articaine-7272 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the articaine-7272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ANAPC5 anaphase promoting complex subunit 5
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APC adenomatous polyposis coli
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN3 ataxin 3
BIN1 bridging integrator 1
C10ORF88 chromosome 10 open reading frame 88
C7ORF69 chromosome 7 open reading frame 69
C9ORF156 chromosome 9 open reading frame 156
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CIDEB cell death-inducing DFFA-like effector b
CNPY4 canopy FGF signaling regulator 4
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL13A1 collagen, type XIII, alpha 1
COL3A1 collagen, type III, alpha 1
COPS8 COP9 signalosome subunit 8
CXCL3 chemokine (C-X-C motif) ligand 3
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
F3 coagulation factor III (thromboplastin, tissue factor)
FAM163A family with sequence similarity 163, member A
FBN2 fibrillin 2
FKBP8 FK506 binding protein 8, 38kDa
FZD1 frizzled class receptor 1
GADD45B growth arrest and DNA-damage-inducible, beta
GAS8 growth arrest-specific 8
GK glycerol kinase
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPATCH2L G patch domain containing 2-like
H2AFX H2A histone family, member X
HNF1B HNF1 homeobox B
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
IRF1 interferon regulatory factor 1
KCTD20 potassium channel tetramerization domain containing 20
KDM4B lysine (K)-specific demethylase 4B
KIAA1644 KIAA1644
LMNA lamin A/C
LMNB1 lamin B1
LOC644450 uncharacterized LOC644450
LRP6 low density lipoprotein receptor-related protein 6
LRRC41 leucine rich repeat containing 41
MBTD1 mbt domain containing 1
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MMP13 matrix metallopeptidase 13
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3
PDE4D phosphodiesterase 4D, cAMP-specific
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKNOX1 PBX/knotted 1 homeobox 1
PLIN2 perilipin 2
PRR7 proline rich 7 (synaptic)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB33B RAB33B, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF19B ring finger protein 19B
RPAIN RPA interacting protein
RUNX1 runt-related transcription factor 1
RUNX1-IT1 RUNX1 intronic transcript 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERTAD3 SERTA domain containing 3
SETD8 SET domain containing (lysine methyltransferase) 8
SGSM3 small G protein signaling modulator 3
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOCS6 suppressor of cytokine signaling 6
SOD3 superoxide dismutase 3, extracellular
SOX13 SRY (sex determining region Y)-box 13
SSBP2 single-stranded DNA binding protein 2
STBD1 starch binding domain 1
SYT17 synaptotagmin XVII
TBL3 transducin (beta)-like 3
TMCC1 transmembrane and coiled-coil domain family 1
TMCO6 transmembrane and coiled-coil domains 6
TNC tenascin C
TTC33 tetratricopeptide repeat domain 33
UNC45A unc-45 homolog A (C. elegans)
VARS valyl-tRNA synthetase
ZFYVE9 zinc finger, FYVE domain containing 9
ZHX2 zinc fingers and homeoboxes 2
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF675 zinc finger protein 675
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACADSB acyl-CoA dehydrogenase, short/branched chain
AFAP1 actin filament associated protein 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC6 armadillo repeat containing 6
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
AUH AU RNA binding protein/enoyl-CoA hydratase
AXIN1 axin 1
BIRC3 baculoviral IAP repeat containing 3
C11ORF80 chromosome 11 open reading frame 80
C4ORF19 chromosome 4 open reading frame 19
C7ORF43 chromosome 7 open reading frame 43
CARD8 caspase recruitment domain family, member 8
CASP8AP2 caspase 8 associated protein 2
CCNO cyclin O
CEMIP cell migration inducing protein, hyaluronan binding
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLDN15 claudin 15
CNGB3 cyclic nucleotide gated channel beta 3
CNTNAP1 contactin associated protein 1
COLGALT2 collagen beta(1-O)galactosyltransferase 2
DET1 de-etiolated homolog 1 (Arabidopsis)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
EDC4 enhancer of mRNA decapping 4
EFNA1 ephrin-A1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
F8 coagulation factor VIII, procoagulant component
FAF1 Fas (TNFRSF6) associated factor 1
FGGY FGGY carbohydrate kinase domain containing
FOXC1 forkhead box C1
FUZ fuzzy planar cell polarity protein
HDAC4 histone deacetylase 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HHLA3 HERV-H LTR-associating 3
HLX H2.0-like homeobox
HMGB3P1 high mobility group box 3 pseudogene 1
HOXA4 homeobox A4
HOXC8 homeobox C8
HYAL3 hyaluronoglucosaminidase 3
KATNBL1 katanin p80 subunit B-like 1
KIAA0513 KIAA0513
KIAA0922 KIAA0922
KIAA1462 KIAA1462
KISS1 KiSS-1 metastasis-suppressor
KPTN kaptin (actin binding protein)
LRP5L low density lipoprotein receptor-related protein 5-like
LZTR1 leucine-zipper-like transcription regulator 1
MCM9 minichromosome maintenance complex component 9
METTL22 methyltransferase like 22
MFSD11 major facilitator superfamily domain containing 11
MFSD12 major facilitator superfamily domain containing 12
MISP mitotic spindle positioning
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTG1 mitochondrial ribosome-associated GTPase 1
MTRF1 mitochondrial translational release factor 1
NBEAL2 neurobeachin-like 2
NKX3-2 NK3 homeobox 2
NLK nemo-like kinase
OCLN occludin
OLFML2A olfactomedin-like 2A
OPLAH 5-oxoprolinase (ATP-hydrolysing)
PCBP4 poly(rC) binding protein 4
PIEZO1 piezo-type mechanosensitive ion channel component 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKX protein kinase, X-linked
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTK6 protein tyrosine kinase 6
RAB17 RAB17, member RAS oncogene family
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RHOB ras homolog family member B
RIN1 Ras and Rab interactor 1
RNF38 ring finger protein 38
RPUSD2 RNA pseudouridylate synthase domain containing 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCARA3 scavenger receptor class A, member 3
SDF2 stromal cell-derived factor 2
SECTM1 secreted and transmembrane 1
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SUSD6 sushi domain containing 6
TESPA1 thymocyte expressed, positive selection associated 1
TIGD6 tigger transposable element derived 6
TMCC2 transmembrane and coiled-coil domain family 2
TMEM2 transmembrane protein 2
TOR4A torsin family 4, member A
TRABD TraB domain containing
TRIM66 tripartite motif containing 66
TRIP10 thyroid hormone receptor interactor 10
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
USP39 ubiquitin specific peptidase 39
VWA1 von Willebrand factor A domain containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZNF273 zinc finger protein 273
ZNF85 zinc finger protein 85
ZXDC ZXD family zinc finger C