| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the astemizole-6807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ARL14 | ADP-ribosylation factor-like 14 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD83 | CD83 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLGN | calmegin |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| EGR4 | early growth response 4 |
| EMID1 | EMI domain containing 1 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| ETV5 | ets variant 5 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HBEGF | heparin-binding EGF-like growth factor |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICAM1 | intercellular adhesion molecule 1 |
| IER2 | immediate early response 2 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNB1 | interferon, beta 1, fibroblast |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| IRF1 | interferon regulatory factor 1 |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| JUN | jun proto-oncogene |
| KDM6B | lysine (K)-specific demethylase 6B |
| KLF10 | Kruppel-like factor 10 |
| KLF2 | Kruppel-like factor 2 |
| KLF6 | Kruppel-like factor 6 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LDLR | low density lipoprotein receptor |
| LIF | leukemia inhibitory factor |
| LPIN1 | lipin 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MVD | mevalonate (diphospho) decarboxylase |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RND1 | Rho family GTPase 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC24D | SEC24 family member D |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| TAT | tyrosine aminotransferase |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIB1 | tribbles pseudokinase 1 |
| TRIB3 | tribbles pseudokinase 3 |
| TRIM2 | tripartite motif containing 2 |
| TXNIP | thioredoxin interacting protein |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| ZFP36 | ZFP36 ring finger protein |
| ZNF165 | zinc finger protein 165 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABHD17B | abhydrolase domain containing 17B |
| ACTL8 | actin-like 8 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| B3GNT1 | |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CACNA1D | calcium channel, voltage-dependent, L type, alpha 1D subunit |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNE2 | cyclin E2 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC25A | cell division cycle 25A |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSF1R | colony stimulating factor 1 receptor |
| CTPS1 | CTP synthase 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBF4B | DBF4 zinc finger B |
| DSPP | dentin sialophosphoprotein |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAN1 | FANCD2/FANCI-associated nuclease 1 |
| FOXI1 | forkhead box I1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPR27 | G protein-coupled receptor 27 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HOXC8 | homeobox C8 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IL20RA | interleukin 20 receptor, alpha |
| ITPKB | inositol-trisphosphate 3-kinase B |
| JMJD4 | jumonji domain containing 4 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| LOC729164 | hCG1732469 |
| LOC730101 | uncharacterized LOC730101 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LRRC49 | leucine rich repeat containing 49 |
| MEFV | Mediterranean fever |
| NCALD | neurocalcin delta |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCDHB3 | protocadherin beta 3 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PP14571 | uncharacterized LOC100130449 |
| PRF1 | perforin 1 (pore forming protein) |
| PRR14L | proline rich 14-like |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RGS19 | regulator of G-protein signaling 19 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| S100A4 | S100 calcium binding protein A4 |
| S100A9 | S100 calcium binding protein A9 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SH2D4A | SH2 domain containing 4A |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SNX15 | sorting nexin 15 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| ST5 | suppression of tumorigenicity 5 |
| TCTA | T-cell leukemia translocation altered |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM212 | transmembrane protein 212 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| UBOX5 | U-box domain containing 5 |
| UNC119 | unc-119 homolog (C. elegans) |
| ZNF134 | zinc finger protein 134 |
| ZNF573 | zinc finger protein 573 |
| ZNF574 | zinc finger protein 574 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
