atropine oxide-2054 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the atropine oxide-2054 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABHD17B abhydrolase domain containing 17B
ABI3BP ABI family, member 3 (NESH) binding protein
ADH6 alcohol dehydrogenase 6 (class V)
ALPK1 alpha-kinase 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARNT aryl hydrocarbon receptor nuclear translocator
BGLAP bone gamma-carboxyglutamate (gla) protein
BTG2 BTG family, member 2
C10ORF10 chromosome 10 open reading frame 10
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLDN17 claudin 17
CNOT1 CCR4-NOT transcription complex, subunit 1
CSF1 colony stimulating factor 1 (macrophage)
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DOHH deoxyhypusine hydroxylase/monooxygenase
DUS2 dihydrouridine synthase 2
EDRF1 erythroid differentiation regulatory factor 1
EFNA3 ephrin-A3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXO21 F-box protein 21
FKBP8 FK506 binding protein 8, 38kDa
GFER growth factor, augmenter of liver regeneration
GLB1L2 galactosidase, beta 1-like 2
GPR3 G protein-coupled receptor 3
GSK3A glycogen synthase kinase 3 alpha
HAPLN1 hyaluronan and proteoglycan link protein 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOOK1 hook microtubule-tethering protein 1
HOXB5 homeobox B5
IFI6 interferon, alpha-inducible protein 6
IGF1R insulin-like growth factor 1 receptor
IL15 interleukin 15
KDM4C lysine (K)-specific demethylase 4C
KIDINS220 kinase D-interacting substrate, 220kDa
KLF3 Kruppel-like factor 3 (basic)
KYNU kynureninase
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP6 low density lipoprotein receptor-related protein 6
MIIP migration and invasion inhibitory protein
MYRF myelin regulatory factor
NCKIPSD NCK interacting protein with SH3 domain
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGDHL oxoglutarate dehydrogenase-like
PCDH9 protocadherin 9
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHC1 polyhomeotic homolog 1 (Drosophila)
PLXNB3 plexin B3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PTGES prostaglandin E synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASAL2 RAS protein activator like 2
REEP1 receptor accessory protein 1
RIF1 replication timing regulatory factor 1
RWDD2A RWD domain containing 2A
S1PR1 sphingosine-1-phosphate receptor 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC17A2 solute carrier family 17, member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPATA5L1 spermatogenesis associated 5-like 1
SPHK2 sphingosine kinase 2
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
SUGP1 SURP and G patch domain containing 1
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D4 TBC1 domain family, member 4
TEX261 testis expressed 261
THBS3 thrombospondin 3
TJP3 tight junction protein 3
TLN2 talin 2
TNS2 tensin 2
TOP3A topoisomerase (DNA) III alpha
TOR4A torsin family 4, member A
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN12 tetraspanin 12
TTC38 tetratricopeptide repeat domain 38
TXLNG taxilin gamma
USP46 ubiquitin specific peptidase 46
USP48 ubiquitin specific peptidase 48
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WDFY3 WD repeat and FYVE domain containing 3
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZFP30 ZFP30 zinc finger protein
ZMYM6 zinc finger, MYM-type 6
ZNF137P zinc finger protein 137, pseudogene
ZNF510 zinc finger protein 510
ZNF710 zinc finger protein 710
ZNF93 zinc finger protein 93
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ACOX2 acyl-CoA oxidase 2, branched chain
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADCY6 adenylate cyclase 6
AGO3 argonaute RISC catalytic component 3
AHDC1 AT hook, DNA binding motif, containing 1
AKIP1 A kinase (PRKA) interacting protein 1
AKTIP AKT interacting protein
ANG angiogenin, ribonuclease, RNase A family, 5
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ARRB2 arrestin, beta 2
ATOX1 antioxidant 1 copper chaperone
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
BCAS3 breast carcinoma amplified sequence 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDIP1 cell death-inducing p53 target 1
CHPF chondroitin polymerizing factor
CLCN5 chloride channel, voltage-sensitive 5
CTAGE9 CTAGE family, member 9
CTNNBL1 catenin, beta like 1
CUEDC1 CUE domain containing 1
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DNAL4 dynein, axonemal, light chain 4
DTWD1 DTW domain containing 1
ECI1 enoyl-CoA delta isomerase 1
EDC3 enhancer of mRNA decapping 3
EGF epidermal growth factor
ERF Ets2 repressor factor
EVPL envoplakin
FICD FIC domain containing
GATAD2A GATA zinc finger domain containing 2A
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPALPP1 GPALPP motifs containing 1
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
HOXB13 homeobox B13
ICE2 interactor of little elongation complex ELL subunit 2
IL32 interleukin 32
KDM5C lysine (K)-specific demethylase 5C
KIAA0355 KIAA0355
LAGE3 L antigen family, member 3
LYPLA2P1 lysophospholipase II pseudogene 1
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MFGE8 milk fat globule-EGF factor 8 protein
NCS1 neuronal calcium sensor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME3 NME/NM23 nucleoside diphosphate kinase 3
NOL12 nucleolar protein 12
NPDC1 neural proliferation, differentiation and control, 1
NR1D2 nuclear receptor subfamily 1, group D, member 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAQR4 progestin and adipoQ receptor family member IV
PAQR6 progestin and adipoQ receptor family member VI
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PFDN1 prefoldin subunit 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PMF1 polyamine-modulated factor 1
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
QTRT1 queuine tRNA-ribosyltransferase 1
RAB33B RAB33B, member RAS oncogene family
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RNF170 ring finger protein 170
RNF25 ring finger protein 25
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCYL2 SCY1-like 2 (S. cerevisiae)
SIX1 SIX homeobox 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D12 TBC1 domain family, member 12
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THOC1 THO complex 1
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMCO3 transmembrane and coiled-coil domains 3
TMEM260 transmembrane protein 260
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNNI3 troponin I type 3 (cardiac)
TRAPPC6A trafficking protein particle complex 6A
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
UBE2O ubiquitin-conjugating enzyme E2O
UBQLN4 ubiquilin 4
ULBP2 UL16 binding protein 2
UNC119 unc-119 homolog (C. elegans)
UNKL unkempt family zinc finger-like
WDR91 WD repeat domain 91
WWC2 WW and C2 domain containing 2
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF394 zinc finger protein 394