asthma Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description A chronic respiratory disease manifested as difficulty breathing due to the narrowing of bronchial passageways.|Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.|A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).|A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, excercise, stress, reflux disease, medications, foods and emotional anxiety. (Experimental Factor Ontology, EFO_0000270)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0002099
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Genes

451 genes associated with the asthma phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
IL33R interleukin 33 receptor 2.95702
IL23R interleukin 23 receptor 2.69859
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 2.56875
LPP LIM domain containing preferred translocation partner in lipoma 2.40414
IL18RAP interleukin 18 receptor accessory protein 2.37936
EPDR1 ependymin related 1 2.37155
PROC protein C (inactivator of coagulation factors Va and VIIIa) 2.34145
IL18R1 interleukin 18 receptor 1 2.33605
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 2.3201
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 2.28874
KIAA1109 KIAA1109 2.15785
NOD2 nucleotide-binding oligomerization domain containing 2 2.08835
ZPBP2 zona pellucida binding protein 2 2.06607
GSDMB gasdermin B 2.06448
NOTCH4 notch 4 2.06445
IKZF3 IKAROS family zinc finger 3 (Aiolos) 2.05399
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 2.04964
CRP C-reactive protein, pentraxin-related 2.01032
ATXN2 ataxin 2 2.00018
IL1R1 interleukin 1 receptor, type I 1.94622
SH2B3 SH2B adaptor protein 3 1.90427
C5ORF56 chromosome 5 open reading frame 56 1.88591
GPR65 G protein-coupled receptor 65 1.87101
IL36R interleukin 36 receptor 1.85891
NKX2-3 NK2 homeobox 3 1.77862
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.76413
PBX2 pre-B-cell leukemia homeobox 2 1.74205
TAGAP T-cell activation RhoGTPase activating protein 1.73304
C6ORF10 chromosome 6 open reading frame 10 1.73304
EIF3E eukaryotic translation initiation factor 3, subunit E 1.69332
DUXA double homeobox A 1.64179
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3 1.63649
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.63258
LACC1 laccase (multicopper oxidoreductase) domain containing 1 1.61591
LOC100505718 1.61591
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 1.61591
PUS10 pseudouridylate synthase 10 1.59332
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.58488
GSDMA gasdermin A 1.57346
FGFR1OP FGFR1 oncogene partner 1.5645
MST1 macrophage stimulating 1 1.5645
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.52026
IL33 interleukin 33 1.51349
AKAP6 A kinase (PRKA) anchor protein 6 1.4986
CDK2 cyclin-dependent kinase 2 1.43716
STARD3 StAR-related lipid transfer (START) domain containing 3 1.42426
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 1.41863
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 1.40061
PTPN2 protein tyrosine phosphatase, non-receptor type 2 1.40061
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 1.38847
HNMT histamine N-methyltransferase 1.36794
ZMIZ1 zinc finger, MIZ-type containing 1 1.35901
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 1.35901
ITLN1 intelectin 1 (galactofuranose binding) 1.35521
NRG1 neuregulin 1 1.32793
ICOSLG inducible T-cell co-stimulator ligand 1.32793
RAD50 RAD50 homolog (S. cerevisiae) 1.31892
MMEL1 membrane metallo-endopeptidase-like 1 1.30781
SMAD3 SMAD family member 3 1.29507
PYHIN1 pyrin and HIN domain family, member 1 1.29386
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 1.28332
ICOS inducible T-cell co-stimulator 1.27347
PLEK pleckstrin 1.25845
LPIN2 lipin 2 1.25845
ARHGAP31 Rho GTPase activating protein 31 1.25845
PGAP3 post-GPI attachment to proteins 3 1.25654
ANTXR1 anthrax toxin receptor 1 1.24751
IL2RB interleukin 2 receptor, beta 1.24751
WDR36 WD repeat domain 36 1.24307
MED24 mediator complex subunit 24 1.22647
IL6R interleukin 6 receptor 1.21853
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 1.2142
PDE11A phosphodiesterase 11A 1.20966
PDE4D phosphodiesterase 4D, cAMP-specific 1.20811
WNT2 wingless-type MMTV integration site family member 2 1.19958
CCHCR1 coiled-coil alpha-helical rod protein 1 1.19766
UBE2QL1 ubiquitin-conjugating enzyme E2Q family-like 1 1.18936
HPSE2 heparanase 2 (inactive) 1.1784
NAV2 neuron navigator 2 1.17315
ABI3BP ABI family, member 3 (NESH) binding protein 1.17192
GAB1 GRB2-associated binding protein 1 1.16661
PSAP prosaposin 1.16177
