atropine-7219 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the atropine-7219 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ANGEL2 angel homolog 2 (Drosophila)
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARL4C ADP-ribosylation factor-like 4C
ASIC1 acid sensing (proton gated) ion channel 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF79 chromosome 14 open reading frame 79
CCDC121 coiled-coil domain containing 121
CD300A CD300a molecule
CD53 CD53 molecule
CFAP45 cilia and flagella associated protein 45
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC4E C-type lectin domain family 4, member E
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DAGLA diacylglycerol lipase, alpha
DBF4B DBF4 zinc finger B
DHODH dihydroorotate dehydrogenase (quinone)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOCK5 dedicator of cytokinesis 5
EHBP1L1 EH domain binding protein 1-like 1
FCMR Fc fragment of IgM receptor
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
FYB FYN binding protein
GDAP1 ganglioside induced differentiation associated protein 1
GFER growth factor, augmenter of liver regeneration
GPR183 G protein-coupled receptor 183
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HCAR3 hydroxycarboxylic acid receptor 3
HFE hemochromatosis
HIST1H3A histone cluster 1, H3a
HSPG2 heparan sulfate proteoglycan 2
IFT122 intraflagellar transport 122
IGFBP5 insulin-like growth factor binding protein 5
IL22 interleukin 22
IRS2 insulin receptor substrate 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KITLG KIT ligand
LMAN1 lectin, mannose-binding, 1
LOC57399 uncharacterized gastric protein ZA52P
LOC647070 uncharacterized LOC647070
LTBP4 latent transforming growth factor beta binding protein 4
MCAM melanoma cell adhesion molecule
MINK1 misshapen-like kinase 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCOR2 nuclear receptor corepressor 2
NIPAL2 NIPA-like domain containing 2
NTNG1 netrin G1
NUP50 nucleoporin 50kDa
OLAH oleoyl-ACP hydrolase
ORAI2 ORAI calcium release-activated calcium modulator 2
PCDHA6 protocadherin alpha 6
PHF20L1 PHD finger protein 20-like 1
POU6F2 POU class 6 homeobox 2
PRKCI protein kinase C, iota
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PROS1 protein S (alpha)
RAPSN receptor-associated protein of the synapse
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBMY2FP RNA binding motif protein, Y-linked, family 2, member F pseudogene
RCAN3 RCAN family member 3
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
RPL7 ribosomal protein L7
RSU1 Ras suppressor protein 1
SAMD4A sterile alpha motif domain containing 4A
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC25A30 solute carrier family 25, member 30
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SMC1A structural maintenance of chromosomes 1A
SOS2 son of sevenless homolog 2 (Drosophila)
SOX30 SRY (sex determining region Y)-box 30
SSPN sarcospan
STK3 serine/threonine kinase 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYT5 synaptotagmin V
TACR1 tachykinin receptor 1
TAOK2 TAO kinase 2
TMEM120B transmembrane protein 120B
TMEM63A transmembrane protein 63A
TMLHE trimethyllysine hydroxylase, epsilon
TMOD1 tropomodulin 1
TONSL tonsoku-like, DNA repair protein
WDTC1 WD and tetratricopeptide repeats 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF428 zinc finger protein 428
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADCY6 adenylate cyclase 6
AGBL5 ATP/GTP binding protein-like 5
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATAD3A ATPase family, AAA domain containing 3A
AXIN1 axin 1
BMP4 bone morphogenetic protein 4
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
C2ORF44 chromosome 2 open reading frame 44
C4ORF29 chromosome 4 open reading frame 29
C5ORF45 chromosome 5 open reading frame 45
CAMTA2 calmodulin binding transcription activator 2
CAPG capping protein (actin filament), gelsolin-like
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CIC capicua transcriptional repressor
CORO2A coronin, actin binding protein, 2A
CRLF1 cytokine receptor-like factor 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAL4 dynein, axonemal, light chain 4
FAM131A family with sequence similarity 131, member A
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
FZD2 frizzled class receptor 2
GATA6 GATA binding protein 6
GLS2 glutaminase 2 (liver, mitochondrial)
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPRASP1 G protein-coupled receptor associated sorting protein 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HPSE heparanase
IREB2 iron-responsive element binding protein 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KAT2A K(lysine) acetyltransferase 2A
KDM5C lysine (K)-specific demethylase 5C
LHX6 LIM homeobox 6
LMCD1 LIM and cysteine-rich domains 1
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC14 leucine rich repeat containing 14
LRRC8E leucine rich repeat containing 8 family, member E
LY6D lymphocyte antigen 6 complex, locus D
LYPD1 LY6/PLAUR domain containing 1
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL2B methyltransferase like 2B
MFSD11 major facilitator superfamily domain containing 11
MICB MHC class I polypeptide-related sequence B
MYO1E myosin IE
NRSN2 neurensin 2
OTUD3 OTU deubiquitinase 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PELI1 pellino E3 ubiquitin protein ligase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PTBP2 polypyrimidine tract binding protein 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBL1 retinoblastoma-like 1
RECQL4 RecQ protein-like 4
REEP4 receptor accessory protein 4
RNF170 ring finger protein 170
RPS17P5 ribosomal protein S17 pseudogene 5
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
RUFY2 RUN and FYVE domain containing 2
SCAI suppressor of cancer cell invasion
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SECISBP2 SECIS binding protein 2
SFT2D2 SFT2 domain containing 2
SH2B3 SH2B adaptor protein 3
SIK1 salt-inducible kinase 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
TEP1 telomerase-associated protein 1
TESK1 testis-specific kinase 1
TMEM127 transmembrane protein 127
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNRC6B trinucleotide repeat containing 6B
TRAIP TRAF interacting protein
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRNAU1AP tRNA selenocysteine 1 associated protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP20 ubiquitin specific peptidase 20
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZNF219 zinc finger protein 219
ZNF226 zinc finger protein 226