aspiration pneumonitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A pneumonia that is defined as an acute lung injury after the inhalation of foreign material such as regurgitated acidic gastric contents, petroleum products and laxative oils. This syndrome occurs in patients who have a marked disturbance of consciousness such as that resulting from a drug overdose, seizures, a massive cerebrovascular accident, or the use of anesthesia. Aspiration of gastric contents results in a chemical burn of the tracheobronchial tree and pulmonary parenchyma, causing an intense parenchymal inflammatory reaction. The disesae has_symptom non-productive cough, has_symptom tachypnea, has_symptom bronchospasm, has_symptom bloody sputum, has_symptom frothy sputum, or has_symptom respiratory distress, 2-5 hrs after aspiration. (Human Disease Ontology, DOID_3240)
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Genes

29 genes co-occuring with the disease aspiration pneumonitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PPCS phosphopantothenoylcysteine synthetase 1.46232
HRH2 histamine receptor H2 1.23343
IFT80 intraflagellar transport 80 1.17636
CPVL carboxypeptidase, vitellogenic-like 0.897872
PNMA1 paraneoplastic Ma antigen 1 0.849945
LY75 lymphocyte antigen 75 0.812642
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.782707
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.782298
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.745172
IPP intracisternal A particle-promoted polypeptide 0.712392
ALB albumin 0.509959
HIST2H2AC histone cluster 2, H2ac 0.45447
HIST2H2AA4 histone cluster 2, H2aa4 0.454093
HIST2H2AA3 histone cluster 2, H2aa3 0.454093
MLN motilin 0.442042
CAT catalase 0.419892
PABPN1 poly(A) binding protein, nuclear 1 0.405305
GAST gastrin 0.326646
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.311377
FLNC filamin C, gamma 0.28151
SELL selectin L 0.264431
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.258417
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.231448
GUSB glucuronidase, beta 0.200331
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.179802
ICAM1 intercellular adhesion molecule 1 0.165217
MUC1 mucin 1, cell surface associated 0.148516
FLT1 fms-related tyrosine kinase 1 0.146176
TSPO translocator protein (18kDa) 0.145548