RORA RAR-related orphan receptor A 1.15352
IL13 interleukin 13 1.15352
ERBB2 erb-b2 receptor tyrosine kinase 2 1.14804
FLCN folliculin 1.13911
DENND1B DENN/MADD domain containing 1B 1.12851
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 1.12851
PPP1R12B protein phosphatase 1, regulatory subunit 12B 1.1251
EPHA5 EPH receptor A5 1.12351
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 1.11669
TCAP titin-cap 1.11592
BTNL2 butyrophilin-like 2 1.11487
KLHL5 kelch-like family member 5 1.11203
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 1.10889
PRKG1 protein kinase, cGMP-dependent, type I 1.08774
SRP9 signal recognition particle 9kDa 1.08287
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 1.0799
LRRC3C leucine rich repeat containing 3C 1.07834
TIMP2 TIMP metallopeptidase inhibitor 2 1.07729
ATRNL1 attractin-like 1 1.06824
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 1.05938
LRP2BP LRP2 binding protein 1.05296
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 1.05104
BOC BOC cell adhesion associated, oncogene regulated 1.05104
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 1.0471
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 1.04429
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 1.04365
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 1.04365
PADI2 peptidyl arginine deiminase, type II 1.03165
PNMT phenylethanolamine N-methyltransferase 1.03165
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 1.02775
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4 1.02729
LOC643542 uncharacterized LOC643542 1.02374
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 1.02374
PCNXL2 pecanex-like 2 (Drosophila) 1.02247
PDZRN4 PDZ domain containing ring finger 4 1.01617
FAM102B family with sequence similarity 102, member B 1.01418
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 1.00123
ATP11AUN ATP11A upstream neighbor 1.00091
ATG3 autophagy related 3 1.00059
AGFG1 ArfGAP with FG repeats 1 1.00059
TMEM132B transmembrane protein 132B 0.998412
NOS2 nitric oxide synthase 2, inducible 0.995928
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.994551
PLA1A phospholipase A1 member A 0.986268
CAMTA1 calmodulin binding transcription activator 1 0.98364
KIAA0825 KIAA0825 0.98364
PXYLP1 2-phosphoxylose phosphatase 1 0.981095
OXR1 oxidation resistance 1 0.977911
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.977911
LOC100287329 uncharacterized LOC100287329 0.969694
GJA1 gap junction protein, alpha 1, 43kDa 0.969142
TNXB tenascin XB 0.969142
STARD13 StAR-related lipid transfer (START) domain containing 13 0.969142
DCLK1 doublecortin-like kinase 1 0.969142
ALK anaplastic lymphoma receptor tyrosine kinase 0.969142
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.967782
SORCS1 sortilin-related VPS10 domain containing receptor 1 0.966449
CDHR3 cadherin-related family member 3 0.963857
SLC22A23 solute carrier family 22, member 23 0.963857
ERBB3 erb-b2 receptor tyrosine kinase 3 0.961266
RIMS1 regulating synaptic membrane exocytosis 1 0.957533
SOCS6 suppressor of cytokine signaling 6 0.957533
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.956975
ADRA1B adrenoceptor alpha 1B 0.953437
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14 0.95082
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1 0.942765
ACO1 aconitase 1, soluble 0.942765
ZNF665 zinc finger protein 665 0.942765
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.942765
IGHMBP2 immunoglobulin mu binding protein 2 0.940413
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.940153
PGM2 phosphoglucomutase 2 0.937096
ACE angiotensin I converting enzyme 0.930595
SPATS2L spermatogenesis associated, serine-rich 2-like 0.926083
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 0.919744
IGSF3 immunoglobulin superfamily, member 3 0.919744
KANK1 KN motif and ankyrin repeat domains 1 0.919338
CDH13 cadherin 13 0.90455
WDR27 WD repeat domain 27 0.90455
NFIA nuclear factor I/A 0.903226
EFCAB6 EF-hand calcium binding domain 6 0.901186
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.899912
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3 0.899912
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.899912
GRM5 glutamate receptor, metabotropic 5 0.899372
VMP1 vacuole membrane protein 1 0.898124
TMEM61 transmembrane protein 61 0.897947
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.891813
TSHR thyroid stimulating hormone receptor 0.890508
ZNF804B zinc finger protein 804B 0.886418
MYO7B myosin VIIB 0.882984
NRG3 neuregulin 3 0.882984
