| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the articaine-7272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ANAPC5 | anaphase promoting complex subunit 5 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| APC | adenomatous polyposis coli |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP5S | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B) |
| ATP7A | ATPase, Cu++ transporting, alpha polypeptide |
| ATXN3 | ataxin 3 |
| BIN1 | bridging integrator 1 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNPY4 | canopy FGF signaling regulator 4 |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COL13A1 | collagen, type XIII, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| COPS8 | COP9 signalosome subunit 8 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM163A | family with sequence similarity 163, member A |
| FBN2 | fibrillin 2 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FZD1 | frizzled class receptor 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAS8 | growth arrest-specific 8 |
| GK | glycerol kinase |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPATCH2L | G patch domain containing 2-like |
| H2AFX | H2A histone family, member X |
| HNF1B | HNF1 homeobox B |
| HOMER2 | homer scaffolding protein 2 |
| HOMER3 | homer scaffolding protein 3 |
| IRF1 | interferon regulatory factor 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KDM4B | lysine (K)-specific demethylase 4B |
| KIAA1644 | KIAA1644 |
| LMNA | lamin A/C |
| LMNB1 | lamin B1 |
| LOC644450 | uncharacterized LOC644450 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| LRRC41 | leucine rich repeat containing 41 |
| MBTD1 | mbt domain containing 1 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MMP13 | matrix metallopeptidase 13 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OGFOD3 | 2-oxoglutarate and iron-dependent oxygenase domain containing 3 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLIN2 | perilipin 2 |
| PRR7 | proline rich 7 (synaptic) |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| RAB33B | RAB33B, member RAS oncogene family |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RNF19B | ring finger protein 19B |
| RPAIN | RPA interacting protein |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERTAD3 | SERTA domain containing 3 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGSM3 | small G protein signaling modulator 3 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SMAD5 | SMAD family member 5 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOD3 | superoxide dismutase 3, extracellular |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SSBP2 | single-stranded DNA binding protein 2 |
| STBD1 | starch binding domain 1 |
| SYT17 | synaptotagmin XVII |
| TBL3 | transducin (beta)-like 3 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMCO6 | transmembrane and coiled-coil domains 6 |
| TNC | tenascin C |
| TTC33 | tetratricopeptide repeat domain 33 |
| UNC45A | unc-45 homolog A (C. elegans) |
| VARS | valyl-tRNA synthetase |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZHX2 | zinc fingers and homeoboxes 2 |
| ZNF286A | zinc finger protein 286A |
| ZNF34 | zinc finger protein 34 |
| ZNF675 | zinc finger protein 675 |
| ZRSR2 | zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| AFAP1 | actin filament associated protein 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARMC6 | armadillo repeat containing 6 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| AXIN1 | axin 1 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCNO | cyclin O |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHKB | choline kinase beta |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN15 | claudin 15 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNTNAP1 | contactin associated protein 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA1 | ephrin-A1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| F8 | coagulation factor VIII, procoagulant component |
| FAF1 | Fas (TNFRSF6) associated factor 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FOXC1 | forkhead box C1 |
| FUZ | fuzzy planar cell polarity protein |
| HDAC4 | histone deacetylase 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HHLA3 | HERV-H LTR-associating 3 |
| HLX | H2.0-like homeobox |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HOXA4 | homeobox A4 |
| HOXC8 | homeobox C8 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA0513 | KIAA0513 |
| KIAA0922 | KIAA0922 |
| KIAA1462 | KIAA1462 |
| KISS1 | KiSS-1 metastasis-suppressor |
| KPTN | kaptin (actin binding protein) |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MCM9 | minichromosome maintenance complex component 9 |
| METTL22 | methyltransferase like 22 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MISP | mitotic spindle positioning |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTRF1 | mitochondrial translational release factor 1 |
| NBEAL2 | neurobeachin-like 2 |
| NKX3-2 | NK3 homeobox 2 |
| NLK | nemo-like kinase |
| OCLN | occludin |
| OLFML2A | olfactomedin-like 2A |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PCBP4 | poly(rC) binding protein 4 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PRKX | protein kinase, X-linked |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTK6 | protein tyrosine kinase 6 |
| RAB17 | RAB17, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHOB | ras homolog family member B |
| RIN1 | Ras and Rab interactor 1 |
| RNF38 | ring finger protein 38 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SDF2 | stromal cell-derived factor 2 |
| SECTM1 | secreted and transmembrane 1 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SUSD6 | sushi domain containing 6 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM2 | transmembrane protein 2 |
| TOR4A | torsin family 4, member A |
| TRABD | TraB domain containing |
| TRIM66 | tripartite motif containing 66 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| USP39 | ubiquitin specific peptidase 39 |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF273 | zinc finger protein 273 |
| ZNF85 | zinc finger protein 85 |
| ZXDC | ZXD family zinc finger C |