Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the ascorbic acid-5407 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
A1CF | APOBEC1 complementation factor |
ACVR1B | activin A receptor, type IB |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
ALDOB | aldolase B, fructose-bisphosphate |
ANXA2P3 | annexin A2 pseudogene 3 |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
C11ORF63 | chromosome 11 open reading frame 63 |
C14ORF79 | chromosome 14 open reading frame 79 |
C17ORF59 | chromosome 17 open reading frame 59 |
C1ORF105 | chromosome 1 open reading frame 105 |
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
CASP1 | caspase 1, apoptosis-related cysteine peptidase |
CLCN4 | chloride channel, voltage-sensitive 4 |
CLCN7 | chloride channel, voltage-sensitive 7 |
CLMN | calmin (calponin-like, transmembrane) |
CNOT4 | CCR4-NOT transcription complex, subunit 4 |
COMT | catechol-O-methyltransferase |
CORO2B | coronin, actin binding protein, 2B |
CRISP2 | cysteine-rich secretory protein 2 |
CSF1 | colony stimulating factor 1 (macrophage) |
CYHR1 | cysteine/histidine-rich 1 |
CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
DOCK6 | dedicator of cytokinesis 6 |
DPEP2 | dipeptidase 2 |
EFNB3 | ephrin-B3 |
FABP3 | fatty acid binding protein 3, muscle and heart |
FGL1 | fibrinogen-like 1 |
FMO5 | flavin containing monooxygenase 5 |
FSCN1 | fascin actin-bundling protein 1 |
GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
GJA4 | gap junction protein, alpha 4, 37kDa |
GPR15 | G protein-coupled receptor 15 |
GSPT2 | G1 to S phase transition 2 |
GSTP1 | glutathione S-transferase pi 1 |
HIST1H2BM | histone cluster 1, H2bm |
ICOSLG | inducible T-cell co-stimulator ligand |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IGF1R | insulin-like growth factor 1 receptor |
IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
KDM4C | lysine (K)-specific demethylase 4C |
KIAA1107 | KIAA1107 |
KMT2A | lysine (K)-specific methyltransferase 2A |
LAMA3 | laminin, alpha 3 |
LGALS8 | lectin, galactoside-binding, soluble, 8 |
LY6G6C | lymphocyte antigen 6 complex, locus G6C |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAGEA1 | melanoma antigen family A1 |
MAGEC1 | melanoma antigen family C1 |
MAOA | monoamine oxidase A |
MAP4 | microtubule-associated protein 4 |
MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
MBD3 | methyl-CpG binding domain protein 3 |
MYO1B | myosin IB |
NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
PCDHA3 | protocadherin alpha 3 |
PCDHB6 | protocadherin beta 6 |
PLAU | plasminogen activator, urokinase |
PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
PLCD1 | phospholipase C, delta 1 |
PON1 | paraoxonase 1 |
POU3F2 | POU class 3 homeobox 2 |
PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
PPP5C | protein phosphatase 5, catalytic subunit |
PTAFR | platelet-activating factor receptor |
PVT1 | Pvt1 oncogene (non-protein coding) |
RAD52 | RAD52 homolog (S. cerevisiae) |
RAG1 | recombination activating gene 1 |
RBBP9 | retinoblastoma binding protein 9 |
RBP4 | retinol binding protein 4, plasma |
RHEB | Ras homolog enriched in brain |
RIMS3 | regulating synaptic membrane exocytosis 3 |
S100A7 | S100 calcium binding protein A7 |
SFTPB | surfactant protein B |
SH3BP2 | SH3-domain binding protein 2 |
SIK3 | SIK family kinase 3 |
SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
SLC15A1 | solute carrier family 15 (oligopeptide transporter), member 1 |
SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
SLMO1 | slowmo homolog 1 (Drosophila) |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
STEAP4 | STEAP family member 4 |
TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
TBC1D2B | TBC1 domain family, member 2B |
TSNAXIP1 | translin-associated factor X interacting protein 1 |
VPS9D1 | VPS9 domain containing 1 |
VWA5A | von Willebrand factor A domain containing 5A |
WDR62 | WD repeat domain 62 |
ZEB1 | zinc finger E-box binding homeobox 1 |
ZFAND5 | zinc finger, AN1-type domain 5 |
Symbol | Name |
---|---|
ACSL4 | acyl-CoA synthetase long-chain family member 4 |
AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
ALPK1 | alpha-kinase 1 |
ANP32A-IT1 | ANP32A intronic transcript 1 |
ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
ARMC4 | armadillo repeat containing 4 |
BCAS1 | breast carcinoma amplified sequence 1 |
BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
BLNK | B-cell linker |
BRINP2 | bone morphogenetic protein/retinoic acid inducible neural-specific 2 |
BTBD2 | BTB (POZ) domain containing 2 |
BTF3P12 | basic transcription factor 3 pseudogene 12 |
C11ORF30 | chromosome 11 open reading frame 30 |
C16ORF45 | chromosome 16 open reading frame 45 |
C22ORF29 | chromosome 22 open reading frame 29 |
C4ORF29 | chromosome 4 open reading frame 29 |
CCDC85C | coiled-coil domain containing 85C |
CCDC88C | coiled-coil domain containing 88C |
CD8A | CD8a molecule |
CES3 | carboxylesterase 3 |
CLIC2 | chloride intracellular channel 2 |
CNGB3 | cyclic nucleotide gated channel beta 3 |
CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
DGAT1 | diacylglycerol O-acyltransferase 1 |
DSCAM | Down syndrome cell adhesion molecule |
DUSP13 | dual specificity phosphatase 13 |
DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
EGFL7 | EGF-like-domain, multiple 7 |
EPHX2 | epoxide hydrolase 2, cytoplasmic |
ERN2 | endoplasmic reticulum to nucleus signaling 2 |
F8 | coagulation factor VIII, procoagulant component |
FAM212B | family with sequence similarity 212, member B |
FILIP1L | filamin A interacting protein 1-like |
FOSL1 | FOS-like antigen 1 |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
HIST1H2AL | histone cluster 1, H2al |
HOXC5 | homeobox C5 |
HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
HSPA1L | heat shock 70kDa protein 1-like |
IFI27 | interferon, alpha-inducible protein 27 |
IGFBP6 | insulin-like growth factor binding protein 6 |
INO80D | INO80 complex subunit D |
IPO8 | importin 8 |
IRAK4 | interleukin-1 receptor-associated kinase 4 |
IRF6 | interferon regulatory factor 6 |
KDM5C | lysine (K)-specific demethylase 5C |
KLK5 | kallikrein-related peptidase 5 |
KPNA4 | karyopherin alpha 4 (importin alpha 3) |
LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
LIN7A | lin-7 homolog A (C. elegans) |
LOC390998 | ribosomal protein L10 pseudogene |
LOC730101 | uncharacterized LOC730101 |
LRP2 | low density lipoprotein receptor-related protein 2 |
MBNL3 | muscleblind-like splicing regulator 3 |
MTERF4 | mitochondrial transcription termination factor 4 |
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
NPM3 | nucleophosmin/nucleoplasmin 3 |
NT5DC3 | 5'-nucleotidase domain containing 3 |
OGFRL1 | opioid growth factor receptor-like 1 |
OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
PADI1 | peptidyl arginine deiminase, type I |
PAIP2B | poly(A) binding protein interacting protein 2B |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PDE12 | phosphodiesterase 12 |
PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
PGR | progesterone receptor |
PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
POM121 | POM121 transmembrane nucleoporin |
PTDSS2 | phosphatidylserine synthase 2 |
RNF126P1 | ring finger protein 126 pseudogene 1 |
SAYSD1 | SAYSVFN motif domain containing 1 |
SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
SLIT2 | slit homolog 2 (Drosophila) |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
STARD13 | StAR-related lipid transfer (START) domain containing 13 |
TBC1D19 | TBC1 domain family, member 19 |
TMEM254 | transmembrane protein 254 |
TOM1 | target of myb1 (chicken) |
TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
TTLL1 | tubulin tyrosine ligase-like family member 1 |
TUBA3C | tubulin, alpha 3c |
USP27X | ubiquitin specific peptidase 27, X-linked |
XAB2 | XPA binding protein 2 |
ZBTB48 | zinc finger and BTB domain containing 48 |
ZDHHC14 | zinc finger, DHHC-type containing 14 |
ZNF136 | zinc finger protein 136 |
ZNF250 | zinc finger protein 250 |
ZNF280D | zinc finger protein 280D |
ZNF282 | zinc finger protein 282 |
ZNF442 | zinc finger protein 442 |
ZNF574 | zinc finger protein 574 |
ZNF668 | zinc finger protein 668 |
ZNF669 | zinc finger protein 669 |