| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the astemizole-4471 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| C1ORF116 | chromosome 1 open reading frame 116 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EGR1 | early growth response 1 |
| FAM46A | family with sequence similarity 46, member A |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GGT1 | gamma-glutamyltransferase 1 |
| GK | glycerol kinase |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNB1 | interferon, beta 1, fibroblast |
| IL11 | interleukin 11 |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| INSIG1 | insulin induced gene 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUND | jun D proto-oncogene |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| KRT34 | keratin 34, type I |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PGK1 | phosphoglycerate kinase 1 |
| PHOX2B | paired-like homeobox 2b |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGES | prostaglandin E synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS4 | regulator of G-protein signaling 4 |
| RND1 | Rho family GTPase 1 |
| RNF39 | ring finger protein 39 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SEC24D | SEC24 family member D |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SQLE | squalene epoxidase |
| SQSTM1 | sequestosome 1 |
| TBX6 | T-box 6 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM29 | tripartite motif containing 29 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BAG4 | BCL2-associated athanogene 4 |
| BBS7 | Bardet-Biedl syndrome 7 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CEP295 | centrosomal protein 295kDa |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COBL | cordon-bleu WH2 repeat protein |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPNE7 | copine VII |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTSO | cathepsin O |
| DCLRE1A | DNA cross-link repair 1A |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ECM1 | extracellular matrix protein 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| F2R | coagulation factor II (thrombin) receptor |
| FAM50B | family with sequence similarity 50, member B |
| FHOD1 | formin homology 2 domain containing 1 |
| FZD3 | frizzled class receptor 3 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPATCH1 | G patch domain containing 1 |
| GRAMD1C | GRAM domain containing 1C |
| GRPR | gastrin-releasing peptide receptor |
| HOXA2 | homeobox A2 |
| HOXA4 | homeobox A4 |
| IFT81 | intraflagellar transport 81 |
| IL1B | interleukin 1, beta |
| INCENP | inner centromere protein antigens 135/155kDa |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| IRS1 | insulin receptor substrate 1 |
| KIAA1549L | KIAA1549-like |
| KIF3A | kinesin family member 3A |
| KLHDC4 | kelch domain containing 4 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMNB1 | lamin B1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MANBA | mannosidase, beta A, lysosomal |
| MCM3 | minichromosome maintenance complex component 3 |
| MOXD1 | monooxygenase, DBH-like 1 |
| NDP | Norrie disease (pseudoglioma) |
| NME5 | NME/NM23 family member 5 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PER3 | period circadian clock 3 |
| POLH | polymerase (DNA directed), eta |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B |
| PRR14L | proline rich 14-like |
| PRR4 | proline rich 4 (lacrimal) |
| QSER1 | glutamine and serine rich 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SDC3 | syndecan 3 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STIM1 | stromal interaction molecule 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TOR3A | torsin family 3, member A |
| TTLL7 | tubulin tyrosine ligase-like family member 7 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| VASH2 | vasohibin 2 |
| WDR76 | WD repeat domain 76 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WRB | tryptophan rich basic protein |
| XPA | xeroderma pigmentosum, complementation group A |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF197 | zinc finger protein 197 |
| ZNF253 | zinc finger protein 253 |
