| Dataset | GO Biological Process Annotations 2025 |
| Category | structural or functional annotations |
| Type | biological process |
| Description | A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells. (Gene Ontology, GO_0048102) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0048102 |
| Similar Terms | |
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4 genes participating in the autophagic cell death biological process from the curated GO Biological Process Annotations 2025 dataset.
