atropine-5865 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the atropine-5865 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AASS aminoadipate-semialdehyde synthase
ACSM3 acyl-CoA synthetase medium-chain family member 3
ART1 ADP-ribosyltransferase 1
ARTN artemin
ATXN8OS ATXN8 opposite strand (non-protein coding)
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF53 chromosome 17 open reading frame 53
C1ORF61 chromosome 1 open reading frame 61
C7ORF26 chromosome 7 open reading frame 26
C8A complement component 8, alpha polypeptide
CATR1 CATR tumorigenicity conversion 1
CCDC85C coiled-coil domain containing 85C
CCNT2 cyclin T2
CCPG1 cell cycle progression 1
CDC25C cell division cycle 25C
CENPO centromere protein O
CEP162 centrosomal protein 162kDa
COL14A1 collagen, type XIV, alpha 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CSF1R colony stimulating factor 1 receptor
CSHL1 chorionic somatomammotropin hormone-like 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBF4B DBF4 zinc finger B
DCTN2 dynactin 2 (p50)
DIAPH2 diaphanous-related formin 2
DNAL4 dynein, axonemal, light chain 4
DOK5 docking protein 5
DPYS dihydropyrimidinase
DTNA dystrobrevin, alpha
DZIP1 DAZ interacting zinc finger protein 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ESR1 estrogen receptor 1
F2RL2 coagulation factor II (thrombin) receptor-like 2
FANCA Fanconi anemia, complementation group A
FBLN1 fibulin 1
FBXO40 F-box protein 40
FGB fibrinogen beta chain
FLT3LG fms-related tyrosine kinase 3 ligand
FOXI1 forkhead box I1
FRMD4B FERM domain containing 4B
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNRHR gonadotropin-releasing hormone receptor
GPC4 glypican 4
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSTA3 glutathione S-transferase alpha 3
GTF2I general transcription factor IIi
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HDAC5 histone deacetylase 5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
IL1R2 interleukin 1 receptor, type II
IL33 interleukin 33
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KCNIP1 Kv channel interacting protein 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LAMA2 laminin, alpha 2
LPAR4 lysophosphatidic acid receptor 4
LRRC1 leucine rich repeat containing 1
MED18 mediator complex subunit 18
MSL3 male-specific lethal 3 homolog (Drosophila)
MT1M metallothionein 1M
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NME5 NME/NM23 family member 5
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PARP3 poly (ADP-ribose) polymerase family, member 3
PAX8 paired box 8
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC3 polyhomeotic homolog 3 (Drosophila)
PITX1 paired-like homeodomain 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
RANBP1 RAN binding protein 1
RARG retinoic acid receptor, gamma
RBMS2 RNA binding motif, single stranded interacting protein 2
RECQL5 RecQ protein-like 5
REEP1 receptor accessory protein 1
RUNX1 runt-related transcription factor 1
SERGEF secretion regulating guanine nucleotide exchange factor
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNTG1 syntrophin, gamma 1
SPINK5 serine peptidase inhibitor, Kazal type 5
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STX6 syntaxin 6
TCF4 transcription factor 4
TLE4 transducin-like enhancer of split 4
TMEM19 transmembrane protein 19
VPREB1 pre-B lymphocyte 1
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
XAF1 XIAP associated factor 1
ZNF440 zinc finger protein 440
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACKR3 atypical chemokine receptor 3
AEN apoptosis enhancing nuclease
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APOLD1 apolipoprotein L domain containing 1
BAK1 BCL2-antagonist/killer 1
C19ORF40 chromosome 19 open reading frame 40
C1ORF159 chromosome 1 open reading frame 159
C5ORF45 chromosome 5 open reading frame 45
CAPN15 calpain 15
CAPN5 calpain 5
CASD1 CAS1 domain containing 1
CCNA1 cyclin A1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CFAP44 cilia and flagella associated protein 44
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHEK2 checkpoint kinase 2
CHMP6 charged multivesicular body protein 6
CHMP7 charged multivesicular body protein 7
CLCF1 cardiotrophin-like cytokine factor 1
CLSPN claspin
CRYBA2 crystallin, beta A2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DLL3 delta-like 3 (Drosophila)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EAF2 ELL associated factor 2
EFNA3 ephrin-A3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM50B family with sequence similarity 50, member B
FBRS fibrosin
FOXC1 forkhead box C1
GAMT guanidinoacetate N-methyltransferase
GATA6 GATA binding protein 6
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNPDA1 glucosamine-6-phosphate deaminase 1
HAMP hepcidin antimicrobial peptide
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HLX H2.0-like homeobox
HOXC10 homeobox C10
INPPL1 inositol polyphosphate phosphatase-like 1
IQCE IQ motif containing E
LAMA5 laminin, alpha 5
LHX6 LIM homeobox 6
LIMS2 LIM and senescent cell antigen-like domains 2
MAPK12 mitogen-activated protein kinase 12
MEIS1 Meis homeobox 1
MVP major vault protein
NECAP1 NECAP endocytosis associated 1
NLK nemo-like kinase
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NR1H2 nuclear receptor subfamily 1, group H, member 2
PALMD palmdelphin
PDLIM2 PDZ and LIM domain 2 (mystique)
PECR peroxisomal trans-2-enoyl-CoA reductase
PHACTR4 phosphatase and actin regulator 4
PHGDH phosphoglycerate dehydrogenase
PORCN porcupine homolog (Drosophila)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB1 Rho-related BTB domain containing 1
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SND1-IT1 SND1 intronic transcript 1
SOBP sine oculis binding protein homolog (Drosophila)
SPATA7 spermatogenesis associated 7
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUN2 Sad1 and UNC84 domain containing 2
TBL3 transducin (beta)-like 3
TMCC2 transmembrane and coiled-coil domain family 2
TMEM242 transmembrane protein 242
TOLLIP toll interacting protein
TRAPPC6A trafficking protein particle complex 6A
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC23 tetratricopeptide repeat domain 23
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR18 WD repeat domain 18
WDR76 WD repeat domain 76
ZBTB10 zinc finger and BTB domain containing 10
ZNF217 zinc finger protein 217
ZNF34 zinc finger protein 34