aspartic-type peptidase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile. (Gene Ontology, GO_0070001)
External Link http://amigo.geneontology.org/amigo/term/GO:0070001
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Genes

25 genes performing the aspartic-type peptidase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ASPRV1 aspartic peptidase, retroviral-like 1
ASTL astacin-like metallo-endopeptidase (M12 family)
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
BACE1 beta-site APP-cleaving enzyme 1
BACE2 beta-site APP-cleaving enzyme 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CTSD cathepsin D
CTSE cathepsin E
DDI1 DNA-damage inducible 1 homolog 1 (S. cerevisiae)
DDI2 DNA-damage inducible 1 homolog 2 (S. cerevisiae)
HM13 histocompatibility (minor) 13
NAPSA napsin A aspartic peptidase
NRIP2 nuclear receptor interacting protein 2
NRIP3 nuclear receptor interacting protein 3
PGA4 pepsinogen 4, group I (pepsinogen A)
PGA5 pepsinogen 5, group I (pepsinogen A)
PGC progastricsin (pepsinogen C)
PIP prolactin-induced protein
PSEN1 presenilin 1
PSEN2 presenilin 2
REN renin
SPPL2A signal peptide peptidase like 2A
SPPL2B signal peptide peptidase like 2B
SPPL2C signal peptide peptidase like 2C
SPPL3 signal peptide peptidase like 3
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