asiaticoside-3504 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the asiaticoside-3504 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ACPP acid phosphatase, prostate
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
ADGRB1 adhesion G protein-coupled receptor B1
ALS2CL ALS2 C-terminal like
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP33 Rho GTPase activating protein 33
ATF6B activating transcription factor 6 beta
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BCL2A1 BCL2-related protein A1
BGN biglycan
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CDK19 cyclin-dependent kinase 19
CES3 carboxylesterase 3
CHN2 chimerin 2
COL6A1 collagen, type VI, alpha 1
COLEC10 collectin sub-family member 10 (C-type lectin)
CPQ carboxypeptidase Q
CXORF21 chromosome X open reading frame 21
CYLD cylindromatosis (turban tumor syndrome)
CYSLTR1 cysteinyl leukotriene receptor 1
DCHS2 dachsous cadherin-related 2
DDO D-aspartate oxidase
DEFB4A defensin, beta 4A
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLX2 distal-less homeobox 2
EGFL7 EGF-like-domain, multiple 7
ELOVL5 ELOVL fatty acid elongase 5
EML2 echinoderm microtubule associated protein like 2
FAM120C family with sequence similarity 120C
FAM155A family with sequence similarity 155, member A
FN1 fibronectin 1
FOXN3 forkhead box N3
GARNL3 GTPase activating Rap/RanGAP domain-like 3
GFI1 growth factor independent 1 transcription repressor
GLIPR1 GLI pathogenesis-related 1
GOSR2 golgi SNAP receptor complex member 2
GPC3 glypican 3
GPR4 G protein-coupled receptor 4
GUCY1A2 guanylate cyclase 1, soluble, alpha 2
GYPB glycophorin B (MNS blood group)
HIST1H3B histone cluster 1, H3b
HLA-C major histocompatibility complex, class I, C
HNF1A HNF1 homeobox A
HOXB9 homeobox B9
HP haptoglobin
ICOSLG inducible T-cell co-stimulator ligand
IFNA21 interferon, alpha 21
IGFBP5 insulin-like growth factor binding protein 5
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIAA0125 KIAA0125
KIAA0754 KIAA0754
KLHDC8A kelch domain containing 8A
KRT31 keratin 31, type I
KRT36 keratin 36, type I
LARP7 La ribonucleoprotein domain family, member 7
LRP12 low density lipoprotein receptor-related protein 12
MAPK10 mitogen-activated protein kinase 10
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NF2 neurofibromin 2 (merlin)
NOX1 NADPH oxidase 1
NPR1 natriuretic peptide receptor 1
NPY2R neuropeptide Y receptor Y2
OCA2 oculocutaneous albinism II
PKNOX2 PBX/knotted 1 homeobox 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLXNC1 plexin C1
PPARD peroxisome proliferator-activated receptor delta
PRB3 proline-rich protein BstNI subfamily 3
PTRF polymerase I and transcript release factor
RBM5 RNA binding motif protein 5
RND1 Rho family GTPase 1
RNF122 ring finger protein 122
RRAGD Ras-related GTP binding D
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
SC5D sterol-C5-desaturase
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SERHL2 serine hydrolase-like 2
SIPA1 signal-induced proliferation-associated 1
SLC12A8 solute carrier family 12, member 8
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
TCP10L t-complex 10-like
THRB thyroid hormone receptor, beta
TM4SF4 transmembrane 4 L six family member 4
TPMT thiopurine S-methyltransferase
UPK2 uroplakin 2
VGF VGF nerve growth factor inducible
WDR59 WD repeat domain 59
WDR62 WD repeat domain 62
ZCCHC24 zinc finger, CCHC domain containing 24
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATAD3A ATPase family, AAA domain containing 3A
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHCC1 BAH domain and coiled-coil containing 1
BBC3 BCL2 binding component 3
C10ORF95 chromosome 10 open reading frame 95
C14ORF132 chromosome 14 open reading frame 132
C16ORF62 chromosome 16 open reading frame 62
C19ORF40 chromosome 19 open reading frame 40
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCDC68 coiled-coil domain containing 68
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CENPO centromere protein O
CHKB choline kinase beta
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTAGE9 CTAGE family, member 9
DEAF1 DEAF1 transcription factor
DNMBP dynamin binding protein
DUSP8 dual specificity phosphatase 8
EFHD2 EF-hand domain family, member D2
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
EMID1 EMI domain containing 1
EPHA2 EPH receptor A2
ERCC4 excision repair cross-complementation group 4
FAM46C family with sequence similarity 46, member C
FBXO31 F-box protein 31
FLCN folliculin
FLRT3 fibronectin leucine rich transmembrane protein 3
FSTL3 follistatin-like 3 (secreted glycoprotein)
GID4 GID complex subunit 4
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPR87 G protein-coupled receptor 87
GRTP1 growth hormone regulated TBC protein 1
GTPBP2 GTP binding protein 2
HIST1H2BO histone cluster 1, H2bo
HOXC10 homeobox C10
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IDI2-AS1 IDI2 antisense RNA 1
INPP1 inositol polyphosphate-1-phosphatase
INPP5J inositol polyphosphate-5-phosphatase J
IRF1 interferon regulatory factor 1
JUNB jun B proto-oncogene
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM8 lysine (K)-specific demethylase 8
LARP6 La ribonucleoprotein domain family, member 6
LHX6 LIM homeobox 6
LIN37 lin-37 DREAM MuvB core complex component
LIN7B lin-7 homolog B (C. elegans)
LINC00339 long intergenic non-protein coding RNA 339
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MFAP2 microfibrillar-associated protein 2
MRPL52 mitochondrial ribosomal protein L52
N4BP3 NEDD4 binding protein 3
NBEAL2 neurobeachin-like 2
NECAB3 N-terminal EF-hand calcium binding protein 3
NT5C 5', 3'-nucleotidase, cytosolic
NT5DC3 5'-nucleotidase domain containing 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARD6A par-6 family cell polarity regulator alpha
PC pyruvate carboxylase
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PTK6 protein tyrosine kinase 6
PYCRL pyrroline-5-carboxylate reductase-like
RASA2 RAS p21 protein activator 2
RPGR retinitis pigmentosa GTPase regulator
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SMAD7 SMAD family member 7
SSBP3 single stranded DNA binding protein 3
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STK16 serine/threonine kinase 16
SYNGR3 synaptogyrin 3
TMC5 transmembrane channel-like 5
TMEM104 transmembrane protein 104
TMEM121 transmembrane protein 121
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
VAV1 vav 1 guanine nucleotide exchange factor
WLS wntless Wnt ligand secretion mediator
ZNF212 zinc finger protein 212
ZNF37BP zinc finger protein 37B, pseudogene