PRKCQ protein kinase C, theta 0.882984
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.882984
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.881236
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.871842
WDR25 WD repeat domain 25 0.871842
HRASLS5 HRAS-like suppressor family, member 5 0.871842
SNTG2 syntrophin, gamma 2 0.869196
TLN1 talin 1 0.868241
ZNF71 zinc finger protein 71 0.868241
SYNPO2 synaptopodin 2 0.868241
MAVS mitochondrial antiviral signaling protein 0.868241
MACROD2 MACRO domain containing 2 0.868241
PTPRU protein tyrosine phosphatase, receptor type, U 0.867835
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.855449
COL22A1 collagen, type XXII, alpha 1 0.855449
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.855449
UNC79 unc-79 homolog (C. elegans) 0.855449
XPR1 xenotropic and polytropic retrovirus receptor 1 0.855449
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.85426
AKAP12 A kinase (PRKA) anchor protein 12 0.851129
ZMYND8 zinc finger, MYND-type containing 8 0.850449
TSNARE1 t-SNARE domain containing 1 0.849774
CSMD1 CUB and Sushi multiple domains 1 0.849662
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.849104
CD82 CD82 molecule 0.849104
STYK1 serine/threonine/tyrosine kinase 1 0.848439
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.844241
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.837193
ULK4 unc-51 like kinase 4 0.834343
DOCK2 dedicator of cytokinesis 2 0.834343
RFC4 replication factor C (activator 1) 4, 37kDa 0.834343
ARHGAP8 Rho GTPase activating protein 8 0.831588
KIF18B kinesin family member 18B 0.831588
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.82634
SYNPR synaptoporin 0.825497
ITGB5 integrin, beta 5 0.817516
ZNF772 zinc finger protein 772 0.81297
LINC00466 long intergenic non-protein coding RNA 466 0.812214
YTHDC1 YTH domain containing 1 0.810722
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.809986
SEZ6L seizure related 6 homolog (mouse)-like 0.809986
TTC7A tetratricopeptide repeat domain 7A 0.80501
GLIS3 GLIS family zinc finger 3 0.801631
DNAH12 dynein, axonemal, heavy chain 12 0.799025
IPCEF1 interaction protein for cytohesin exchange factors 1 0.798387
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.790435
MGC27382 uncharacterized MGC27382 0.790435
TNIP1 TNFAIP3 interacting protein 1 0.785384
PTPRD protein tyrosine phosphatase, receptor type, D 0.785384
RAB39A RAB39A, member RAS oncogene family 0.781779
ADGB androglobin 0.772842
KIAA0922 KIAA0922 0.771787
XYLT1 xylosyltransferase I 0.768197
CTNND2 catenin (cadherin-associated protein), delta 2 0.766703
SULF1 sulfatase 1 0.765174
CDYL chromodomain protein, Y-like 0.764079
TTLL9 tubulin tyrosine ligase-like family member 9 0.762459
BCAR3 breast cancer anti-estrogen resistance 3 0.760343
EFCAB14 EF-hand calcium binding domain 14 0.759303
SYN3 synapsin III 0.757765
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.755753
NMU neuromedin U 0.754763
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.752335
BARX2 BARX homeobox 2 0.74997
KIAA0930 KIAA0930 0.748581
NOP14 NOP14 nucleolar protein 0.747666
LOC100507377 uncharacterized LOC100507377 0.747666
SLC12A9 solute carrier family 12, member 9 0.747666
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.745864
RAB5B RAB5B, member RAS oncogene family 0.744976
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.74151
FSTL4 follistatin-like 4 0.739827
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.739827
HLA-DRA major histocompatibility complex, class II, DR alpha 0.734535
HS1BP3 HCLS1 binding protein 3 0.731489
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.726891
SCHIP1 schwannomin interacting protein 1 0.725675
PARVB parvin, beta 0.724872
ZNF585B zinc finger protein 585B 0.723288
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.722505
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 0.722116
TMEM132D transmembrane protein 132D 0.722116
SOX5 SRY (sex determining region Y)-box 5 0.721344
NTNG1 netrin G1 0.720196
PAX3 paired box 3 0.719817
CA10 carbonic anhydrase X 0.719063
MYLK myosin light chain kinase 0.718314
ASTN2 astrotactin 2 0.718314
FER1L6 fer-1-like family member 6 0.71647
TGFB1 transforming growth factor, beta 1 0.714661
DOCK10 dedicator of cytokinesis 10 0.714303
RYR2 ryanodine receptor 2 (cardiac) 0.714303
CPNE4 copine IV 0.713947
MYH4 myosin, heavy chain 4, skeletal muscle 0.712186
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.711145
TTC27 tetratricopeptide repeat domain 27 0.710458
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.709765
