| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the astemizole-1365 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHCYL1 | adenosylhomocysteinase-like 1 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| ANXA2 | annexin A2 |
| AQP9 | aquaporin 9 |
| ARL1 | ADP-ribosylation factor-like 1 |
| ATXN7 | ataxin 7 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL3 | B-cell CLL/lymphoma 3 |
| BMP2K | BMP2 inducible kinase |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C14ORF1 | chromosome 14 open reading frame 1 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNG2 | cyclin G2 |
| CCS | copper chaperone for superoxide dismutase |
| CD83 | CD83 molecule |
| CD86 | CD86 molecule |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CHKA | choline kinase alpha |
| CLEC7A | C-type lectin domain family 7, member A |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DERL2 | derlin 2 |
| DHCR7 | 7-dehydrocholesterol reductase |
| DSCR3 | Down syndrome critical region 3 |
| EGR2 | early growth response 2 |
| EIF1B | eukaryotic translation initiation factor 1B |
| ENO3 | enolase 3 (beta, muscle) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVI5 | ecotropic viral integration site 5 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPNMB | glycoprotein (transmembrane) nmb |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOMER1 | homer scaffolding protein 1 |
| IER3 | immediate early response 3 |
| IFI30 | interferon, gamma-inducible protein 30 |
| IL1R1 | interleukin 1 receptor, type I |
| INSIG1 | insulin induced gene 1 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KIAA1109 | KIAA1109 |
| KIZ | kizuna centrosomal protein |
| KLF11 | Kruppel-like factor 11 |
| LDLR | low density lipoprotein receptor |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LPIN1 | lipin 1 |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MSMO1 | methylsterol monooxygenase 1 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| NAAA | N-acylethanolamine acid amidase |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NRP2 | neuropilin 2 |
| OSBPL11 | oxysterol binding protein-like 11 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLSCR1 | phospholipid scramblase 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| RAB5C | RAB5C, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) |
| RGS1 | regulator of G-protein signaling 1 |
| RGS2 | regulator of G-protein signaling 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SDCBP | syndecan binding protein (syntenin) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| SPDEF | SAM pointed domain containing ETS transcription factor |
| SPP1 | secreted phosphoprotein 1 |
| SQSTM1 | sequestosome 1 |
| STK19 | serine/threonine kinase 19 |
| TMEM251 | transmembrane protein 251 |
| TMEM8A | transmembrane protein 8A |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TOX4 | TOX high mobility group box family member 4 |
| TRADD | TNFRSF1A-associated via death domain |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| Symbol | Name |
|---|---|
| ABT1 | activator of basal transcription 1 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 |
| ADRB2 | adrenoceptor beta 2, surface |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BCCIP | BRCA2 and CDKN1A interacting protein |
| C5ORF22 | chromosome 5 open reading frame 22 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CA2 | carbonic anhydrase II |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC15 | coiled-coil domain containing 15 |
| CCNT1 | cyclin T1 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CER1 | cerberus 1, DAN family BMP antagonist |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CNOT6 | CCR4-NOT transcription complex, subunit 6 |
| COPS7B | COP9 signalosome subunit 7B |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| DEAF1 | DEAF1 transcription factor |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| DOK2 | docking protein 2, 56kDa |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM46A | family with sequence similarity 46, member A |
| GATAD2A | GATA zinc finger domain containing 2A |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GTPBP3 | GTP binding protein 3 (mitochondrial) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1C | histone cluster 1, H1c |
| IL2RB | interleukin 2 receptor, beta |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0894 | KIAA0894 protein |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LBR | lamin B receptor |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMNB1 | lamin B1 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MMP9 | matrix metallopeptidase 9 |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL24 | mitochondrial ribosomal protein L24 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NCKAP1L | NCK-associated protein 1-like |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUCB2 | nucleobindin 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK1IP1 | PAK1 interacting protein 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PIGR | polymeric immunoglobulin receptor |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAC8 | placenta-specific 8 |
| PRR14L | proline rich 14-like |
| PRTN3 | proteinase 3 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RBBP5 | retinoblastoma binding protein 5 |
| RBM15B | RNA binding motif protein 15B |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| S100A9 | S100 calcium binding protein A9 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| STAC | SH3 and cysteine rich domain |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TBL3 | transducin (beta)-like 3 |
| TCTN2 | tectonic family member 2 |
| TDRD7 | tudor domain containing 7 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TSPAN32 | tetraspanin 32 |
| TUBA3C | tubulin, alpha 3c |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| URGCP | upregulator of cell proliferation |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF652 | zinc finger protein 652 |
| ZNF654 | zinc finger protein 654 |
| ZNF669 | zinc finger protein 669 |
