asiaticoside-7244 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the asiaticoside-7244 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ADCK2 aarF domain containing kinase 2
ANOS1 anosmin 1
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARNT aryl hydrocarbon receptor nuclear translocator
ASB13 ankyrin repeat and SOCS box containing 13
ATP9A ATPase, class II, type 9A
BAHCC1 BAH domain and coiled-coil containing 1
C10ORF88 chromosome 10 open reading frame 88
C1S complement component 1, s subcomponent
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC9 coiled-coil domain containing 9
CIDEB cell death-inducing DFFA-like effector b
CLDN14 claudin 14
COPS8 COP9 signalosome subunit 8
CREBZF CREB/ATF bZIP transcription factor
CTAGE5 CTAGE family, member 5
DAGLA diacylglycerol lipase, alpha
DIO3 deiodinase, iodothyronine, type III
DPF3 D4, zinc and double PHD fingers, family 3
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGFR epidermal growth factor receptor
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FA2H fatty acid 2-hydroxylase
FAM174B family with sequence similarity 174, member B
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FYB FYN binding protein
GDAP2 ganglioside induced differentiation associated protein 2
GOLGA1 golgin A1
GREB1L growth regulation by estrogen in breast cancer-like
GSR glutathione reductase
HPS4 Hermansky-Pudlak syndrome 4
IFI44L interferon-induced protein 44-like
IL1RN interleukin 1 receptor antagonist
ING1 inhibitor of growth family, member 1
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITM2B integral membrane protein 2B
KDM7A lysine (K)-specific demethylase 7A
L3MBTL1 l(3)mbt-like 1 (Drosophila)
MAP7 microtubule-associated protein 7
MARS methionyl-tRNA synthetase
MED16 mediator complex subunit 16
MED7 mediator complex subunit 7
MKL1 megakaryoblastic leukemia (translocation) 1
MOCS3 molybdenum cofactor synthesis 3
MPZL2 myelin protein zero-like 2
MSL3 male-specific lethal 3 homolog (Drosophila)
MTMR1 myotubularin related protein 1
MTUS1 microtubule associated tumor suppressor 1
NAAA N-acylethanolamine acid amidase
NMBR neuromedin B receptor
PHTF2 putative homeodomain transcription factor 2
PIDD1 p53-induced death domain protein 1
PKP3 plakophilin 3
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMCH pro-melanin-concentrating hormone
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PNPLA4 patatin-like phospholipase domain containing 4
PRR15L proline rich 15-like
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QKI QKI, KH domain containing, RNA binding
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RARG retinoic acid receptor, gamma
RBM19 RNA binding motif protein 19
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNFT1 ring finger protein, transmembrane 1
RPAIN RPA interacting protein
SDC2 syndecan 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SIRT6 sirtuin 6
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SREBF2 sterol regulatory element binding transcription factor 2
SS18 synovial sarcoma translocation, chromosome 18
SYNJ2 synaptojanin 2
SYNPO synaptopodin
SYT17 synaptotagmin XVII
TLE4 transducin-like enhancer of split 4
TMEM231 transmembrane protein 231
TMEM242 transmembrane protein 242
TUBGCP2 tubulin, gamma complex associated protein 2
USP19 ubiquitin specific peptidase 19
VAC14 Vac14 homolog (S. cerevisiae)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VASH1 vasohibin 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZER1 zyg-11 related, cell cycle regulator
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF277 zinc finger protein 277
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF467 zinc finger protein 467
ZNF75D zinc finger protein 75D
ZNF84 zinc finger protein 84

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANAPC2 anaphase promoting complex subunit 2
ANG angiogenin, ribonuclease, RNase A family, 5
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P3 annexin A2 pseudogene 3
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARF5 ADP-ribosylation factor 5
ASCC2 activating signal cointegrator 1 complex subunit 2
ATP13A2 ATPase type 13A2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L2 BCL2-like 2
BCORL1 BCL6 corepressor-like 1
CALCOCO1 calcium binding and coiled-coil domain 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCNE1 cyclin E1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLASRP CLK4-associating serine/arginine rich protein
CLEC16A C-type lectin domain family 16, member A
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CTAGE9 CTAGE family, member 9
CTNNBL1 catenin, beta like 1
CUL9 cullin 9
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUS2 dihydrouridine synthase 2
ECHDC1 ethylmalonyl-CoA decarboxylase 1
EVPL envoplakin
EXOSC5 exosome component 5
FAM193B family with sequence similarity 193, member B
FANCE Fanconi anemia, complementation group E
FEM1C fem-1 homolog c (C. elegans)
FGGY FGGY carbohydrate kinase domain containing
GATA6 GATA binding protein 6
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AE histone cluster 1, H2ae
HOXC8 homeobox C8
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2
IPO4 importin 4
KCTD15 potassium channel tetramerization domain containing 15
KRT4 keratin 4, type II
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAGEF1 melanoma antigen family F1
MANSC1 MANSC domain containing 1
MAP6D1 MAP6 domain containing 1
MEIS3P1 Meis homeobox 3 pseudogene 1
MFGE8 milk fat globule-EGF factor 8 protein
MFSD10 major facilitator superfamily domain containing 10
MTG1 mitochondrial ribosome-associated GTPase 1
MTRF1 mitochondrial translational release factor 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NT5C 5', 3'-nucleotidase, cytosolic
ORAI3 ORAI calcium release-activated calcium modulator 3
OSMR oncostatin M receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PALMD palmdelphin
PDZD2 PDZ domain containing 2
PELP1 proline, glutamate and leucine rich protein 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
POLI polymerase (DNA directed) iota
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
POMT1 protein-O-mannosyltransferase 1
RBL1 retinoblastoma-like 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REPS2 RALBP1 associated Eps domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
RPGR retinitis pigmentosa GTPase regulator
RPS17P5 ribosomal protein S17 pseudogene 5
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SAMD9 sterile alpha motif domain containing 9
SDC3 syndecan 3
SETMAR SET domain and mariner transposase fusion gene
SHPK sedoheptulokinase
SLC12A8 solute carrier family 12, member 8
SLC31A2 solute carrier family 31 (copper transporter), member 2
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
TCTN2 tectonic family member 2
TGFB3 transforming growth factor, beta 3
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS2 tensin 2
TOE1 target of EGR1, member 1 (nuclear)
TOR4A torsin family 4, member A
TPST2 tyrosylprotein sulfotransferase 2
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
WARS2 tryptophanyl tRNA synthetase 2, mitochondrial
ZNHIT2 zinc finger, HIT-type containing 2