articular Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The anguloarticular is a compound bone that results of the fusion of the dermal angular and the cartilaginous articular and forms the posterior part of the lower jaw. The dermal part ossifies initially on the posterolateral surface of Meckel's cartilage near the articulation with the quadrate (5.5 mm NL). A posterior process forms, creating a synovial joint with the quadrate. (Experimental Factor Ontology, EFO_0003530)
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Genes

135 genes co-occuring with the biological term articular in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACAN aggrecan
ADIPOQ adiponectin, C1Q and collagen domain containing
ANGPTL4 angiopoietin-like 4
ANKH ANKH inorganic pyrophosphate transport regulator
AQP1 aquaporin 1 (Colton blood group)
ASPN asporin
B3GAT3 beta-1,3-glucuronyltransferase 3
BGN biglycan
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BSG basigin (Ok blood group)
CD44 CD44 molecule (Indian blood group)
CILP2 cartilage intermediate layer protein 2
CLU clusterin
CMKLR1 chemerin chemokine-like receptor 1
COL10A1 collagen, type X, alpha 1
COL2A1 collagen, type II, alpha 1
COL6A3 collagen, type VI, alpha 3
COL6A4P1 collagen, type VI, alpha 4 pseudogene 1
COL9A1 collagen, type IX, alpha 1
COMP cartilage oligomeric matrix protein
CRP C-reactive protein, pentraxin-related
CRTAC1 cartilage acidic protein 1
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSK cathepsin K
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DCX doublecortin
DDR2 discoidin domain receptor tyrosine kinase 2
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DKK1 dickkopf WNT signaling pathway inhibitor 1
DPP4 dipeptidyl-peptidase 4
ELK1 ELK1, member of ETS oncogene family
EPAS1 endothelial PAS domain protein 1
ESRRA estrogen-related receptor alpha
FAP fibroblast activation protein, alpha
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF18 fibroblast growth factor 18
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FMOD fibromodulin
FN1 fibronectin 1
GDF5 growth differentiation factor 5
GREM1 gremlin 1, DAN family BMP antagonist
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAS1 hyaluronan synthase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB2 high mobility group box 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF1 insulin-like growth factor 1 (somatomedin C)
IL18 interleukin 18
IL1B interleukin 1, beta
IL21R interleukin 21 receptor
IL6 interleukin 6
IL6R interleukin 6 receptor
INHBA inhibin, beta A
ITGA10 integrin, alpha 10
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KDR kinase insert domain receptor
KERA keratocan
LEP leptin
LEPR leptin receptor
LIF leukemia inhibitory factor
LUM lumican
MAPK14 mitogen-activated protein kinase 14
MASP2 mannan-binding lectin serine peptidase 2
MATN3 matrilin 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDK midkine (neurite growth-promoting factor 2)
MIR223 microRNA 223
MIR675 microRNA 675
MIR9-1 microRNA 9-1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NAMPT nicotinamide phosphoribosyltransferase
NCR2 natural cytotoxicity triggering receptor 2
NLRP3 NLR family, pyrin domain containing 3
NR1D1 nuclear receptor subfamily 1, group D, member 1
NUCB2 nucleobindin 2
NUPR1 nuclear protein, transcriptional regulator, 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAUR plasminogen activator, urokinase receptor
POMC proopiomelanocortin
PRG4 proteoglycan 4
PRTG protogenin
PTGES prostaglandin E synthase
PTHLH parathyroid hormone-like hormone
RAP1A RAP1A, member of RAS oncogene family
RCOR1 REST corepressor 1
RETN resistin
S1PR1 sphingosine-1-phosphate receptor 1
SETDB1 SET domain, bifurcated 1
SFRP1 secreted frizzled-related protein 1
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SOX5 SRY (sex determining region Y)-box 5
SOX6 SRY (sex determining region Y)-box 6
SOX8 SRY (sex determining region Y)-box 8
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TIMP2 TIMP metallopeptidase inhibitor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
WISP1 WNT1 inducible signaling pathway protein 1
WISP3 WNT1 inducible signaling pathway protein 3
WNT3A wingless-type MMTV integration site family, member 3A
WNT7A wingless-type MMTV integration site family, member 7A