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.707523
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.705692
KALRN kalirin, RhoGEF kinase 0.705692
FRMD4A FERM domain containing 4A 0.704609
LRRC4C leucine rich repeat containing 4C 0.701779
USP47 ubiquitin specific peptidase 47 0.699367
FSIP1 fibrous sheath interacting protein 1 0.698015
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 0.695039
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19 0.694067
ADGRB3 adhesion G protein-coupled receptor B3 0.691836
LRRC3B leucine rich repeat containing 3B 0.690584
NTM neurotrimin 0.690584
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.687825
ZNF423 zinc finger protein 423 0.686325
STK32A serine/threonine kinase 32A 0.686325
ADORA1 adenosine A1 receptor 0.686325
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 0.684556
LOC100506023 uncharacterized LOC100506023 0.684265
COL5A3 collagen, type V, alpha 3 0.682533
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 0.681114
PDE9A phosphodiesterase 9A 0.679051
POLI polymerase (DNA directed) iota 0.678743
CPM carboxypeptidase M 0.67722
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.676917
LINC01194 long intergenic non-protein coding RNA 1194 0.676017
FIG4 FIG4 phosphoinositide 5-phosphatase 0.674238
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.672779
ABLIM1 actin binding LIM protein 1 0.671056
PCDH15 protocadherin-related 15 0.669642
LRP1B low density lipoprotein receptor-related protein 1B 0.664442
OR2C1 olfactory receptor, family 2, subfamily C, member 1 0.663117
HPN hepsin 0.662592
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa 0.662592
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.661809
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.660006
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.659244
GNG4 guanine nucleotide binding protein (G protein), gamma 4 0.656743
GCK glucokinase (hexokinase 4) 0.65576
SWI5 SWI5 recombination repair homolog (yeast) 0.655516
TMCO4 transmembrane and coiled-coil domains 4 0.654304
BEND5 BEN domain containing 5 0.654304
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.652159
MTMR6 myotubularin related protein 6 0.651923
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.648629
GLB1L3 galactosidase, beta 1-like 3 0.64787
BEST1 bestrophin 1 0.645871
FOXP1 forkhead box P1 0.645131
PHACTR2 phosphatase and actin regulator 2 0.639858
SORBS2 sorbin and SH3 domain containing 2 0.639858
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) 0.639391
ATP9A ATPase, class II, type 9A 0.639391
LOC100506985 uncharacterized LOC100506985 0.637546
MTUS2 microtubule associated tumor suppressor candidate 2 0.636635
FSTL5 follistatin-like 5 0.635061
SIRAL2 SIR2 antiphage like 2 0.634393
TMBIM4 transmembrane BAX inhibitor motif containing 4 0.632852
SMC1B structural maintenance of chromosomes 1B 0.632852
CGN cingulin 0.632634
GSTA4 glutathione S-transferase alpha 4 0.632416
ADCY9 adenylate cyclase 9 0.631981
LOC441204 uncharacterized LOC441204 0.631765
DPY19L1P1 DPY19L1 pseudogene 1 0.631549
C1ORF21 chromosome 1 open reading frame 21 0.630049
LBH limb bud and heart development 0.629625
AKAP13 A kinase (PRKA) anchor protein 13 0.628991
CACUL1 CDK2-associated, cullin domain 1 0.628571
HS3ST4 heparan sulfate (glucosamine) 3-O-sulfotransferase 4 0.627736
MSRA methionine sulfoxide reductase A 0.627528
LAMA1 laminin, alpha 1 0.627114
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.626701
PLXDC2 plexin domain containing 2 0.626701
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.626086
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.625881
AGGF1 angiogenic factor with G patch and FHA domains 1 0.622863
FAM160B1 family with sequence similarity 160, member B1 0.62227
MPPED2 metallophosphoesterase domain containing 2 0.622073
NECAB2 N-terminal EF-hand calcium binding protein 2 0.622073
PKP1 plakophilin 1 0.620511
OSMR oncostatin M receptor 0.618024
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.617271
ERICH1 glutamate-rich 1 0.616505
PTPRT protein tyrosine phosphatase, receptor type, T 0.616505
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.616311
CARM1 coactivator-associated arginine methyltransferase 1 0.615926
THBS4 thrombospondin 4 0.615351
CD28 CD28 molecule 0.614589
DNER delta/notch-like EGF repeat containing 0.612709
EYA2 EYA transcriptional coactivator and phosphatase 2 0.612523
AUTS2 autism susceptibility candidate 2 0.612337
CREB5 cAMP responsive element binding protein 5 0.611781
ADCY2 adenylate cyclase 2 (brain) 0.610862
