| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the astemizole-2049 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATF3 | activating transcription factor 3 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCPG1 | cell cycle progression 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLEC11A | C-type lectin domain family 11, member A |
| CLEC2B | C-type lectin domain family 2, member B |
| CORO2A | coronin, actin binding protein, 2A |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CTH | cystathionine gamma-lyase |
| CTNS | cystinosin, lysosomal cystine transporter |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYB5R2 | cytochrome b5 reductase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP5 | dual specificity phosphatase 5 |
| DYM | dymeclin |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FBN2 | fibrillin 2 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H4E | histone cluster 1, H4e |
| HOXC11 | homeobox C11 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IHH | indian hedgehog |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| ING4 | inhibitor of growth family, member 4 |
| INSIG1 | insulin induced gene 1 |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL36 | kelch-like family member 36 |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| LDLR | low density lipoprotein receptor |
| MED28 | mediator complex subunit 28 |
| MIIP | migration and invasion inhibitory protein |
| MINK1 | misshapen-like kinase 1 |
| MORN1 | MORN repeat containing 1 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYRF | myelin regulatory factor |
| NEK3 | NIMA-related kinase 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PF4 | platelet factor 4 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PMEL | premelanosome protein |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PTCH1 | patched 1 |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RRAGD | Ras-related GTP binding D |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SQSTM1 | sequestosome 1 |
| STC2 | stanniocalcin 2 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| THBS3 | thrombospondin 3 |
| TLN2 | talin 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM50B | transmembrane protein 50B |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| TTC9 | tetratricopeptide repeat domain 9 |
| UBQLN4 | ubiquilin 4 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| XDH | xanthine dehydrogenase |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF358 | zinc finger protein 358 |
| ZNF74 | zinc finger protein 74 |
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ABT1 | activator of basal transcription 1 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AXIN1 | axin 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BDNF | brain-derived neurotrophic factor |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C11ORF73 | chromosome 11 open reading frame 73 |
| C1ORF112 | chromosome 1 open reading frame 112 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CD70 | CD70 molecule |
| CDC7 | cell division cycle 7 |
| CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
| CRNKL1 | crooked neck pre-mRNA splicing factor 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DIXDC1 | DIX domain containing 1 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DOLK | dolichol kinase |
| DTWD1 | DTW domain containing 1 |
| EXOSC9 | exosome component 9 |
| FAM111A | family with sequence similarity 111, member A |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GLMN | glomulin, FKBP associated protein |
| GMIP | GEM interacting protein |
| GPATCH2 | G patch domain containing 2 |
| HIRA | histone cell cycle regulator |
| HJURP | Holliday junction recognition protein |
| HOMER1 | homer scaffolding protein 1 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HSPA2 | heat shock 70kDa protein 2 |
| IRS1 | insulin receptor substrate 1 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0556 | KIAA0556 |
| KIAA0586 | KIAA0586 |
| KIF13B | kinesin family member 13B |
| KIF20A | kinesin family member 20A |
| KIF20B | kinesin family member 20B |
| KIF23 | kinesin family member 23 |
| KIFC1 | kinesin family member C1 |
| KNOP1 | lysine-rich nucleolar protein 1 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAGEF1 | melanoma antigen family F1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBD5 | methyl-CpG binding domain protein 5 |
| MOB3B | MOB kinase activator 3B |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
| NARFL | nuclear prelamin A recognition factor-like |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) |
| NDC80 | NDC80 kinetochore complex component |
| NDRG4 | NDRG family member 4 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| NUPL2 | nucleoporin like 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PRAME | preferentially expressed antigen in melanoma |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SHROOM2 | shroom family member 2 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMAGP | small cell adhesion glycoprotein |
| SNX10 | sorting nexin 10 |
| SYNPO | synaptopodin |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| WDR46 | WD repeat domain 46 |
| XAB2 | XPA binding protein 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF107 | zinc finger protein 107 |
| ZNF175 | zinc finger protein 175 |
| ZNF177 | zinc finger protein 177 |
| ZNF189 | zinc finger protein 189 |
| ZNF239 | zinc finger protein 239 |
| ZNF394 | zinc finger protein 394 |
| ZNF85 | zinc finger protein 85 |
