atractyloside-3695 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the atractyloside-3695 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACVR1B activin A receptor, type IB
ADAM23 ADAM metallopeptidase domain 23
ADRBK2 adrenergic, beta, receptor kinase 2
ANAPC13 anaphase promoting complex subunit 13
ARSA arylsulfatase A
ATP11A ATPase, class VI, type 11A
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
BMP7 bone morphogenetic protein 7
C10ORF12 chromosome 10 open reading frame 12
C19ORF26 chromosome 19 open reading frame 26
CA5B carbonic anhydrase VB, mitochondrial
CARF calcium responsive transcription factor
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC30 coiled-coil domain containing 30
CD53 CD53 molecule
CD58 CD58 molecule
CDRT1 CMT1A duplicated region transcript 1
CELP carboxyl ester lipase pseudogene
CEND1 cell cycle exit and neuronal differentiation 1
CLIC5 chloride intracellular channel 5
CLPS colipase, pancreatic
CRAT carnitine O-acetyltransferase
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
EFNB3 ephrin-B3
EGFR epidermal growth factor receptor
EPHA5 EPH receptor A5
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EXPH5 exophilin 5
F5 coagulation factor V (proaccelerin, labile factor)
FAS Fas cell surface death receptor
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FN1 fibronectin 1
FRMD1 FERM domain containing 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GM2A GM2 ganglioside activator
GRM2 glutamate receptor, metabotropic 2
HCFC1 host cell factor C1
HIST1H4F histone cluster 1, H4f
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HPCAL4 hippocalcin like 4
IGF2-AS IGF2 antisense RNA
IL21R interleukin 21 receptor
IL2RB interleukin 2 receptor, beta
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IZUMO4 IZUMO family member 4
KAT2A K(lysine) acetyltransferase 2A
KAZN kazrin, periplakin interacting protein
KIF25 kinesin family member 25
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KSR1 kinase suppressor of ras 1
LIPE lipase, hormone-sensitive
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MNMIP1 manchette microtubule inner protein 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MYO15A myosin XVA
MYOZ1 myozenin 1
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPTXR neuronal pentraxin receptor
NRXN3 neurexin 3
NSUN7 NOP2/Sun domain family, member 7
NTF3 neurotrophin 3
OXCT2 3-oxoacid CoA transferase 2
PBX1 pre-B-cell leukemia homeobox 1
PCDH11X protocadherin 11 X-linked
PCDHGA10 protocadherin gamma subfamily A, 10
PGAP3 post-GPI attachment to proteins 3
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
RAD50 RAD50 homolog (S. cerevisiae)
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS4 regulator of G-protein signaling 4
RHAG Rh-associated glycoprotein
RPL10L ribosomal protein L10-like
RUNDC3A RUN domain containing 3A
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SLC17A2 solute carrier family 17, member 2
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SOX3 SRY (sex determining region Y)-box 3
TACC1 transforming, acidic coiled-coil containing protein 1
TBC1D30 TBC1 domain family, member 30
TGFA transforming growth factor, alpha
THRB thyroid hormone receptor, beta
TK2 thymidine kinase 2, mitochondrial
TNS1 tensin 1
TSKS testis-specific serine kinase substrate
VSX1 visual system homeobox 1
WNT16 wingless-type MMTV integration site family, member 16
ZFP64 ZFP64 zinc finger protein
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRL2 adhesion G protein-coupled receptor L2
AGO4 argonaute RISC catalytic component 4
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALPK3 alpha-kinase 3
AMT aminomethyltransferase
ANP32A-IT1 ANP32A intronic transcript 1
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
ARC activity-regulated cytoskeleton-associated protein
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
ARRB2 arrestin, beta 2
BMP15 bone morphogenetic protein 15
C17ORF53 chromosome 17 open reading frame 53
C1ORF21 chromosome 1 open reading frame 21
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA9 carbonic anhydrase IX
CCDC71 coiled-coil domain containing 71
CDK20 cyclin-dependent kinase 20
CEP41 centrosomal protein 41kDa
CLEC4E C-type lectin domain family 4, member E
CLTCL1 clathrin, heavy chain-like 1
CNTN1 contactin 1
COL16A1 collagen, type XVI, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CORO2B coronin, actin binding protein, 2B
CREB5 cAMP responsive element binding protein 5
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DIO3 deiodinase, iodothyronine, type III
DNAH7 dynein, axonemal, heavy chain 7
DOK5 docking protein 5
DPF3 D4, zinc and double PHD fingers, family 3
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
ERO1LB ERO1-like beta (S. cerevisiae)
FBXL2 F-box and leucine-rich repeat protein 2
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H3I histone cluster 1, H3i
HIST1H4E histone cluster 1, H4e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA2 homeobox A2
HOXC5 homeobox C5
HSPA1L heat shock 70kDa protein 1-like
IL17RB interleukin 17 receptor B
IRAK4 interleukin-1 receptor-associated kinase 4
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCTD20 potassium channel tetramerization domain containing 20
KIAA1107 KIAA1107
LMTK2 lemur tyrosine kinase 2
LOC157562 uncharacterized LOC157562
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MEFV Mediterranean fever
MEGF8 multiple EGF-like-domains 8
MEIS1 Meis homeobox 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NID2 nidogen 2 (osteonidogen)
NIPAL2 NIPA-like domain containing 2
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHA9 protocadherin alpha 9
PRPH peripherin
PRR15L proline rich 15-like
PXMP4 peroxisomal membrane protein 4, 24kDa
RFPL3 ret finger protein-like 3
RGCC regulator of cell cycle
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
SAYSD1 SAYSVFN motif domain containing 1
SCARA3 scavenger receptor class A, member 3
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SMO smoothened, frizzled class receptor
SNRPN small nuclear ribonucleoprotein polypeptide N
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
SYCE1L synaptonemal complex central element protein 1-like
TAGLN3 transgelin 3
TCEAL2 transcription elongation factor A (SII)-like 2
TESPA1 thymocyte expressed, positive selection associated 1
THRAP3 thyroid hormone receptor associated protein 3
TMEM212 transmembrane protein 212
TRIM25 tripartite motif containing 25
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
USP20 ubiquitin specific peptidase 20
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZNF428 zinc finger protein 428
ZNF611 zinc finger protein 611
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862