin 1 (Colton blood group) 0.760328
MLX MLX, MAX dimerization protein 0.752057
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.752057
MPO myeloperoxidase 0.739678
PLG plasminogen 0.73803
FBXL20 F-box and leucine-rich repeat protein 20 0.735147
SELL selectin L 0.734323
MIS18A MIS18 kinetochore protein A 0.733089
FAM151B family with sequence similarity 151, member B 0.733089
EDN3 endothelin 3 0.733089
PCNA proliferating cell nuclear antigen 0.727741
CMA1 chymase 1, mast cell 0.721988
ADCY2 adenylate cyclase 2 (brain) 0.721988
SLC25A44 solute carrier family 25, member 44 0.717882
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.716651
VIPR1 vasoactive intestinal peptide receptor 1 0.711729
RYR1 ryanodine receptor 1 (skeletal) 0.7105
DUOX2 dual oxidase 2 0.701899
KLK1 kallikrein 1 0.700262
DUOX1 dual oxidase 1 0.699853
CLEC1B C-type lectin domain family 1, member B 0.698625
CRP C-reactive protein, pentraxin-related 0.698216
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 0.696172
GOLGA7 golgin A7 0.690042
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.681471
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.672506
PTGIS prostaglandin I2 (prostacyclin) synthase 0.665182
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.658678
UTS2 urotensin 2 0.658272
CCL2 chemokine (C-C motif) ligand 2 0.657866
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 0.656242
KIAA0101 KIAA0101 0.650966
PTH parathyroid hormone 0.650154
ENG endoglin 0.642454
ACHE acetylcholinesterase (Yt blood group) 0.634358
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.631123
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.630718
CD68 CD68 molecule 0.629101
ITM2B integral membrane protein 2B 0.628293
NOS2 nitric oxide synthase 2, inducible 0.626677
BRD4 bromodomain containing 4 0.622639
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.621428
PDLIM5 PDZ and LIM domain 5 0.621024
CD79A CD79a molecule, immunoglobulin-associated alpha 0.61699
MGAM maltase-glucoamylase 0.602892
HMOX2 heme oxygenase 2 0.599675
THBD thrombomodulin 0.598871
EPHB4 EPH receptor B4 0.598871
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.590839
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.586026
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.585224
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.584422
KDR kinase insert domain receptor 0.581218
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.579216
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.578816
PPARG peroxisome proliferator-activated receptor gamma 0.574416
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.568823
C5ORF38 chromosome 5 open reading frame 38 0.564833
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.564035
PRB3 proline-rich protein BstNI subfamily 3 0.563238
SST somatostatin 0.559652
ACTL7B actin-like 7B 0.558457
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.557661
VTA1 vesicle (multivesicular body) trafficking 1 0.555274
TRPC6 transient receptor potential cation channel, subfamily C, member 6 0.552093
CTGF connective tissue growth factor 0.549709
CDH5 cadherin 5, type 2 (vascular endothelium) 0.547326
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.540188
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.536625
SMTN smoothelin 0.534251
ANGPT2 angiopoietin 2 0.528719
ADA adenosine deaminase 0.524771
PXMP4 peroxisomal membrane protein 4, 24kDa 0.523588
LPA lipoprotein, Lp(a) 0.5228
IL1B interleukin 1, beta 0.520041
APLNR apelin receptor 0.513743
GPR75 G protein-coupled receptor 75 0.509813
TIMP1 TIMP metallopeptidase inhibitor 1 0.508242
SEBOX SEBOX homeobox 0.507457
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.502357
NPPC natriuretic peptide C 0.501965
TSPO translocator protein (18kDa) 0.501574
CBS cystathionine-beta-synthase 0.49844
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.494918
SOD3 superoxide dismutase 3, extracellular 0.494528
SELPLG selectin P ligand 0.492963
CASR calcium-sensing receptor 0.487496
FGF1 fibroblast growth factor 1 (acidic) 0.486326
PRTN3 proteinase 3 0.483206
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.482038
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.481648
ECE1 endothelin converting enzyme 1 0.479312
EDNRB endothelin receptor type B 0.478923
GZMM granzyme M (lymphocyte met-ase 1) 0.478145
MB myoglobin 0.477367
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.476979
GAL galanin/GMAP prepropeptide 0.47348
