asymmetric synapse Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. (Gene Ontology, GO_0032279)
External Link http://amigo.geneontology.org/amigo/term/GO:0032279
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Genes

132 proteins localized to the asymmetric synapse cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ABI3 ABI family, member 3
ADCY8 adenylate cyclase 8 (brain)
ADD1 adducin 1 (alpha)
ADD2 adducin 2 (beta)
ADD3 adducin 3 (gamma)
ADGRA1 adhesion G protein-coupled receptor A1
ADGRB1 adhesion G protein-coupled receptor B1
AKAP5 A kinase (PRKA) anchor protein 5
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP32 Rho GTPase activating protein 32
ARHGAP44 Rho GTPase activating protein 44
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
CABP1 calcium binding protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CACNG8 calcium channel, voltage-dependent, gamma subunit 8
CAMK1 calcium/calmodulin-dependent protein kinase I
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2D calcium/calmodulin-dependent protein kinase II delta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CDK5 cyclin-dependent kinase 5
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CNIH2 cornichon family AMPA receptor auxiliary protein 2
CORIN corin, serine peptidase
CPEB4 cytoplasmic polyadenylation element binding protein 4
CRIPT cysteine-rich PDZ-binding protein
CTNND2 catenin (cadherin-associated protein), delta 2
DISC1 disrupted in schizophrenia 1
DLG5 discs, large homolog 5 (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DNM2 dynamin 2
DNM3 dynamin 3
DTNB dystrobrevin, beta
DTNBP1 dystrobrevin binding protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM81A family with sequence similarity 81, member A
FMR1 fragile X mental retardation 1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAP43 growth associated protein 43
GPER1 G protein-coupled estrogen receptor 1
GPHN gephyrin
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRM7 glutamate receptor, metabotropic 7
HIP1R huntingtin interacting protein 1 related
HOMER1 homer scaffolding protein 1
HOMER2 homer scaffolding protein 2
HOMER3 homer scaffolding protein 3
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INSYN1 inhibitory synaptic factor 1
INSYN2A inhibitory synaptic factor 2A
IQSEC3 IQ motif and Sec7 domain 3
KALRN kalirin, RhoGEF kinase
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRC7 leucine rich repeat containing 7
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTMR2 myotubularin related protein 2
NANOS1 nanos homolog 1 (Drosophila)
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NEURL1 neuralized E3 ubiquitin protein ligase 1
NLGN1 neuroligin 1
NLGN3 neuroligin 3
NLGN4X neuroligin 4, X-linked
NLGN4Y neuroligin 4, Y-linked
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PDLIM5 PDZ and LIM domain 5
PICK1 protein interacting with PRKCA 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PRNP prion protein
PTK2B protein tyrosine kinase 2 beta
RGS14 regulator of G-protein signaling 14
RHEB Ras homolog enriched in brain
RNF112 ring finger protein 112
RPL12 ribosomal protein L12
RPL14 ribosomal protein L14
RPL30 ribosomal protein L30
RPL38 ribosomal protein L38
RPL7 ribosomal protein L7
RPL8 ribosomal protein L8
RPLP0 ribosomal protein, large, P0
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS25 ribosomal protein S25
RPS27 ribosomal protein S27
RPS3 ribosomal protein S3
RTN1 reticulon 1
RTN2 reticulon 2
RTN3 reticulon 3
RTN4 reticulon 4
SAMD14 sterile alpha motif domain containing 14
SCRIB scribbled planar cell polarity protein
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SH2D5 SH2 domain containing 5
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHANK3 SH3 and multiple ankyrin repeat domains 3
SHISA6 shisa family member 6
SHISA7 shisa family member 7
SHISA8 shisa family member 8
SHISA9 shisa family member 9
SIGMAR1 sigma non-opioid intracellular receptor 1
SIPA1L1 signal-induced proliferation-associated 1 like 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8A2 solute carrier family 8 (sodium/calcium exchanger), member 2
SLC8A3 solute carrier family 8 (sodium/calcium exchanger), member 3
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SRCIN1 SRC kinase signaling inhibitor 1
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
STRN striatin, calmodulin binding protein
SYNDIG1 synapse differentiation inducing 1
SYT12 synaptotagmin XII
TMEM108 transmembrane protein 108
TSC2 tuberous sclerosis 2
USP50 ubiquitin specific peptidase 50
USP8 ubiquitin specific peptidase 8
ZDHHC2 zinc finger, DHHC-type containing 2