| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the atropine-5865 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ACSM3 | acyl-CoA synthetase medium-chain family member 3 |
| ART1 | ADP-ribosyltransferase 1 |
| ARTN | artemin |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| C7ORF26 | chromosome 7 open reading frame 26 |
| C8A | complement component 8, alpha polypeptide |
| CATR1 | CATR tumorigenicity conversion 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNT2 | cyclin T2 |
| CCPG1 | cell cycle progression 1 |
| CDC25C | cell division cycle 25C |
| CENPO | centromere protein O |
| CEP162 | centrosomal protein 162kDa |
| COL14A1 | collagen, type XIV, alpha 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DBF4B | DBF4 zinc finger B |
| DCTN2 | dynactin 2 (p50) |
| DIAPH2 | diaphanous-related formin 2 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOK5 | docking protein 5 |
| DPYS | dihydropyrimidinase |
| DTNA | dystrobrevin, alpha |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ESR1 | estrogen receptor 1 |
| F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
| FANCA | Fanconi anemia, complementation group A |
| FBLN1 | fibulin 1 |
| FBXO40 | F-box protein 40 |
| FGB | fibrinogen beta chain |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FOXI1 | forkhead box I1 |
| FRMD4B | FERM domain containing 4B |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GNRHR | gonadotropin-releasing hormone receptor |
| GPC4 | glypican 4 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GSTA3 | glutathione S-transferase alpha 3 |
| GTF2I | general transcription factor IIi |
| H6PD | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| HDAC5 | histone deacetylase 5 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGHA1 | immunoglobulin heavy constant alpha 1 |
| IGHM | immunoglobulin heavy constant mu |
| IL1R2 | interleukin 1 receptor, type II |
| IL33 | interleukin 33 |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNH6 | potassium channel, voltage gated eag related subfamily H, member 6 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| LAMA2 | laminin, alpha 2 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC1 | leucine rich repeat containing 1 |
| MED18 | mediator complex subunit 18 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| MT1M | metallothionein 1M |
| NDUFAF5 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 5 |
| NME5 | NME/NM23 family member 5 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PAX8 | paired box 8 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PITX1 | paired-like homeodomain 1 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RANBP1 | RAN binding protein 1 |
| RARG | retinoic acid receptor, gamma |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RECQL5 | RecQ protein-like 5 |
| REEP1 | receptor accessory protein 1 |
| RUNX1 | runt-related transcription factor 1 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNTG1 | syntrophin, gamma 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STX6 | syntaxin 6 |
| TCF4 | transcription factor 4 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM19 | transmembrane protein 19 |
| VPREB1 | pre-B lymphocyte 1 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| XAF1 | XIAP associated factor 1 |
| ZNF440 | zinc finger protein 440 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACKR3 | atypical chemokine receptor 3 |
| AEN | apoptosis enhancing nuclease |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| APOLD1 | apolipoprotein L domain containing 1 |
| BAK1 | BCL2-antagonist/killer 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CAPN5 | calpain 5 |
| CASD1 | CAS1 domain containing 1 |
| CCNA1 | cyclin A1 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CDH7 | cadherin 7, type 2 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHCHD7 | coiled-coil-helix-coiled-coil-helix domain containing 7 |
| CHEK2 | checkpoint kinase 2 |
| CHMP6 | charged multivesicular body protein 6 |
| CHMP7 | charged multivesicular body protein 7 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLSPN | claspin |
| CRYBA2 | crystallin, beta A2 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLL3 | delta-like 3 (Drosophila) |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM50B | family with sequence similarity 50, member B |
| FBRS | fibrosin |
| FOXC1 | forkhead box C1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GATA6 | GATA binding protein 6 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLX | H2.0-like homeobox |
| HOXC10 | homeobox C10 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| IQCE | IQ motif containing E |
| LAMA5 | laminin, alpha 5 |
| LHX6 | LIM homeobox 6 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MEIS1 | Meis homeobox 1 |
| MVP | major vault protein |
| NECAP1 | NECAP endocytosis associated 1 |
| NLK | nemo-like kinase |
| NOC2L | nucleolar complex associated 2 homolog (S. cerevisiae) |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| PALMD | palmdelphin |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHGDH | phosphoglycerate dehydrogenase |
| PORCN | porcupine homolog (Drosophila) |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF122 | ring finger protein 122 |
| RPL10L | ribosomal protein L10-like |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPATA7 | spermatogenesis associated 7 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBL3 | transducin (beta)-like 3 |
| TMCC2 | transmembrane and coiled-coil domain family 2 |
| TMEM242 | transmembrane protein 242 |
| TOLLIP | toll interacting protein |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3D | tubulin, alpha 3d |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR18 | WD repeat domain 18 |
| WDR76 | WD repeat domain 76 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZNF217 | zinc finger protein 217 |
| ZNF34 | zinc finger protein 34 |