CALD1 caldesmon 1 0.470763
GCG glucagon 0.469599
DPP4 dipeptidyl-peptidase 4 0.46766
ACOT7 acyl-CoA thioesterase 7 0.466498
ACTL7A actin-like 7A 0.461078
PDYN prodynorphin 0.459145
GLB1 galactosidase, beta 1 0.453355
APLN apelin 0.450657
IGF1 insulin-like growth factor 1 (somatomedin C) 0.445653
F2 coagulation factor II (thrombin) 0.441426
NOTCH1 notch 1 0.439123
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.437589
VEGFB vascular endothelial growth factor B 0.42993
TPGS2 tubulin polyglutamylase complex subunit 2 0.429547
TIMP2 TIMP metallopeptidase inhibitor 2 0.429165
PGC progastricsin (pepsinogen C) 0.428783
ACE2 angiotensin I converting enzyme 2 0.428018
ADORA2A adenosine A2a receptor 0.428018
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.424199
EDA ectodysplasin A 0.417718
DLL4 delta-like 4 (Drosophila) 0.416195
P4HB prolyl 4-hydroxylase, beta polypeptide 0.414673
IGLV6-57 immunoglobulin lambda variable 6-57 0.413912
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.412771
RBMS2 RNA binding motif, single stranded interacting protein 2 0.412391
RBM20 RNA binding motif protein 20 0.408592
DDAH2 dimethylarginine dimethylaminohydrolase 2 0.408212
RGS5 regulator of G-protein signaling 5 0.407453
SPP1 secreted phosphoprotein 1 0.405555
ISCA2 iron-sulfur cluster assembly 2 0.401007
F5 coagulation factor V (proaccelerin, labile factor) 0.401007
IL6 interleukin 6 0.396844
TALDO1 transaldolase 1 0.396844
IGHA2 immunoglobulin heavy constant alpha 2 (A2m marker) 0.396465
KCNIP3 Kv channel interacting protein 3, calsenilin 0.395709
TAC3 tachykinin 3 0.393819
VEGFC vascular endothelial growth factor C 0.391931
EHF ets homologous factor 0.389666
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.38665
EXT1 exostosin glycosyltransferase 1 0.385896
NOX4 NADPH oxidase 4 0.38552
EDN2 endothelin 2 0.38439
SIX2 SIX homeobox 2 0.384013
MMP1 matrix metallopeptidase 1 0.383637
IGLV2-14 immunoglobulin lambda variable 2-14 0.382508
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.382508
GAN gigaxonin 0.380627
GRP gastrin-releasing peptide 0.378748
MTO1 mitochondrial tRNA translation optimization 1 0.376494
TACR1 tachykinin receptor 1 0.376119
BCHE butyrylcholinesterase 0.376119
MED17 mediator complex subunit 17 0.375368
MAPK3 mitogen-activated protein kinase 3 0.374993
CD151 CD151 molecule (Raph blood group) 0.373493
MMP3 matrix metallopeptidase 3 0.366007
F13B coagulation factor XIII, B polypeptide 0.364886
PDHX pyruvate dehydrogenase complex, component X 0.364886
PROKR1 prokineticin receptor 1 0.364886
TTR transthyretin 0.360409
TRIM25 tripartite motif containing 25 0.359292
ADM2 adrenomedullin 2 0.358174
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.357058
CXCL12 chemokine (C-X-C motif) ligand 12 0.35557
GPX1 glutathione peroxidase 1 0.353712
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.350743
PDGFB platelet-derived growth factor beta polypeptide 0.348519
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.348519
SNX10 sorting nexin 10 0.344079
THBS1 thrombospondin 1 0.341863
ADRA2C adrenoceptor alpha 2C 0.341495
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.340019
MYLK myosin light chain kinase 0.334865
CTC1 CTS telomere maintenance complex component 1 0.331194
CLIP3 CAP-GLY domain containing linker protein 3 0.330094
SPAG7 sperm associated antigen 7 0.329727
ADORA3 adenosine A3 receptor 0.32753
PNMA2 paraneoplastic Ma antigen 2 0.326798
LPAR1 lysophosphatidic acid receptor 1 0.326798
CHAT choline O-acetyltransferase 0.326067
ADRA1D adrenoceptor alpha 1D 0.323874
CD300LG CD300 molecule-like family member g 0.32205
ICAM2 intercellular adhesion molecule 2 0.32132
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.320956
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.318042
CCR2 chemokine (C-C motif) receptor 2 0.317679
HLA-DOB major histocompatibility complex, class II, DO beta 0.317315
MGP matrix Gla protein 0.314409
IGLV3-19 immunoglobulin lambda variable 3-19 0.312232
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.306444
TGFB3 transforming growth factor, beta 3 0.304279
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.303919
LBX2 ladybird homeobox 2 0.302478
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.302118
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.301039
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11 0.299242
IAPP islet amyloid polypeptide 0.298883
PLA2G1B phospholipase A2, group IB (pancreas) 0.298524
