Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the atropine oxide-1370 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ADK | adenosine kinase |
ANKRD36 | ankyrin repeat domain 36 |
ASMTL | acetylserotonin O-methyltransferase-like |
ATF2 | activating transcription factor 2 |
ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
ATXN7 | ataxin 7 |
AZI2 | 5-azacytidine induced 2 |
C17ORF75 | chromosome 17 open reading frame 75 |
CCPG1 | cell cycle progression 1 |
CD300A | CD300a molecule |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CEP152 | centrosomal protein 152kDa |
CHD9 | chromodomain helicase DNA binding protein 9 |
CLCC1 | chloride channel CLIC-like 1 |
CTSS | cathepsin S |
DENND4A | DENN/MADD domain containing 4A |
DPYD | dihydropyrimidine dehydrogenase |
DSCR3 | Down syndrome critical region 3 |
DUS2 | dihydrouridine synthase 2 |
EID1 | EP300 interacting inhibitor of differentiation 1 |
EIF5B | eukaryotic translation initiation factor 5B |
ELF2 | E74-like factor 2 (ets domain transcription factor) |
EPB41L3 | erythrocyte membrane protein band 4.1-like 3 |
FASTK | Fas-activated serine/threonine kinase |
FLI1 | Fli-1 proto-oncogene, ETS transcription factor |
GCA | grancalcin, EF-hand calcium binding protein |
GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
GPSM2 | G-protein signaling modulator 2 |
HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
HOMER1 | homer scaffolding protein 1 |
IL1B | interleukin 1, beta |
ITM2B | integral membrane protein 2B |
KIF20B | kinesin family member 20B |
KLHL7 | kelch-like family member 7 |
KRIT1 | KRIT1, ankyrin repeat containing |
LARP4 | La ribonucleoprotein domain family, member 4 |
LIN7C | lin-7 homolog C (C. elegans) |
MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
MAGOH2P | mago-nashi homolog 2, pseudogene |
MAGOHB | mago-nashi homolog B (Drosophila) |
MAN1B1 | mannosidase, alpha, class 1B, member 1 |
MED7 | mediator complex subunit 7 |
METTL7A | methyltransferase like 7A |
MORC3 | MORC family CW-type zinc finger 3 |
MPP6 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
MSH3 | mutS homolog 3 |
NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
PAPOLA | poly(A) polymerase alpha |
PCBP2 | poly(rC) binding protein 2 |
PHACTR2 | phosphatase and actin regulator 2 |
PICALM | phosphatidylinositol binding clathrin assembly protein |
PLAGL1 | pleiomorphic adenoma gene-like 1 |
PLK4 | polo-like kinase 4 |
PNISR | PNN-interacting serine/arginine-rich protein |
POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
RAB11A | RAB11A, member RAS oncogene family |
RAD17 | RAD17 homolog (S. pombe) |
RBBP6 | retinoblastoma binding protein 6 |
RGS1 | regulator of G-protein signaling 1 |
RHEB | Ras homolog enriched in brain |
RIOK3 | RIO kinase 3 |
RPL15 | ribosomal protein L15 |
RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 |
RSF1 | remodeling and spacing factor 1 |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCAF4 | SR-related CTD-associated factor 4 |
SEC23B | Sec23 homolog B (S. cerevisiae) |
SEC24D | SEC24 family member D |
SIGLEC7 | sialic acid binding Ig-like lectin 7 |
SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
SMG5 | SMG5 nonsense mediated mRNA decay factor |
SNX11 | sorting nexin 11 |
SPN | sialophorin |
SRSF11 | serine/arginine-rich splicing factor 11 |
STK19 | serine/threonine kinase 19 |
SUB1 | SUB1 homolog (S. cerevisiae) |
TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
TANK | TRAF family member-associated NFKB activator |
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) |
TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
TMED7 | transmembrane emp24 protein transport domain containing 7 |
TSPAN31 | tetraspanin 31 |
TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
UBA2 | ubiquitin-like modifier activating enzyme 2 |
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
UBE3A | ubiquitin protein ligase E3A |
USF2 | upstream transcription factor 2, c-fos interacting |
WIZ | widely interspaced zinc finger motifs |
YIPF4 | Yip1 domain family, member 4 |
ZEB2 | zinc finger E-box binding homeobox 2 |
ZMYM2 | zinc finger, MYM-type 2 |
