aspirin-induced asthma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A type of asthma in which aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) that inhibit cyclooxygen-ase 1 (COX-1) exacerbate bronchoconstriction. (Human Phenotype Ontology, HP_0012042)
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21 genes associated with the aspirin-induced asthma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
SBF1 SET binding factor 1 1.11203
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 1.08774
SGSM1 small G protein signaling modulator 1 1.01499
DCBLD2 discoidin, CUB and LCCL domain containing 2 1.00059
DCAF4 DDB1 and CUL4 associated factor 4 0.844241
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.833415
TSC1 tuberous sclerosis 1 0.772313
FILIP1 filamin A interacting protein 1 0.726078
CEP68 centrosomal protein 68kDa 0.726078
LRRC43 leucine rich repeat containing 43 0.690584
CIITA class II, major histocompatibility complex, transactivator 0.690584
PDZD2 PDZ domain containing 2 0.690584
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.661809
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 0.661809
AK8 adenylate kinase 8 0.636409
ZFYVE1 zinc finger, FYVE domain containing 1 0.622073
DCDC2 doublecortin domain containing 2 0.620125
C6 complement component 6 0.616892
ILVBL ilvB (bacterial acetolactate synthase)-like 0.600435
RBM25 RNA binding motif protein 25 0.561769
MEIS1 Meis homeobox 1 0.471696