axon Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. (Gene Ontology, GO_0030424)
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Genes

270 proteins localized to the axon cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
TPGS1 tubulin polyglutamylase complex subunit 1 0.663342
LRRTM1 leucine rich repeat transmembrane neuronal 1 0.663342
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.663342
HTT huntingtin 0.663342
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.663342
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 0.663342
NEFH neurofilament, heavy polypeptide 0.663342
NEFL neurofilament, light polypeptide 0.663342
NEFM neurofilament, medium polypeptide 0.663342
HEPACAM hepatic and glial cell adhesion molecule 0.663342
SNAP25 synaptosomal-associated protein, 25kDa 0.663342
LRRK2 leucine-rich repeat kinase 2 0.663342
CNTN4 contactin 4 0.663342
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.663342
DST dystonin 0.663342
CCSAP centriole, cilia and spindle-associated protein 0.663342
CABP4 calcium binding protein 4 0.663342
GHRL ghrelin/obestatin prepropeptide 0.663342
MAPT microtubule-associated protein tau 0.663342
PPT1 palmitoyl-protein thioesterase 1 0.663342
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.663342
KIF13B kinesin family member 13B 0.663342
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide 0.663342
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.237908
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.237908
GPER1 G protein-coupled estrogen receptor 1 0.237908
IGHMBP2 immunoglobulin mu binding protein 2 0.237908
ERMN ermin, ERM-like protein 0.237908
TGFB2 transforming growth factor, beta 2 0.237908
PRSS12 protease, serine, 12 (neurotrypsin, motopsin) 0.237908
BIN1 bridging integrator 1 0.237908
APP amyloid beta (A4) precursor protein 0.237908
SACS sacsin molecular chaperone 0.237908
CDK5 cyclin-dependent kinase 5 0.237908
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.237908
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.237908
HDAC6 histone deacetylase 6 0.237908
FGF13 fibroblast growth factor 13 0.237908
INA internexin neuronal intermediate filament protein, alpha 0.237908
NCMAP noncompact myelin associated protein 0.237908
EPHB2 EPH receptor B2 0.237908
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.237908
DSCAM Down syndrome cell adhesion molecule 0.237908
DAB2IP DAB2 interacting protein 0.237908
SCN2A sodium channel, voltage gated, type II alpha subunit 0.237908
GRM7 glutamate receptor, metabotropic 7 0.237908
SIRT2 sirtuin 2 0.237908
CNTNAP2 contactin associated protein-like 2 0.237908
ZFYVE27 zinc finger, FYVE domain containing 27 0.237908
NF1 neurofibromin 1 0.237908
RNF6 ring finger protein (C3H2C3 type) 6 0.237908
DTNBP1 dystrobrevin binding protein 1 0.237908
NFIB nuclear factor I/B 0.237908
GRIK3 glutamate receptor, ionotropic, kainate 3 0.237908
AAK1 AP2 associated kinase 1 0.237908
PTPRO protein tyrosine phosphatase, receptor type, O 0.237908
MME membrane metallo-endopeptidase 0.237908
PARD3 par-3 family cell polarity regulator 0.237908
SRCIN1 SRC kinase signaling inhibitor 1 0.237908
CRHBP corticotropin releasing hormone binding protein 0.237908
RAB5A RAB5A, member RAS oncogene family 0.237908
ATCAY ataxia, cerebellar, Cayman type 0.237908
DOCK7 dedicator of cytokinesis 7 0.237908
CALB1 calbindin 1, 28kDa 0.237908
EPHA4 EPH receptor A4 0.237908
FKBP4 FK506 binding protein 4, 59kDa 0.237908
ZPR1 ZPR1 zinc finger 0.237908
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.237908
GPM6A glycoprotein M6A 0.237908
ADGRL1 adhesion G protein-coupled receptor L1 0.237908
IQGAP1 IQ motif containing GTPase activating protein 1 0.237908
SLC38A7 solute carrier family 38, member 7 0.237908
PINK1 PTEN induced putative kinase 1 0.237908
CCK cholecystokinin 0.237908
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.237908
STAT1 signal transducer and activator of transcription 1, 91kDa 0.237908
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.098109
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.098109
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.098109
DLG4 discs, large homolog 4 (Drosophila) 0.098109
COBL cordon-bleu WH2 repeat protein 0.098109
PSEN1 presenilin 1 0.098109
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.098109
SCN1B sodium channel, voltage gated, type I beta subunit 0.098109
