asiaticoside-2943 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the asiaticoside-2943 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSM3 acyl-CoA synthetase medium-chain family member 3
ACVR2A activin A receptor, type IIA
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADARB1 adenosine deaminase, RNA-specific, B1
ADGRA2 adhesion G protein-coupled receptor A2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARSB arylsulfatase B
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
C7ORF43 chromosome 7 open reading frame 43
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMSAP1 calmodulin regulated spectrin-associated protein 1
CCDC106 coiled-coil domain containing 106
CCSER2 coiled-coil serine-rich protein 2
CEP164 centrosomal protein 164kDa
CEP41 centrosomal protein 41kDa
CHD9 chromodomain helicase DNA binding protein 9
CLOCK clock circadian regulator
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPNE7 copine VII
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CUX1 cut-like homeobox 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FBXL18 F-box and leucine-rich repeat protein 18
FLRT2 fibronectin leucine rich transmembrane protein 2
FNTB farnesyltransferase, CAAX box, beta
GLE1 GLE1 RNA export mediator
GLRB glycine receptor, beta
GMPR guanosine monophosphate reductase
GPATCH4 G patch domain containing 4
GRSF1 G-rich RNA sequence binding factor 1
GSDMB gasdermin B
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HIST1H3G histone cluster 1, H3g
HIST1H4E histone cluster 1, H4e
HUS1 HUS1 checkpoint homolog (S. pombe)
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
KIAA0319L KIAA0319-like
KYNU kynureninase
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MIR22HG MIR22 host gene
MLANA melan-A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MMP25 matrix metallopeptidase 25
MTL5 metallothionein-like 5, testis-specific (tesmin)
NFRKB nuclear factor related to kappaB binding protein
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRCAM neuronal cell adhesion molecule
NTSR1 neurotensin receptor 1 (high affinity)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POLM polymerase (DNA directed), mu
PRAMEF11 PRAME family member 11
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PYGB phosphorylase, glycogen; brain
RAD51B RAD51 paralog B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOD ras homolog family member D
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SETD1A SET domain containing 1A
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC7 sialic acid binding Ig-like lectin 7
SIK3 SIK family kinase 3
SIKE1 suppressor of IKBKE 1
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3
SLC35F5 solute carrier family 35, member F5
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SMAD3 SMAD family member 3
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
STON1 stonin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX40 testis expressed 40
TNNT1 troponin T type 1 (skeletal, slow)
TRIM58 tripartite motif containing 58
TSC22D3 TSC22 domain family, member 3
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC13B unc-13 homolog B (C. elegans)
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP34 ubiquitin specific peptidase 34
USP53 ubiquitin specific peptidase 53
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF510 zinc finger protein 510

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACOX2 acyl-CoA oxidase 2, branched chain
ADAM23 ADAM metallopeptidase domain 23
APH1B APH1B gamma secretase subunit
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
C11ORF68 chromosome 11 open reading frame 68
C1ORF56 chromosome 1 open reading frame 56
C5 complement component 5
CCDC71 coiled-coil domain containing 71
CCL27 chemokine (C-C motif) ligand 27
CDK6 cyclin-dependent kinase 6
CES3 carboxylesterase 3
CHMP1A charged multivesicular body protein 1A
CIC capicua transcriptional repressor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL9A2 collagen, type IX, alpha 2
CRELD1 cysteine-rich with EGF-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DENND1C DENN/MADD domain containing 1C
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DUSP2 dual specificity phosphatase 2
DUSP8 dual specificity phosphatase 8
ECSIT ECSIT signalling integrator
EMILIN2 elastin microfibril interfacer 2
EXOSC1 exosome component 1
FBXL7 F-box and leucine-rich repeat protein 7
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FOXC1 forkhead box C1
GLCE glucuronic acid epimerase
GMIP GEM interacting protein
GPR85 G protein-coupled receptor 85
HIST1H1E histone cluster 1, H1e
HIST1H2BI histone cluster 1, H2bi
HIST1H2BO histone cluster 1, H2bo
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IFNA14 interferon, alpha 14
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRS1 insulin receptor substrate 1
ITGA10 integrin, alpha 10
KCNK5 potassium channel, two pore domain subfamily K, member 5
KDM5C lysine (K)-specific demethylase 5C
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIMD2 LIM domain containing 2
LINS lines homolog (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LZTR1 leucine-zipper-like transcription regulator 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP6D1 MAP6 domain containing 1
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL2B methyltransferase like 2B
MUM1 melanoma associated antigen (mutated) 1
MX1 MX dynamin-like GTPase 1
MXD3 MAX dimerization protein 3
NABP2 nucleic acid binding protein 2
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NPFFR1 neuropeptide FF receptor 1
NRGN neurogranin (protein kinase C substrate, RC3)
NT5M 5',3'-nucleotidase, mitochondrial
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXCT2 3-oxoacid CoA transferase 2
PDLIM1 PDZ and LIM domain 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PLA2G15 phospholipase A2, group XV
PLSCR4 phospholipid scramblase 4
PROCR protein C receptor, endothelial
PSKH1 protein serine kinase H1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP4 secretory carrier membrane protein 4
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SHPK sedoheptulokinase
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
STAT5A signal transducer and activator of transcription 5A
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAS2R10 taste receptor, type 2, member 10
TBXAS1 thromboxane A synthase 1 (platelet)
THRAP3 thyroid hormone receptor associated protein 3
TIMP2 TIMP metallopeptidase inhibitor 2
TPM3 tropomyosin 3
TRAF1 TNF receptor-associated factor 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
USB1 U6 snRNA biogenesis 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZC3H3 zinc finger CCCH-type containing 3
ZMAT5 zinc finger, matrin-type 5
ZNF329 zinc finger protein 329
ZNF862 zinc finger protein 862