ZNF280D | zinc finger protein 280D |
ZNF426 | zinc finger protein 426 |
ZNF79 | zinc finger protein 79 |
Symbol | Name |
---|---|
ACOT13 | acyl-CoA thioesterase 13 |
ACOT8 | acyl-CoA thioesterase 8 |
ADAT1 | adenosine deaminase, tRNA-specific 1 |
ADTRP | androgen-dependent TFPI-regulating protein |
AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
APOD | apolipoprotein D |
ARHGAP10 | Rho GTPase activating protein 10 |
ATAT1 | alpha tubulin acetyltransferase 1 |
B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
BAHD1 | bromo adjacent homology domain containing 1 |
C8ORF60 | chromosome 8 open reading frame 60 |
CALCOCO1 | calcium binding and coiled-coil domain 1 |
CCDC176 | coiled-coil domain containing 176 |
CD151 | CD151 molecule (Raph blood group) |
CD82 | CD82 molecule |
CEP70 | centrosomal protein 70kDa |
CER1 | cerberus 1, DAN family BMP antagonist |
CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
CLDN11 | claudin 11 |
CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
CNR2 | cannabinoid receptor 2 (macrophage) |
CNTD2 | cyclin N-terminal domain containing 2 |
CNTNAP1 | contactin associated protein 1 |
CPA4 | carboxypeptidase A4 |
DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
DOK2 | docking protein 2, 56kDa |
DPF3 | D4, zinc and double PHD fingers, family 3 |
EDAR | ectodysplasin A receptor |
ERCC8 | excision repair cross-complementation group 8 |
FBXL6 | F-box and leucine-rich repeat protein 6 |
FHOD1 | formin homology 2 domain containing 1 |
FMO4 | flavin containing monooxygenase 4 |
GAA | glucosidase, alpha; acid |
GBAP1 | glucosidase, beta, acid pseudogene 1 |
GLB1L2 | galactosidase, beta 1-like 2 |
GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
GPR27 | G protein-coupled receptor 27 |
GTPBP2 | GTP binding protein 2 |
HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
IFITM3 | interferon induced transmembrane protein 3 |
IL2RB | interleukin 2 receptor, beta |
IL2RG | interleukin 2 receptor, gamma |
INO80D | INO80 complex subunit D |
ITPKC | inositol-trisphosphate 3-kinase C |
JMJD4 | jumonji domain containing 4 |
KIAA0355 | KIAA0355 |
KIF5A | kinesin family member 5A |
KLK1 | kallikrein 1 |
LMBR1L | limb development membrane protein 1-like |
MAGEF1 | melanoma antigen family F1 |
MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
MFSD11 | major facilitator superfamily domain containing 11 |
MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
NCKAP1L | NCK-associated protein 1-like |
NHEJ1 | nonhomologous end-joining factor 1 |
NUBP2 | nucleotide binding protein 2 |
NXPH3 | neurexophilin 3 |
OVGP1 | oviductal glycoprotein 1, 120kDa |
PADI1 | peptidyl arginine deiminase, type I |
PCDHGB5 | protocadherin gamma subfamily B, 5 |
PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
PDLIM2 | PDZ and LIM domain 2 (mystique) |
PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
QPRT | quinolinate phosphoribosyltransferase |
SCAMP5 | secretory carrier membrane protein 5 |
SCN1B | sodium channel, voltage gated, type I beta subunit |
SDF2L1 | stromal cell-derived factor 2-like 1 |
SH3GL1 | SH3-domain GRB2-like 1 |
SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
SLN | sarcolipin |
SNTA1 | syntrophin, alpha 1 |
SREBF1 | sterol regulatory element binding transcription factor 1 |
STAC | SH3 and cysteine rich domain |
STARD3 | StAR-related lipid transfer (START) domain containing 3 |
SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
TAC3 | tachykinin 3 |
TGFB3 | transforming growth factor, beta 3 |
TMPRSS6 | transmembrane protease, serine 6 |
TRIM26 | tripartite motif containing 26 |
TRIM66 | tripartite motif containing 66 |
TRMT12 | tRNA methyltransferase 12 homolog (S. cerevisiae) |
TSPAN32 | tetraspanin 32 |
TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
TXLNA | taxilin alpha |
UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
UNC45A | unc-45 homolog A (C. elegans) |
UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) |
WFS1 | Wolfram syndrome 1 (wolframin) |
YIPF1 | Yip1 domain family, member 1 |
ZBED1 | zinc finger, BED-type containing 1 |
ZNF408 | zinc finger protein 408 |
ZNHIT2 | zinc finger, HIT-type containing 2 |