RASSF2 Ras association (RalGDS/AF-6) domain family member 2 0.60977
CPVL carboxypeptidase, vitellogenic-like 0.609589
REPS1 RALBP1 associated Eps domain containing 1 0.609048
C19ORF38 chromosome 19 open reading frame 38 0.607443
CCDC140 coiled-coil domain containing 140 0.605862
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.602943
ZEB1 zinc finger E-box binding homeobox 1 0.601932
GREM2 gremlin 2, DAN family BMP antagonist 0.601097
TMEM161B transmembrane protein 161B 0.598959
HLA-F-AS1 HLA-F antisense RNA 1 0.598311
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.597506
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.596866
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5 0.596707
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 0.596389
STAT4 signal transducer and activator of transcription 4 0.596389
SGCZ sarcoglycan, zeta 0.595915
TMEM62 transmembrane protein 62 0.595757
DMRT3 doublesex and mab-3 related transcription factor 3 0.59466
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.593729
TMEM237 transmembrane protein 237 0.591439
RBBP5 retinoblastoma binding protein 5 0.591138
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 0.590389
NPAS3 neuronal PAS domain protein 3 0.590091
C10ORF11 chromosome 10 open reading frame 11 0.587883
IRF2 interferon regulatory factor 2 0.587014
RBM18 RNA binding motif protein 18 0.585259
ASIC2 acid sensing (proton gated) ion channel 2 0.585012
KAT2B K(lysine) acetyltransferase 2B 0.58452
PTPRR protein tyrosine phosphatase, receptor type, R 0.584275
ANLN anillin, actin binding protein 0.583908
FAM149A family with sequence similarity 149, member A 0.582578
TRAF3IP3 TRAF3 interacting protein 3 0.581861
UBASH3A ubiquitin associated and SH3 domain containing A 0.580678
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.580678
ZSCAN31 zinc finger and SCAN domain containing 31 0.578819
LOC400794 uncharacterized LOC400794 0.577677
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 0.57745
MEIS2 Meis homeobox 2 0.576661
MAPK10 mitogen-activated protein kinase 10 0.576326
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 0.574995
EIF3D eukaryotic translation initiation factor 3, subunit D 0.573361
NCAM2 neural cell adhesion molecule 2 0.572823
TACR3 tachykinin receptor 3 0.572823
LRRC28 leucine rich repeat containing 28 0.572823
GYS2 glycogen synthase 2 (liver) 0.570703
NIN ninein (GSK3B interacting protein) 0.56762
RABGAP1L RAB GTPase activating protein 1-like 0.562717
SBNO2 strawberry notch homolog 2 (Drosophila) 0.55536
LOC100506664 uncharacterized LOC100506664 0.55536
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.549174
SCARB1 scavenger receptor class B, member 1 0.543523
SLC45A2 solute carrier family 45, member 2 0.543523
SPTBN1 spectrin, beta, non-erythrocytic 1 0.535185
PI16 peptidase inhibitor 16 0.535185
CNGB1 cyclic nucleotide gated channel beta 1 0.528162
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.522136
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.522136
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.516758
ENAH enabled homolog (Drosophila) 0.486163
TMEM140 transmembrane protein 140 0.481126
RAB14 RAB14, member RAS oncogene family 0.481126
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.479543
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 0.474474
SBF1 SET binding factor 1 0.4604
GLI3 GLI family zinc finger 3 0.449892
OXTR oxytocin receptor 0.447818
ESR1 estrogen receptor 1 0.44484
GLCCI1 glucocorticoid induced 1 0.443881
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.443208
LRP2 low density lipoprotein receptor-related protein 2 0.43784
CRHBP corticotropin releasing hormone binding protein 0.430267
SGSM1 small G protein signaling modulator 1 0.416187
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.413807
DCAF4 DDB1 and CUL4 associated factor 4 0.401355
TSC1 tuberous sclerosis 1 0.395466
CEP68 centrosomal protein 68kDa 0.391503
FILIP1 filamin A interacting protein 1 0.391503
LRRC43 leucine rich repeat containing 43 0.388393
PDZD2 PDZ domain containing 2 0.388393
CIITA class II, major histocompatibility complex, transactivator 0.388393
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.385578
ENPP5 ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) 0.385578
AK8 adenylate kinase 8 0.383187
ZFYVE1 zinc finger, FYVE domain containing 1 0.381803
DCDC2 doublecortin domain containing 2 0.381605
C6 complement component 6 0.381276
ILVBL ilvB (bacterial acetolactate synthase)-like 0.379626
RBM25 RNA binding motif protein 25 0.375166
MEIS1 Meis homeobox 1 0.356183