| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the atovaquone-2480 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| APOC4 | apolipoprotein C-IV |
| AQP9 | aquaporin 9 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| B9D1 | B9 protein domain 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CCDC57 | coiled-coil domain containing 57 |
| CCR9 | chemokine (C-C motif) receptor 9 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CFAP69 | cilia and flagella associated protein 69 |
| CFAP70 | cilia and flagella associated protein 70 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHN2 | chimerin 2 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DES | desmin |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| ELAC2 | elaC ribonuclease Z 2 |
| FAAH | fatty acid amide hydrolase |
| FRY | furry homolog (Drosophila) |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR22 | G protein-coupled receptor 22 |
| GRM6 | glutamate receptor, metabotropic 6 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IGKV3-20 | immunoglobulin kappa variable 3-20 |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL24 | interleukin 24 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA1654 | KIAA1654 protein |
| KIF1A | kinesin family member 1A |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT15 | keratin 15, type I |
| KRT6B | keratin 6B, type II |
| LDB3 | LIM domain binding 3 |
| LIG3 | ligase III, DNA, ATP-dependent |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MEF2C | myocyte enhancer factor 2C |
| MFAP3L | microfibrillar-associated protein 3-like |
| MGC2889 | uncharacterized protein MGC2889 |
| MISP | mitotic spindle positioning |
| MLF1 | myeloid leukemia factor 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MPPE1 | metallophosphoesterase 1 |
| MTAP | methylthioadenosine phosphorylase |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NINJ2 | ninjurin 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OLFML2B | olfactomedin-like 2B |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| OSM | oncostatin M |
| PADI1 | peptidyl arginine deiminase, type I |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHF3 | PHD finger protein 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POU2F2 | POU class 2 homeobox 2 |
| PTCRA | pre T-cell antigen receptor alpha |
| PYHIN1 | pyrin and HIN domain family, member 1 |
| RAB3D | RAB3D, member RAS oncogene family |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RGS10 | regulator of G-protein signaling 10 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RRBP1 | ribosome binding protein 1 |
| RTCA | RNA 3'-terminal phosphate cyclase |
| S100A11 | S100 calcium binding protein A11 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SLC35F5 | solute carrier family 35, member F5 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| STK24 | serine/threonine kinase 24 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TPD52L1 | tumor protein D52-like 1 |
| TRGV5 | T cell receptor gamma variable 5 |
| TSKS | testis-specific serine kinase substrate |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADM | adrenomedullin |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| APOL6 | apolipoprotein L, 6 |
| ARG1 | arginase 1 |
| ART1 | ADP-ribosyltransferase 1 |
| ATF3 | activating transcription factor 3 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like |
| BTG2 | BTG family, member 2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CCNE2 | cyclin E2 |
| CCNT1 | cyclin T1 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD1D | CD1d molecule |
| CD69 | CD69 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| FANCE | Fanconi anemia, complementation group E |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FOXD1 | forkhead box D1 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GPR19 | G protein-coupled receptor 19 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H2AG | histone cluster 1, H2ag |
| ICAM5 | intercellular adhesion molecule 5, telencephalin |
| INCENP | inner centromere protein antigens 135/155kDa |
| INSIG2 | insulin induced gene 2 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KLF10 | Kruppel-like factor 10 |
| KRCC1 | lysine-rich coiled-coil 1 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MID1IP1 | MID1 interacting protein 1 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NDRG1 | N-myc downstream regulated 1 |
| NFE2 | nuclear factor, erythroid 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PANX1 | pannexin 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDE6H | phosphodiesterase 6H, cGMP-specific, cone, gamma |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PLCD1 | phospholipase C, delta 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PORCN | porcupine homolog (Drosophila) |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PYGB | phosphorylase, glycogen; brain |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB33B | RAB33B, member RAS oncogene family |
| RGS13 | regulator of G-protein signaling 13 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS2 | regulator of G-protein signaling 2 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SLA | Src-like-adaptor |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SPP1 | secreted phosphoprotein 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| STC2 | stanniocalcin 2 |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D19 | TBC1 domain family, member 19 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM45A | transmembrane protein 45A |
| TNF | tumor necrosis factor |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPAN5 | tetraspanin 5 |
| TUBA3C | tubulin, alpha 3c |
| TXNIP | thioredoxin interacting protein |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VGLL4 | vestigial-like family member 4 |
| ZC3H4 | zinc finger CCCH-type containing 4 |
| ZNF10 | zinc finger protein 10 |
| ZNF292 | zinc finger protein 292 |
| ZNF395 | zinc finger protein 395 |