APOL1 apolipoprotein L, 1 0.294581
ADRB2 adrenoceptor beta 2, surface 0.294223
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.293866
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.293508
PRKG1 protein kinase, cGMP-dependent, type I 0.291722
EMILIN1 elastin microfibril interfacer 1 0.290652
CADM2 cell adhesion molecule 2 0.288158
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 0.287447
NES nestin 0.286381
RPL30 ribosomal protein L30 0.285671
TXN thioredoxin 0.284962
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.284607
CDH18 cadherin 18, type 2 0.283545
G6PD glucose-6-phosphate dehydrogenase 0.282837
SUCNR1 succinate receptor 1 0.28107
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.279659
BMPR1A bone morphogenetic protein receptor, type IA 0.276495
MMP7 matrix metallopeptidase 7 0.276495
BIRC5 baculoviral IAP repeat containing 5 0.276495
TPR translocated promoter region, nuclear basket protein 0.276145
MCAM melanoma cell adhesion molecule 0.274394
POMC proopiomelanocortin 0.274045
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.274045
SLC9A9 solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9 0.273346
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.272649
CLDN5 claudin 5 0.270909
CALCB calcitonin-related polypeptide beta 0.270214
LYZ lysozyme 0.268482
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.268137
HSPA12B heat shock 70kD protein 12B 0.268137
TNNT2 troponin T type 2 (cardiac) 0.267102
RPIA ribose 5-phosphate isomerase A 0.267102
PCBP4 poly(rC) binding protein 4 0.265725
F2R coagulation factor II (thrombin) receptor 0.265381
PROM1 prominin 1 0.262986
ADRB1 adrenoceptor beta 1 0.262304
RAP1A RAP1A, member of RAS oncogene family 0.261624
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1 0.259591
ACTG1 actin gamma 1 0.259254
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 0.258917
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.258243
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.257237
CD4 CD4 molecule 0.257237
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3 0.255567
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.254902
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.254239
NOSIP nitric oxide synthase interacting protein 0.253578
LDLR low density lipoprotein receptor 0.252919
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.251934
KRIT1 KRIT1, ankyrin repeat containing 0.250301
LALBA lactalbumin, alpha- 0.247399
TF transferrin 0.246442
PDE9A phosphodiesterase 9A 0.245807
NGFR nerve growth factor receptor 0.244545
PF4 platelet factor 4 0.243605
XAF1 XIAP associated factor 1 0.242363
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.241438
STXBP5 syntaxin binding protein 5 (tomosyn) 0.23961
FXYD4 FXYD domain containing ion transport regulator 4 0.239307
ALLC allantoicase 0.238706
ADORA2B adenosine A2b receptor 0.238706
FXYD7 FXYD domain containing ion transport regulator 7 0.236332
PTPRO protein tyrosine phosphatase, receptor type, O 0.23604
RBMS1 RNA binding motif, single stranded interacting protein 1 0.234016
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 0.232317
RNF34 ring finger protein 34, E3 ubiquitin protein ligase 0.23176
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.230931
TSPAN10 tetraspanin 10 0.230656
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.230656
CAV3 caveolin 3 0.229568
SLFN12 schlafen family member 12 0.228497
C5AR1 complement component 5a receptor 1 0.228234
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.22797
ACTB actin, beta 0.227186
RIN3 Ras and Rab interactor 3 0.223662
FLT4 fms-related tyrosine kinase 4 0.22246
ADRA2A adrenoceptor alpha 2A 0.222224
CR2 complement component (3d/Epstein Barr virus) receptor 2 0.220152
FXYD1 FXYD domain containing ion transport regulator 1 0.219928
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.219485
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.218613
ILK integrin-linked kinase 0.217974
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 0.217974
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.217762
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.217762
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.216933
DNM1 dynamin 1 0.21673
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.214954
AGXT2 alanine--glyoxylate aminotransferase 2 0.212936
TERF2 telomeric repeat binding factor 2 0.212413
SCX scleraxis basic helix-loop-helix transcription factor 0.212413