| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the atractyloside-7393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CABP2 | calcium binding protein 2 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CDC25C | cell division cycle 25C |
| CDK10 | cyclin-dependent kinase 10 |
| CES1 | carboxylesterase 1 |
| CES3 | carboxylesterase 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCLK2 | doublecortin-like kinase 2 |
| DCN | decorin |
| DENND2A | DENN/MADD domain containing 2A |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DOCK9 | dedicator of cytokinesis 9 |
| DPT | dermatopontin |
| EDA | ectodysplasin A |
| ETV1 | ets variant 1 |
| ETV5 | ets variant 5 |
| EWSR1 | EWS RNA-binding protein 1 |
| FAM186A | family with sequence similarity 186, member A |
| FKBP8 | FK506 binding protein 8, 38kDa |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR1 | G protein-coupled receptor 1 |
| GUK1 | guanylate kinase 1 |
| HAUS5 | HAUS augmin-like complex, subunit 5 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HOXB5 | homeobox B5 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IL17RA | interleukin 17 receptor A |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| KITLG | KIT ligand |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MDFIC | MyoD family inhibitor domain containing |
| METRN | meteorin, glial cell differentiation regulator |
| MRPL57 | mitochondrial ribosomal protein L57 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC4 | mucin 4, cell surface associated |
| MYLK | myosin light chain kinase |
| MYOZ1 | myozenin 1 |
| NAIP | NLR family, apoptosis inhibitory protein |
| NCOA2 | nuclear receptor coactivator 2 |
| NPR3 | natriuretic peptide receptor 3 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCDHB13 | protocadherin beta 13 |
| PCM1 | pericentriolar material 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PIAS4 | protein inhibitor of activated STAT, 4 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRDM2 | PR domain containing 2, with ZNF domain |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| SAPCD1 | suppressor APC domain containing 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGSM3 | small G protein signaling modulator 3 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SREBF2 | sterol regulatory element binding transcription factor 2 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| THBS3 | thrombospondin 3 |
| TLN2 | talin 2 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| WSB1 | WD repeat and SOCS box containing 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| YTHDC1 | YTH domain containing 1 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZNF141 | zinc finger protein 141 |
| ZNF205 | zinc finger protein 205 |
| ZNF276 | zinc finger protein 276 |
| ZNF408 | zinc finger protein 408 |
| ZNF442 | zinc finger protein 442 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| AFAP1 | actin filament associated protein 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BRCA2 | breast cancer 2, early onset |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CAPN15 | calpain 15 |
| CASZ1 | castor zinc finger 1 |
| CBX7 | chromobox homolog 7 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDH7 | cadherin 7, type 2 |
| CDON | cell adhesion associated, oncogene regulated |
| CFAP44 | cilia and flagella associated protein 44 |
| CISH | cytokine inducible SH2-containing protein |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DUSP10 | dual specificity phosphatase 10 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FA2H | fatty acid 2-hydroxylase |
| FADS2 | fatty acid desaturase 2 |
| FOXC1 | forkhead box C1 |
| GAB2 | GRB2-associated binding protein 2 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HIST1H3C | histone cluster 1, H3c |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFI44L | interferon-induced protein 44-like |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IPO8 | importin 8 |
| ISL1 | ISL LIM homeobox 1 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA1107 | KIAA1107 |
| KIF16B | kinesin family member 16B |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KRT34 | keratin 34, type I |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| METTL16 | methyltransferase like 16 |
| MMP1 | matrix metallopeptidase 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| NCS1 | neuronal calcium sensor 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NUBP2 | nucleotide binding protein 2 |
| OLFML2A | olfactomedin-like 2A |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLAC8 | placenta-specific 8 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLH | polymerase (DNA directed), eta |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RARS | arginyl-tRNA synthetase |
| RBM47 | RNA binding motif protein 47 |
| SALL2 | spalt-like transcription factor 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| STAC | SH3 and cysteine rich domain |
| STIM1 | stromal interaction molecule 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM53 | transmembrane protein 53 |
| TNNI3 | troponin I type 3 (cardiac) |
| TRABD | TraB domain containing |
| TRAPPC11 | trafficking protein particle complex 11 |
| TRIM26 | tripartite motif containing 26 |
| TTC31 | tetratricopeptide repeat domain 31 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VEGFB | vascular endothelial growth factor B |
| YOD1 | YOD1 deubiquitinase |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF175 | zinc finger protein 175 |
| ZNF189 | zinc finger protein 189 |
| ZNF34 | zinc finger protein 34 |
| ZNF510 | zinc finger protein 510 |
