atractyloside-4717 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the atractyloside-4717 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ABHD6 abhydrolase domain containing 6
ACVR1B activin A receptor, type IB
ADGRG2 adhesion G protein-coupled receptor G2
ANGEL2 angel homolog 2 (Drosophila)
APOM apolipoprotein M
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARNT aryl hydrocarbon receptor nuclear translocator
ARTN artemin
CALML3 calmodulin-like 3
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC121 coiled-coil domain containing 121
CCDC186 coiled-coil domain containing 186
CCKBR cholecystokinin B receptor
CDC14A cell division cycle 14A
CDC25C cell division cycle 25C
COL14A1 collagen, type XIV, alpha 1
CPQ carboxypeptidase Q
CREM cAMP responsive element modulator
DCX doublecortin
DZIP1 DAZ interacting zinc finger protein 1
EFNB3 ephrin-B3
EPHB2 EPH receptor B2
FGF12 fibroblast growth factor 12
FOXP3 forkhead box P3
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GBP2 guanylate binding protein 2, interferon-inducible
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GPR85 G protein-coupled receptor 85
GRM7 glutamate receptor, metabotropic 7
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HLF hepatic leukemia factor
HOXB2 homeobox B2
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP6 insulin-like growth factor binding protein 6
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM6A lysine (K)-specific demethylase 6A
KLF2 Kruppel-like factor 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LEFTY2 left-right determination factor 2
LGALS2 lectin, galactoside-binding, soluble, 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LMO4 LIM domain only 4
LRMP lymphoid-restricted membrane protein
MPZ myelin protein zero
NFRKB nuclear factor related to kappaB binding protein
OLFML2A olfactomedin-like 2A
OMD osteomodulin
OSBP2 oxysterol binding protein 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PCDHA6 protocadherin alpha 6
PCDHB8 protocadherin beta 8
PLD2 phospholipase D2
PLEKHS1 pleckstrin homology domain containing, family S member 1
POFUT1 protein O-fucosyltransferase 1
PPARG peroxisome proliferator-activated receptor gamma
PPP5C protein phosphatase 5, catalytic subunit
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYY peptide YY
RAB3B RAB3B, member RAS oncogene family
RAG2 recombination activating gene 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAPER S-phase cyclin A-associated protein in the ER
SCG2 secretogranin II
SCN10A sodium channel, voltage gated, type X alpha subunit
SECTM1 secreted and transmembrane 1
SEZ6L seizure related 6 homolog (mouse)-like
SH3BP2 SH3-domain binding protein 2
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSX3 synovial sarcoma, X breakpoint 3
STRN3 striatin, calmodulin binding protein 3
SYBU syntabulin (syntaxin-interacting)
SYCE1L synaptonemal complex central element protein 1-like
SYT5 synaptotagmin V
TBC1D2B TBC1 domain family, member 2B
TBX3 T-box 3
TFF2 trefoil factor 2
THSD4 thrombospondin, type I, domain containing 4
TIMP3 TIMP metallopeptidase inhibitor 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMPRSS15 transmembrane protease, serine 15
TMPRSS4 transmembrane protease, serine 4
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
VAMP4 vesicle-associated membrane protein 4
VEZT vezatin, adherens junctions transmembrane protein
VPS9D1 VPS9 domain containing 1
WDR55 WD repeat domain 55
ZFHX2 zinc finger homeobox 2
ZNF480 zinc finger protein 480

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACBD4 acyl-CoA binding domain containing 4
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
ATAD5 ATPase family, AAA domain containing 5
B9D2 B9 protein domain 2
BFSP1 beaded filament structural protein 1, filensin
C2ORF27A chromosome 2 open reading frame 27A
C5ORF45 chromosome 5 open reading frame 45
C7ORF69 chromosome 7 open reading frame 69
CAMK1 calcium/calmodulin-dependent protein kinase I
CBX7 chromobox homolog 7
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CDHR2 cadherin-related family member 2
CEL carboxyl ester lipase
CRY2 cryptochrome circadian clock 2
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DSCAM Down syndrome cell adhesion molecule
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
ETNK2 ethanolamine kinase 2
FAM184A family with sequence similarity 184, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLJ21369 uncharacterized protein FLJ21369
FLJ22184
FSTL3 follistatin-like 3 (secreted glycoprotein)
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMPR guanosine monophosphate reductase
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITPKB inositol-trisphosphate 3-kinase B
KIF13A kinesin family member 13A
KPNA5 karyopherin alpha 5 (importin alpha 6)
LHX6 LIM homeobox 6
LIN7A lin-7 homolog A (C. elegans)
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MED18 mediator complex subunit 18
MYO1F myosin IF
NEUROD4 neuronal differentiation 4
NIPAL2 NIPA-like domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPIPB3 nuclear pore complex interacting protein family, member B3
NPR3 natriuretic peptide receptor 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHA9 protocadherin alpha 9
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRB3 proline-rich protein BstNI subfamily 3
PSKH1 protein serine kinase H1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PVRL3 poliovirus receptor-related 3
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
S100A9 S100 calcium binding protein A9
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A9 solute carrier family 12, member 9
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNTA1 syntrophin, alpha 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNC syncoilin, intermediate filament protein
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEP1 telomerase-associated protein 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM212 transmembrane protein 212
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VASH2 vasohibin 2
WDR76 WD repeat domain 76
ZNF205 zinc finger protein 205
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747