axenfeld-rieger syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An autosomal dominant disease characterized by abnormalities of the front part of the eye, the anterior segment. (Human Disease Ontology, DOID_14686)
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Genes

57 genes co-occuring with the disease axenfeld-rieger syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PITX2 paired-like homeodomain 2 2.96593
FOXC1 forkhead box C1 2.72842
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 1.30314
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 1.22952
SMYD1 SET and MYND domain containing 1 1.17808
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 1.16606
HMGN2 high mobility group nucleosomal binding domain 2 1.13078
HSPA6 heat shock 70kDa protein 6 (HSP70B') 1.08034
FOXP2 forkhead box P2 0.994439
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.983057
SH3PXD2B SH3 and PX domains 2B 0.980952
UGT8 UDP glycosyltransferase 8 0.963309
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.947852
PAWR PRKC, apoptosis, WT1, regulator 0.926692
FOXF2 forkhead box F2 0.917199
NEUROG2 neurogenin 2 0.916375
MEIS2 Meis homeobox 2 0.914727
ELSPBP1 epididymal sperm binding protein 1 0.911845
FOXQ1 forkhead box Q1 0.838885
CBX5 chromobox homolog 5 0.829869
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.806488
PAX6 paired box 6 0.772479
KERA keratocan 0.76431
FOXJ1 forkhead box J1 0.763902
MNX1 motor neuron and pancreas homeobox 1 0.748017
POU1F1 POU class 1 homeobox 1 0.747204
ATOH1 atonal homolog 1 (Drosophila) 0.709975
MEF2A myocyte enhancer factor 2A 0.698313
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.687891
DVL1 dishevelled segment polarity protein 1 0.567997
CLOCK clock circadian regulator 0.567997
FZD1 frizzled class receptor 1 0.554791
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 0.548195
MYF5 myogenic factor 5 0.53657
FZD4 frizzled class receptor 4 0.526904
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.516879
MAP2K3 mitogen-activated protein kinase kinase 3 0.498467
FGF10 fibroblast growth factor 10 0.484744
AMELY amelogenin, Y-linked 0.446182
NDP Norrie disease (pseudoglioma) 0.433021
PITX1 paired-like homeodomain 1 0.429642
AMELX amelogenin, X-linked 0.415024
PBX1 pre-B-cell leukemia homeobox 1 0.383337
ELAVL1 ELAV like RNA binding protein 1 0.37555
FOXL2 forkhead box L2 0.360764
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.28831
NEUROD1 neuronal differentiation 1 0.248554
BMP7 bone morphogenetic protein 7 0.247852
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.227297
IRF6 interferon regulatory factor 6 0.222822
MYOG myogenin (myogenic factor 4) 0.212945
COL1A1 collagen, type I, alpha 1 0.198709
PRL prolactin 0.186811
FOXO1 forkhead box O1 0.183541
MYOD1 myogenic differentiation 1 0.171785
FLNA filamin A, alpha 0.162707
ERBB3 erb-b2 receptor tyrosine kinase 3 0.160203