atropine-2761 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the atropine-2761 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
APOC1 apolipoprotein C-I
ARHGAP26 Rho GTPase activating protein 26
ARMC4 armadillo repeat containing 4
ARR3 arrestin 3, retinal (X-arrestin)
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BLVRA biliverdin reductase A
C1ORF54 chromosome 1 open reading frame 54
CA4 carbonic anhydrase IV
CADM4 cell adhesion molecule 4
CCDC81 coiled-coil domain containing 81
CD6 CD6 molecule
CEP164 centrosomal protein 164kDa
CES3 carboxylesterase 3
COL11A2 collagen, type XI, alpha 2
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
COL5A2 collagen, type V, alpha 2
COPE coatomer protein complex, subunit epsilon
CRH corticotropin releasing hormone
DGCR8 DGCR8 microprocessor complex subunit
DMPK dystrophia myotonica-protein kinase
ELOVL2 ELOVL fatty acid elongase 2
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ETV1 ets variant 1
FADS2 fatty acid desaturase 2
FSTL1 follistatin-like 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLS glutaminase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPER1 G protein-coupled estrogen receptor 1
GRB7 growth factor receptor-bound protein 7
GRM1 glutamate receptor, metabotropic 1
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HDAC5 histone deacetylase 5
HIST1H2AJ histone cluster 1, H2aj
HIST1H3E histone cluster 1, H3e
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQSEC2 IQ motif and Sec7 domain 2
KIF1C kinesin family member 1C
KREMEN2 kringle containing transmembrane protein 2
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC2 laminin, gamma 2
LAMP3 lysosomal-associated membrane protein 3
LRP2 low density lipoprotein receptor-related protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MED31 mediator complex subunit 31
MMP3 matrix metallopeptidase 3
MTAP methylthioadenosine phosphorylase
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NME5 NME/NM23 family member 5
NOL10 nucleolar protein 10
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
OPTN optineurin
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCBP3 poly(rC) binding protein 3
PCDHA5 protocadherin alpha 5
PIDD1 p53-induced death domain protein 1
PLLP plasmolipin
PRDM2 PR domain containing 2, with ZNF domain
PRF1 perforin 1 (pore forming protein)
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PVR poliovirus receptor
RETN resistin
RIMS3 regulating synaptic membrane exocytosis 3
RNF17 ring finger protein 17
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SCHIP1 schwannomin interacting protein 1
SFTPB surfactant protein B
SH2D3A SH2 domain containing 3A
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT5 sirtuin 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
STMN1 stathmin 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBL1Y transducin (beta)-like 1, Y-linked
TPM3 tropomyosin 3
TRIM36 tripartite motif containing 36
TTPA tocopherol (alpha) transfer protein
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAV2 vav 2 guanine nucleotide exchange factor
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
YIPF2 Yip1 domain family, member 2
ZBED4 zinc finger, BED-type containing 4
ZBTB7A zinc finger and BTB domain containing 7A
ZCCHC24 zinc finger, CCHC domain containing 24
ZER1 zyg-11 related, cell cycle regulator
ZNF286A zinc finger protein 286A
ZNF589 zinc finger protein 589
ZNF646 zinc finger protein 646
ZNF804A zinc finger protein 804A

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ALS2CL ALS2 C-terminal like
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BAK1 BCL2-antagonist/killer 1
BCAS4 breast carcinoma amplified sequence 4
BCL9 B-cell CLL/lymphoma 9
BCOR BCL6 corepressor
BFSP1 beaded filament structural protein 1, filensin
C4ORF29 chromosome 4 open reading frame 29
CAPG capping protein (actin filament), gelsolin-like
CAPRIN2 caprin family member 2
CBX7 chromobox homolog 7
CCDC92 coiled-coil domain containing 92
CCNE1 cyclin E1
CHKB choline kinase beta
CISH cytokine inducible SH2-containing protein
CPTP ceramide-1-phosphate transfer protein
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DNALI1 dynein, axonemal, light intermediate chain 1
DOCK1 dedicator of cytokinesis 1
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EDC4 enhancer of mRNA decapping 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERF Ets2 repressor factor
F3 coagulation factor III (thromboplastin, tissue factor)
FAM160B2 family with sequence similarity 160, member B2
FAM188A family with sequence similarity 188, member A
FANCE Fanconi anemia, complementation group E
FBXO31 F-box protein 31
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGD1 FYVE, RhoGEF and PH domain containing 1
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLB1L2 galactosidase, beta 1-like 2
GPATCH3 G patch domain containing 3
GPR87 G protein-coupled receptor 87
GSTCD glutathione S-transferase, C-terminal domain containing
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
HTRA1 HtrA serine peptidase 1
KLF3 Kruppel-like factor 3 (basic)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPKBP1 mitogen-activated protein kinase binding protein 1
MITF microphthalmia-associated transcription factor
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCALD neurocalcin delta
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPFFR1 neuropeptide FF receptor 1
NPY5R neuropeptide Y receptor Y5
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ONECUT2 one cut homeobox 2
PACS1 phosphofurin acidic cluster sorting protein 1
PANK4 pantothenate kinase 4
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHA9 protocadherin alpha 9
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAI14 retinoic acid induced 14
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFT2D2 SFT2 domain containing 2
SLC12A8 solute carrier family 12, member 8
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC41A3 solute carrier family 41, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
STARD13 StAR-related lipid transfer (START) domain containing 13
STX1A syntaxin 1A (brain)
SYCP2 synaptonemal complex protein 2
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TPCN1 two pore segment channel 1
TTC23 tetratricopeptide repeat domain 23
USP6NL USP6 N-terminal like
ZBTB44 zinc finger and BTB domain containing 44
ZBTB48 zinc finger and BTB domain containing 48
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF16 zinc finger protein 16
ZNF211 zinc finger protein 211
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF639 zinc finger protein 639
ZNF767P zinc finger family member 767, pseudogene
ZSCAN26 zinc finger and SCAN domain containing 26