CNTN2 contactin 2 (axonal) 0.098109
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.098109
NRCAM neuronal cell adhesion molecule 0.098109
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.098109
GHRH growth hormone releasing hormone 0.098109
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.098109
NRP1 neuropilin 1 0.098109
DIXDC1 DIX domain containing 1 0.098109
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.098109
PSEN2 presenilin 2 0.098109
UHMK1 U2AF homology motif (UHM) kinase 1 0.098109
ACHE acetylcholinesterase (Yt blood group) 0.098109
RAB3A RAB3A, member RAS oncogene family 0.098109
NFASC neurofascin 0.098109
DVL1 dishevelled segment polarity protein 1 0.098109
MTMR2 myotubularin related protein 2 0.098109
FZD3 frizzled class receptor 3 0.098109
EPB41L3 erythrocyte membrane protein band 4.1-like 3 0.098109
SPTBN4 spectrin, beta, non-erythrocytic 4 0.098109
UNC13B unc-13 homolog B (C. elegans) 0.098109
CNTNAP1 contactin associated protein 1 0.098109
TBC1D24 TBC1 domain family, member 24 0.098109
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.098109
LDLRAP1 low density lipoprotein receptor adaptor protein 1 0.098109
SPTBN1 spectrin, beta, non-erythrocytic 1 0.098109
NRXN1 neurexin 1 0.098109
DRD2 dopamine receptor D2 0.098109
UCN3 urocortin 3 0.03318
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.03318
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 0.03318
SEPT5 septin 5 0.03318
BACE1 beta-site APP-cleaving enzyme 1 0.03318
ALDOC aldolase C, fructose-bisphosphate 0.03318
DICER1 dicer 1, ribonuclease type III 0.03318
CADM2 cell adhesion molecule 2 0.03318
CADM1 cell adhesion molecule 1 0.03318
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans) 0.03318
UNC13A unc-13 homolog A (C. elegans) 0.03318
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) 0.03318
HOMER1 homer scaffolding protein 1 0.03318
KATNB1 katanin p80 (WD repeat containing) subunit B 1 0.03318
OPRD1 opioid receptor, delta 1 0.03318
NRTN neurturin 0.03318
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.03318
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.03318
TNK2 tyrosine kinase, non-receptor, 2 0.03318
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.03318
CLDN5 claudin 5 0.03318
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.03318
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.03318
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.03318
MAG myelin associated glycoprotein 0.03318
SCN10A sodium channel, voltage gated, type X alpha subunit 0.03318
CALCA calcitonin-related polypeptide alpha 0.03318
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.03318
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.03318
NPFF neuropeptide FF-amide peptide precursor 0.03318
MYH14 myosin, heavy chain 14, non-muscle 0.03318
MYO6 myosin VI 0.03318
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.03318
PRKCZ protein kinase C, zeta 0.03318
ILK integrin-linked kinase 0.03318
L1CAM L1 cell adhesion molecule 0.03318
MYH10 myosin, heavy chain 10, non-muscle 0.03318
RAB11B RAB11B, member RAS oncogene family 0.03318
RAB11A RAB11A, member RAS oncogene family 0.03318
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.03318
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.03318
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.03318
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.03318
UCN urocortin 0.03318
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.03318
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.03318
AATK apoptosis-associated tyrosine kinase 0.03318
SEPT6 septin 6 0.03318
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.03318
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.03318
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.03318
CPNE6 copine VI (neuronal) 0.03318
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.03318
PTPRK protein tyrosine phosphatase, receptor type, K 0.03318
PTK2B protein tyrosine kinase 2 beta 0.03318
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.03318
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 0.03318
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.03318
CDH8 cadherin 8, type 2 0.03318
PALM paralemmin 0.03318
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.03318
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.03318
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.03318
TAC1 tachykinin, precursor 1 0.03318
EEA1 early endosome antigen 1 0.03318
SCN11A sodium channel, voltage gated, type XI alpha subunit 0.03318
MBP myelin basic protein 0.03318
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.03318
DRD4 dopamine receptor D4 0.03318
ADORA1 adenosine A1 receptor 0.03318
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.03318
RGS10 regulator of G-protein signaling 10 0.03318
LPAR3 lysophosphatidic acid receptor 3 0.03318
CANX calnexin 0.03318
TMEM57 transmembrane protein 57 0.03318
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.03318
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.03318
AURKA aurora kinase A 0.03318
LRRC4B leucine rich repeat containing 4B 0.03318
APC adenomatous polyposis coli 0.03318
NOV nephroblastoma overexpressed 0.03318
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.03318
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.03318
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.03318
ADCY10 adenylate cyclase 10 (soluble) 0.03318
ADCY9 adenylate cyclase 9 0.03318
NDEL1 nudE neurodevelopment protein 1-like 1 0.03318
BOC BOC cell adhesion associated, oncogene regulated 0.03318
CNGB1 cyclic nucleotide gated channel beta 1 0.03318
FKBP15 FK506 binding protein 15, 133kDa 0.03318
ADRA2C adrenoceptor alpha 2C 0.03318
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.03318
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.03318
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.03318
PFN2 profilin 2 0.03318
DCC DCC netrin 1 receptor 0.03318
SCN1A sodium channel, voltage gated, type I alpha subunit 0.03318
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.03318
SNCB synuclein, beta 0.03318
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.03318
PRPH peripherin 0.03318
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.03318
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.03318
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.03318
TH tyrosine hydroxylase 0.03318
NRP2 neuropilin 2 0.03318
GLUL glutamate-ammonia ligase 0.03318
PTCH1 patched 1 0.03318
DLG2 discs, large homolog 2 (Drosophila) 0.03318
TGFB1 transforming growth factor, beta 1 0.03318
SPHK1 sphingosine kinase 1 0.03318
GAP43 growth associated protein 43 0.03318
LUZP6 leucine zipper protein 6 0.03318
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.03318
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 0.03318
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.03318
EPHB1 EPH receptor B1 0.03318
ANK1 ankyrin 1, erythrocytic 0.03318
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.03318
PVALB parvalbumin 0.03318
DPYSL2 dihydropyrimidinase-like 2 0.03318
MYO1D myosin ID 0.03318
NMU neuromedin U 0.03318
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.03318
CA2 carbonic anhydrase II 0.03318
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.03318
BSN bassoon presynaptic cytomatrix protein 0.03318
ALCAM activated leukocyte cell adhesion molecule 0.03318
KCNIP3 Kv channel interacting protein 3, calsenilin 0.03318
CRH corticotropin releasing hormone 0.03318
DTNA dystrobrevin, alpha 0.03318
TPX2 TPX2, microtubule-associated 0.03318
OXT oxytocin/neurophysin I prepropeptide 0.03318
GRM3 glutamate receptor, metabotropic 3 0.03318
GRM2 glutamate receptor, metabotropic 2 0.03318
DLG1 discs, large homolog 1 (Drosophila) 0.03318
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3 0.03318
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.03318
NCAM2 neural cell adhesion molecule 2 0.03318
CHAT choline O-acetyltransferase 0.03318
AQP1 aquaporin 1 (Colton blood group) 0.03318
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.03318
CHRM1 cholinergic receptor, muscarinic 1 0.03318
CHRM3 cholinergic receptor, muscarinic 3 0.03318
ACTB actin, beta 0.03318
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 0.03318
GRIK4 glutamate receptor, ionotropic, kainate 4 0.03318
GRIK5 glutamate receptor, ionotropic, kainate 5 0.03318
GRM4 glutamate receptor, metabotropic 4 0.03318
NCS1 neuronal calcium sensor 1 0.03318
RHOA ras homolog family member A 0.03318
MAF1 MAF1 homolog (S. cerevisiae) 0.03318
OPHN1 oligophrenin 1 0.03318
IRX3 iroquois homeobox 3 0.03318
NRG1 neuregulin 1 0.03318
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.03318
NTNG2 netrin G2 0.03318
ADAM21 ADAM metallopeptidase domain 21 0.03318
KIAA1598 0.03318