attenuation Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

201 genes co-occuring with the biological term attenuation in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACRBP acrosin binding protein
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AGR2 anterior gradient 2
AGTR1 angiotensin II receptor, type 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANTXR1 anthrax toxin receptor 1
AP2M1 adaptor-related protein complex 2, mu 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARG1 arginase 1
ARHGAP21 Rho GTPase activating protein 21
ARRB2 arrestin, beta 2
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
C4BPA complement component 4 binding protein, alpha
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CAT catalase
CCND1 cyclin D1
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CD209 CD209 molecule
CDC6 cell division cycle 6
CDH13 cadherin 13
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CES1 carboxylesterase 1
CFH complement factor H
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHUK conserved helix-loop-helix ubiquitous kinase
CNR2 cannabinoid receptor 2 (macrophage)
CPB2 carboxypeptidase B2 (plasma)
CREB1 cAMP responsive element binding protein 1
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTBP1 C-terminal binding protein 1
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DPP4 dipeptidyl-peptidase 4
DUSP8 dual specificity phosphatase 8
DUSP9 dual specificity phosphatase 9
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENO2 enolase 2 (gamma, neuronal)
ERF Ets2 repressor factor
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
ETV1 ets variant 1
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR1 fibroblast growth factor receptor 1
FKBP1A FK506 binding protein 1A, 12kDa
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
GAB2 GRB2-associated binding protein 2
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GHRL ghrelin/obestatin prepropeptide
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GRM1 glutamate receptor, metabotropic 1
GSK3B glycogen synthase kinase 3 beta
GSTA4 glutathione S-transferase alpha 4
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular)
HSPB8 heat shock 22kDa protein 8
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
ICAM1 intercellular adhesion molecule 1
ICMT isoprenylcysteine carboxyl methyltransferase
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL17RA interleukin 17 receptor A
IL1B interleukin 1, beta
IL23R interleukin 23 receptor
IL32 interleukin 32
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
IRF1 interferon regulatory factor 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAG1 jagged 1
JAK2 Janus kinase 2
JUN jun proto-oncogene
KDR kinase insert domain receptor
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF4 Kruppel-like factor 4 (gut)
LAT linker for activation of T cells
LEP leptin
LEPR leptin receptor
LPAR1 lysophosphatidic acid receptor 1
LRP6 low density lipoprotein receptor-related protein 6
LY96 lymphocyte antigen 96
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAGT1 magnesium transporter 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP4 microtubule-associated protein 4
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MIR134 microRNA 134
MIR146A microRNA 146a
MIR27A microRNA 27a
MIRLET7A1 microRNA let-7a-1
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NANOG Nanog homeobox
NDRG1 N-myc downstream regulated 1
NF2 neurofibromin 2 (merlin)
NFE2L2 nuclear factor, erythroid 2-like 2
NRG1 neuregulin 1
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
PARK2 parkin RBR E3 ubiquitin protein ligase
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLAT plasminogen activator, tissue
PLK1 polo-like kinase 1
POMC proopiomelanocortin
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRKCD protein kinase C, delta
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKG1 protein kinase, cGMP-dependent, type I
PRLR prolactin receptor
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPRC protein tyrosine phosphatase, receptor type, C
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
S1PR3 sphingosine-1-phosphate receptor 3
SFTPA1 surfactant protein A1
SIRT6 sirtuin 6
SIRT7 sirtuin 7
SLAMF6 SLAM family member 6
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC30A2 solute carrier family 30 (zinc transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD7 SMAD family member 7
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK25 serine/threonine kinase 25
TERT telomerase reverse transcriptase
TGFB2 transforming growth factor, beta 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMEM207 transmembrane protein 207
TNF tumor necrosis factor
TP53 tumor protein p53
TRAF2 TNF receptor-associated factor 2
TRAF4 TNF receptor-associated factor 4
TXN thioredoxin
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WWOX WW domain containing oxidoreductase
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein