atropine-1768 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the atropine-1768 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ARHGAP35 Rho GTPase activating protein 35
ARHGAP4 Rho GTPase activating protein 4
ARL6IP4 ADP-ribosylation factor-like 6 interacting protein 4
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARR3 arrestin 3, retinal (X-arrestin)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BICD1 bicaudal D homolog 1 (Drosophila)
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BTG2 BTG family, member 2
CAPN10 calpain 10
CBFB core-binding factor, beta subunit
CDC123 cell division cycle 123
CDV3 CDV3 homolog (mouse)
CREM cAMP responsive element modulator
CST3 cystatin C
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTRL chymotrypsin-like
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCAF15 DDB1 and CUL4 associated factor 15
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
ELMO2 engulfment and cell motility 2
EXOSC4 exosome component 4
FXR1 fragile X mental retardation, autosomal homolog 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GBAP1 glucosidase, beta, acid pseudogene 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GNS glucosamine (N-acetyl)-6-sulfatase
GSTZ1 glutathione S-transferase zeta 1
HDAC5 histone deacetylase 5
HFE hemochromatosis
HIST1H2AM histone cluster 1, H2am
HMOX2 heme oxygenase 2
HNRNPR heterogeneous nuclear ribonucleoprotein R
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOXB5 homeobox B5
HP1BP3 heterochromatin protein 1, binding protein 3
INTS5 integrator complex subunit 5
IP6K2 inositol hexakisphosphate kinase 2
IPO8 importin 8
IRF4 interferon regulatory factor 4
ITGA7 integrin, alpha 7
KIF3C kinesin family member 3C
KMT2A lysine (K)-specific methyltransferase 2A
KRT17 keratin 17, type I
KYNU kynureninase
LAD1 ladinin 1
LAT2 linker for activation of T cells family, member 2
LRP3 low density lipoprotein receptor-related protein 3
LSM12 LSM12 homolog (S. cerevisiae)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP4 microtubule-associated protein 4
MCL1 myeloid cell leukemia 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MED21 mediator complex subunit 21
MOXD1 monooxygenase, DBH-like 1
MTERF4 mitochondrial transcription termination factor 4
NOS1 nitric oxide synthase 1 (neuronal)
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PCOLCE2 procollagen C-endopeptidase enhancer 2
PFDN6 prefoldin subunit 6
PIGR polymeric immunoglobulin receptor
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNMA3 paraneoplastic Ma antigen 3
PPIEL peptidylprolyl isomerase E-like pseudogene
PRELP proline/arginine-rich end leucine-rich repeat protein
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5C RAB5C, member RAS oncogene family
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF141 ring finger protein 141
SATB1 SATB homeobox 1
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SPN sialophorin
STK19 serine/threonine kinase 19
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TEX261 testis expressed 261
TGM5 transglutaminase 5
TMCO6 transmembrane and coiled-coil domains 6
TOX4 TOX high mobility group box family member 4
TRIP11 thyroid hormone receptor interactor 11
TRMT61A tRNA methyltransferase 61A
TSTA3 tissue specific transplantation antigen P35B
USB1 U6 snRNA biogenesis 1
VAC14 Vac14 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YLPM1 YLP motif containing 1
ZMAT5 zinc finger, matrin-type 5
ZNF142 zinc finger protein 142
ZNF419 zinc finger protein 419
ZNF43 zinc finger protein 43

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACTL6A actin-like 6A
ADCY7 adenylate cyclase 7
AGO3 argonaute RISC catalytic component 3
AHR aryl hydrocarbon receptor
ANXA5 annexin A5
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ASB8 ankyrin repeat and SOCS box containing 8
ATG9A autophagy related 9A
C5ORF28 chromosome 5 open reading frame 28
CD69 CD69 molecule
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CFL1 cofilin 1 (non-muscle)
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
COPS5 COP9 signalosome subunit 5
CS citrate synthase
CSK c-src tyrosine kinase
CTSH cathepsin H
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4 DBF4 zinc finger
DENND4A DENN/MADD domain containing 4A
DMXL1 Dmx-like 1
DSN1 DSN1, MIS12 kinetochore complex component
ERBB2IP erbb2 interacting protein
F3 coagulation factor III (thromboplastin, tissue factor)
FAM3C family with sequence similarity 3, member C
FBXO34 F-box protein 34
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPR183 G protein-coupled receptor 183
GUSBP3 glucuronidase, beta pseudogene 3
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCTD3 potassium channel tetramerization domain containing 3
LARS leucyl-tRNA synthetase
LIMA1 LIM domain and actin binding 1
LINC00339 long intergenic non-protein coding RNA 339
LRP5L low density lipoprotein receptor-related protein 5-like
LXN latexin
MAGEF1 melanoma antigen family F1
MOCS2 molybdenum cofactor synthesis 2
MRPL33 mitochondrial ribosomal protein L33
MTMR6 myotubularin related protein 6
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NEMF nuclear export mediator factor
NUCB2 nucleobindin 2
OGFRL1 opioid growth factor receptor-like 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRPF38B pre-mRNA processing factor 38B
PXMP4 peroxisomal membrane protein 4, 24kDa
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RBL1 retinoblastoma-like 1
RBM47 RNA binding motif protein 47
RBM4B RNA binding motif protein 4B
RGS13 regulator of G-protein signaling 13
RINT1 RAD50 interactor 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
SECISBP2 SECIS binding protein 2
SEH1L SEH1-like (S. cerevisiae)
SKA1 spindle and kinetochore associated complex subunit 1
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLMO2 slowmo homolog 2 (Drosophila)
SMURF2 SMAD specific E3 ubiquitin protein ligase 2
SSFA2 sperm specific antigen 2
STARD8 StAR-related lipid transfer (START) domain containing 8
STAU2 staufen double-stranded RNA binding protein 2
STIL SCL/TAL1 interrupting locus
STK26 serine/threonine protein kinase 26
STXBP3 syntaxin binding protein 3
SUOX sulfite oxidase
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TCTN2 tectonic family member 2
TMA7 translation machinery associated 7 homolog (S. cerevisiae)
TMEM53 transmembrane protein 53
TNRC6B trinucleotide repeat containing 6B
TOM1L1 target of myb1 (chicken)-like 1
TRHDE thyrotropin-releasing hormone degrading enzyme
TTF2 transcription termination factor, RNA polymerase II
UBA5 ubiquitin-like modifier activating enzyme 5
USP32 ubiquitin specific peptidase 32
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
WASF1 WAS protein family, member 1
WDR11 WD repeat domain 11
WDR47 WD repeat domain 47
WDR82 WD repeat domain 82
XAF1 XIAP associated factor 1
XPC xeroderma pigmentosum, complementation group C
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
YEATS2 YEATS domain containing 2
YEATS4 YEATS domain containing 4
ZEB2 zinc finger E-box binding homeobox 2
ZNF273 zinc finger protein 273
ZNF426 zinc finger protein 426
ZNF432 zinc finger protein 432
ZNF665 zinc finger protein 665
ZZZ3 zinc finger, ZZ-type containing 3