| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the atovaquone-4201 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCK2 | aarF domain containing kinase 2 |
| ADRB3 | adrenoceptor beta 3 |
| AIRE | autoimmune regulator |
| AK5 | adenylate kinase 5 |
| ART1 | ADP-ribosyltransferase 1 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CDH19 | cadherin 19, type 2 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLEC4E | C-type lectin domain family 4, member E |
| CLIC5 | chloride intracellular channel 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| COMMD4 | COMM domain containing 4 |
| CYHR1 | cysteine/histidine-rich 1 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DRD2 | dopamine receptor D2 |
| DTNA | dystrobrevin, alpha |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EGR1 | early growth response 1 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FOXN3 | forkhead box N3 |
| FPR1 | formyl peptide receptor 1 |
| FRMD1 | FERM domain containing 1 |
| FRMD4B | FERM domain containing 4B |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GPR182 | G protein-coupled receptor 182 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| HAP1 | huntingtin-associated protein 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| KIF13A | kinesin family member 13A |
| LCMT2 | leucine carboxyl methyltransferase 2 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LINC00312 | long intergenic non-protein coding RNA 312 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MEF2D | myocyte enhancer factor 2D |
| MEFV | Mediterranean fever |
| MFAP5 | microfibrillar associated protein 5 |
| MMP25 | matrix metallopeptidase 25 |
| MMP3 | matrix metallopeptidase 3 |
| MST1 | macrophage stimulating 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NDRG2 | NDRG family member 2 |
| NF1 | neurofibromin 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NRP1 | neuropilin 1 |
| OAZ3 | ornithine decarboxylase antizyme 3 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OSR2 | odd-skipped related transciption factor 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PKP4 | plakophilin 4 |
| PLCH2 | phospholipase C, eta 2 |
| PLK4 | polo-like kinase 4 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PNMA3 | paraneoplastic Ma antigen 3 |
| PON1 | paraoxonase 1 |
| RANBP1 | RAN binding protein 1 |
| RARB | retinoic acid receptor, beta |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RETN | resistin |
| RGS5 | regulator of G-protein signaling 5 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SATB2 | SATB homeobox 2 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLCO4C1 | solute carrier organic anion transporter family, member 4C1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SPEG | SPEG complex locus |
| SSTR5 | somatostatin receptor 5 |
| STX7 | syntaxin 7 |
| SYCP1 | synaptonemal complex protein 1 |
| TBRG4 | transforming growth factor beta regulator 4 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRIM10 | tripartite motif containing 10 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UTS2 | urotensin 2 |
| VWA5A | von Willebrand factor A domain containing 5A |
| WNK1 | WNK lysine deficient protein kinase 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZIM2 | zinc finger, imprinted 2 |
| ZNF287 | zinc finger protein 287 |
| ZNF334 | zinc finger protein 334 |
| ZNF343 | zinc finger protein 343 |
| ZNF639 | zinc finger protein 639 |
| ZNF688 | zinc finger protein 688 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACE | angiotensin I converting enzyme |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CAPN15 | calpain 15 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CBX8 | chromobox homolog 8 |
| CCDC106 | coiled-coil domain containing 106 |
| CCNT1 | cyclin T1 |
| CD68 | CD68 molecule |
| CLDN1 | claudin 1 |
| CORO1A | coronin, actin binding protein, 1A |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DMTN | dematin actin binding protein |
| DSPP | dentin sialophosphoprotein |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FLJ21369 | uncharacterized protein FLJ21369 |
| FOXA1 | forkhead box A1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H2BN | histone cluster 1, H2bn |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC13 | homeobox C13 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KIAA0319L | KIAA0319-like |
| KIAA1456 | KIAA1456 |
| KLF13 | Kruppel-like factor 13 |
| KRT20 | keratin 20, type I |
| KRT86 | keratin 86, type II |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LOC100287590 | uncharacterized LOC100287590 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MGP | matrix Gla protein |
| MTCP1 | mature T-cell proliferation 1 |
| MTSS1L | metastasis suppressor 1-like |
| MVP | major vault protein |
| MXRA8 | matrix-remodelling associated 8 |
| MYL9 | myosin, light chain 9, regulatory |
| MYO1F | myosin IF |
| NARFL | nuclear prelamin A recognition factor-like |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NOTCH1 | notch 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| PCDH12 | protocadherin 12 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCIN | scinderin |
| SLN | sarcolipin |
| STEAP4 | STEAP family member 4 |
| STIM1 | stromal interaction molecule 1 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN1 | talin 1 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNS2 | tensin 2 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TUBA3C | tubulin, alpha 3c |
| VEGFB | vascular endothelial growth factor B |
| ZNF205 | zinc finger protein 205 |
| ZNF408 | zinc finger protein 408 |
| ZNF574 | zinc finger protein 574 |
| ZNF667 | zinc finger protein 667 |
| ZYX | zyxin |