autocrine Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

398 genes co-occuring with the biological term autocrine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADAM17 ADAM metallopeptidase domain 17
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIF1 allograft inflammatory factor 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANGPT1 angiopoietin 1
ANXA2 annexin A2
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
AREG amphiregulin
ASIC1 acid sensing (proton gated) ion channel 1
AXL AXL receptor tyrosine kinase
AZU1 azurocidin 1
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
BTC betacellulin
CALCRL calcitonin receptor-like
CASR calcium-sensing receptor
CCK cholecystokinin
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL22 chemokine (C-C motif) ligand 22
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR4 chemokine (C-C motif) receptor 4
CCR7 chemokine (C-C motif) receptor 7
CD1D CD1d molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD47 CD47 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CFLAR CASP8 and FADD-like apoptosis regulator
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHIA chitinase, acidic
CHRM3 cholinergic receptor, muscarinic 3
CLDN2 claudin 2
CLEC11A C-type lectin domain family 11, member A
CNR1 cannabinoid receptor 1 (brain)
COMP cartilage oligomeric matrix protein
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
CYSLTR2 cysteinyl leukotriene receptor 2
DIABLO diablo, IAP-binding mitochondrial protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP4 dipeptidyl-peptidase 4
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRB endothelin receptor type B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ENG endoglin
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EP300 E1A binding protein p300
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF5 fibroblast growth factor 5
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGL1 fibrinogen-like 1
FIGF c-fos induced growth factor (vascular endothelial growth factor D)
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GAS6 growth arrest-specific 6
GAST gastrin
GATA6 GATA binding protein 6
GCG glucagon
GDF15 growth differentiation factor 15
GDF2 growth differentiation factor 2
GDF9 growth differentiation factor 9
GDNF glial cell derived neurotrophic factor
GFER growth factor, augmenter of liver regeneration
GH1 growth hormone 1
GH2 growth hormone 2
GHR growth hormone receptor
GHRH growth hormone releasing hormone
GHRHR growth hormone releasing hormone receptor
GHRL ghrelin/obestatin prepropeptide
GLI1 GLI family zinc finger 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GNRHR gonadotropin-releasing hormone receptor
GP6 glycoprotein VI (platelet)
GPI glucose-6-phosphate isomerase
GPR143 G protein-coupled receptor 143
GPR182 G protein-coupled receptor 182
GRM1 glutamate receptor, metabotropic 1
GRN granulin
GRPR gastrin-releasing peptide receptor
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAS2 hyaluronan synthase 2
HBEGF heparin-binding EGF-like growth factor
HCRT hypocretin (orexin) neuropeptide precursor
HDC histidine decarboxylase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HOTAIR HOX transcript antisense RNA
HOXA10 homeobox A10
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSP90AA2P heat shock protein 90kDa alpha (cytosolic), class A member 2, pseudogene
HSPA4L heat shock 70kDa protein 4-like
HSPA9 heat shock 70kDa protein 9 (mortalin)
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGHE immunoglobulin heavy constant epsilon
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17C interleukin 17C
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL18RAP interleukin 18 receptor accessory protein
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R1 interleukin 1 receptor, type I
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL24 interleukin 24
IL27 interleukin 27
IL3 interleukin 3
IL32 interleukin 32
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
INHBA inhibin, beta A
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INS insulin
ISG15 ISG15 ubiquitin-like modifier
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA6 integrin, alpha 6
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB5 integrin, beta 5
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUP junction plakoglobin
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLK3 kallikrein-related peptidase 3
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KNG1 kininogen 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMA5 laminin, alpha 5
LEP leptin
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX2 LIM homeobox 2
LIF leukemia inhibitory factor
LOC402192 chloride channel, nucleotide-sensitive, 1A pseudogene
LRP1 low density lipoprotein receptor-related protein 1
LTBP3 latent transforming growth factor beta binding protein 3
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR155 microRNA 155
MIR637 microRNA 637
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MYB v-myb avian myeloblastosis viral oncogene homolog
NDRG2 NDRG family member 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NLRP3 NLR family, pyrin domain containing 3
NMB neuromedin B
NMBR neuromedin B receptor
NMU neuromedin U
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NPY neuropeptide Y
NRG1 neuregulin 1
NRP1 neuropilin 1
NRP2 neuropilin 2
NTN1 netrin 1
NTN3 netrin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTS neurotensin
NTSR1 neurotensin receptor 1 (high affinity)
OSM oncostatin M
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAEP progestagen-associated endometrial protein
PDE3A phosphodiesterase 3A, cGMP-inhibited
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDPN podoplanin
PELP1 proline, glutamate and leucine rich protein 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLG plasminogen
PLXNA1 plexin A1
POSTN periostin, osteoblast specific factor
POU3F2 POU class 3 homeobox 2
PPIA peptidylprolyl isomerase A (cyclophilin A)
PRKCA protein kinase C, alpha
PRL prolactin
PRLR prolactin receptor
PROK2 prokineticin 2
PRSS3 protease, serine, 3
PTEN phosphatase and tensin homolog
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGFR prostaglandin F receptor (FP)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTH1R parathyroid hormone 1 receptor
PTHLH parathyroid hormone-like hormone
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PTTG1 pituitary tumor-transforming 1
RELN reelin
RET ret proto-oncogene
RHOA ras homolog family member A
RHOC ras homolog family member C
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX2 runt-related transcription factor 2
S100A4 S100 calcium binding protein A4
S100P S100 calcium binding protein P
S1PR2 sphingosine-1-phosphate receptor 2
S1PR4 sphingosine-1-phosphate receptor 4
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC1 syndecan 1
SDC4 syndecan 4
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHH sonic hedgehog
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SMAD5 SMAD family member 5
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SORT1 sortilin 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPHK1 sphingosine kinase 1
SPINK1 serine peptidase inhibitor, Kazal type 1
SPP1 secreted phosphoprotein 1
SRGN serglycin
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
ST2 suppression of tumorigenicity 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK11 serine/threonine kinase 11
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TEK TEK tyrosine kinase, endothelial
TERF2IP telomeric repeat binding factor 2, interacting protein
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TYRO3 TYRO3 protein tyrosine kinase
UCN3 urocortin 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIP vasoactive intestinal peptide
VIPR1 vasoactive intestinal peptide receptor 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WLS wntless Wnt ligand secretion mediator
WNT10A wingless-type MMTV integration site family, member 10A
WNT11 wingless-type MMTV integration site family, member 11
WNT5A wingless-type MMTV integration site family, member 5A
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YY1 YY1 transcription factor
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2