| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the astemizole-2211 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARC | activity-regulated cytoskeleton-associated protein |
| ARL14 | ADP-ribosylation factor-like 14 |
| ATF3 | activating transcription factor 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCNG2 | cyclin G2 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DLX2 | distal-less homeobox 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EFNA1 | ephrin-A1 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EGR4 | early growth response 4 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM46C | family with sequence similarity 46, member C |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAP43 | growth associated protein 43 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HIST1H4E | histone cluster 1, H4e |
| HIST1H4H | histone cluster 1, H4h |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| IRS2 | insulin receptor substrate 2 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| JUN | jun proto-oncogene |
| KIAA0125 | KIAA0125 |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LDLR | low density lipoprotein receptor |
| LPIN1 | lipin 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MVD | mevalonate (diphospho) decarboxylase |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NF2 | neurofibromin 2 (merlin) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLM | polymerase (DNA directed), mu |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RCAN1 | regulator of calcineurin 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RND1 | Rho family GTPase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SRPK2 | SRSF protein kinase 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TRIM29 | tripartite motif containing 29 |
| TXNIP | thioredoxin interacting protein |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AR | androgen receptor |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCNE2 | cyclin E2 |
| CD34 | CD34 molecule |
| CDON | cell adhesion associated, oncogene regulated |
| CEL | carboxyl ester lipase |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DMTN | dematin actin binding protein |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| E2F8 | E2F transcription factor 8 |
| EMID1 | EMI domain containing 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GLI3 | GLI family zinc finger 3 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H3E | histone cluster 1, H3e |
| HOXA4 | homeobox A4 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL17RA | interleukin 17 receptor A |
| IL17RB | interleukin 17 receptor B |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KIAA0754 | KIAA0754 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAGEB2 | melanoma antigen family B2 |
| MAP6D1 | MAP6 domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYOZ1 | myozenin 1 |
| NEK11 | NIMA-related kinase 11 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| PADI1 | peptidyl arginine deiminase, type I |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAC1 | placenta-specific 1 |
| PLD3 | phospholipase D family, member 3 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| POM121 | POM121 transmembrane nucleoporin |
| PQLC2 | PQ loop repeat containing 2 |
| RAB3D | RAB3D, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SEC14L5 | SEC14-like 5 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC2A4RG | SLC2A4 regulator |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPRYD7 | SPRY domain containing 7 |
| STAG3 | stromal antigen 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SYNC | syncoilin, intermediate filament protein |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TESC | tescalcin |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM110 | transmembrane protein 110 |
| TMEM164 | transmembrane protein 164 |
| UNC119 | unc-119 homolog (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR76 | WD repeat domain 76 |
| ZIC3 | Zic family member 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF41 | zinc finger protein 41 |
