atelectasis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Collapse of part of a lung associated with absence of inflation (air) of that part. (Human Phenotype Ontology, HP_0100750)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001177
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Genes

86 gene mutations causing the atelectasis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADA adenosine deaminase
ADRA2B adrenoceptor alpha 2B
AGRN agrin
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLEC1B C-type lectin domain family 1, member B
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DHCR7 7-dehydrocholesterol reductase
DMRT2 doublesex and mab-3 related transcription factor 2
DOCK1 dedicator of cytokinesis 1
DPH1 diphthamide biosynthesis 1
DPPA4 developmental pluripotency associated 4
ECEL1 endothelin converting enzyme-like 1
EGFR epidermal growth factor receptor
ELN elastin
EPAS1 endothelial PAS domain protein 1
FBXW8 F-box and WD repeat domain containing 8
FOXC2 forkhead box C2
FSTL1 follistatin-like 1
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HAT1 histone acetyltransferase 1
HCK HCK proto-oncogene, Src family tyrosine kinase
HELLS helicase, lymphoid-specific
HHIP hedgehog interacting protein
HMGB1 high mobility group box 1
HOXA5 homeobox A5
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IMPAD1 inositol monophosphatase domain containing 1
ITGA8 integrin, alpha 8
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KDM6A lysine (K)-specific demethylase 6A
KIF5A kinesin family member 5A
LHX4 LIM homeobox 4
LOX lysyl oxidase
LPCAT1 lysophosphatidylcholine acyltransferase 1
LPL lipoprotein lipase
LRP2 low density lipoprotein receptor-related protein 2
LRP4 low density lipoprotein receptor-related protein 4
LTBP4 latent transforming growth factor beta binding protein 4
LYST lysosomal trafficking regulator
MADD MAP-kinase activating death domain
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK6 mitogen-activated protein kinase 6
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MNX1 motor neuron and pancreas homeobox 1
NABP2 nucleic acid binding protein 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFIB nuclear factor I/B
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PDGFA platelet-derived growth factor alpha polypeptide
PDPN podoplanin
PLAGL1 pleiomorphic adenoma gene-like 1
POLB polymerase (DNA directed), beta
PROP1 PROP paired-like homeobox 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
RC3H1 ring finger and CCCH-type domains 1
SC5D sterol-C5-desaturase
SFTPB surfactant protein B
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLIT3 slit homolog 3 (Drosophila)
SNX5 sorting nexin 5
STK40 serine/threonine kinase 40
SYK spleen tyrosine kinase
SYNE1 spectrin repeat containing, nuclear envelope 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TH tyrosine hydroxylase
TMEM38B transmembrane protein 38B
TRPS1 trichorhinophalangeal syndrome I
TSHZ3 teashirt zinc finger homeobox 3
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1