axonal growth cone Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The migrating motile tip of a growing nerve cell axon. (Gene Ontology, GO_0044295)
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Genes

140 proteins co-occuring with the axonal growth cone cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 1.59952
NTN1 netrin 1 1.58968
PLXNB1 plexin B1 1.34501
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 1.3325
MAG myelin associated glycoprotein 1.24184
L1CAM L1 cell adhesion molecule 1.1988
NRP1 neuropilin 1 1.11837
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 1.09543
OMG oligodendrocyte myelin glycoprotein 1.04632
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.946382
UNC5C unc-5 homolog C (C. elegans) 0.936905
UNC5B unc-5 homolog B (C. elegans) 0.935016
DPYSL2 dihydropyrimidinase-like 2 0.915309
INPP5J inositol polyphosphate-5-phosphatase J 0.886089
RTN4R reticulon 4 receptor 0.873186
PLXND1 plexin D1 0.854339
RAX2 retina and anterior neural fold homeobox 2 0.838728
UNC5A unc-5 homolog A (C. elegans) 0.82863
PTPRS protein tyrosine phosphatase, receptor type, S 0.815781
GAP43 growth associated protein 43 0.803855
PLXNA1 plexin A1 0.802938
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.795145
NTN3 netrin 3 0.756799
NEO1 neogenin 1 0.756345
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F 0.708808
NRCAM neuronal cell adhesion molecule 0.707482
NGF nerve growth factor (beta polypeptide) 0.658619
BDNF brain-derived neurotrophic factor 0.650869
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.647433
NTNG1 netrin G1 0.646145
ABLIM1 actin binding LIM protein 1 0.612048
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.588037
DSCAM Down syndrome cell adhesion molecule 0.585105
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.578416
DCC DCC netrin 1 receptor 0.572162
CDK5 cyclin-dependent kinase 5 0.563847
NRP2 neuropilin 2 0.563432
LRRC4C leucine rich repeat containing 4C 0.5597
RNF6 ring finger protein (C3H2C3 type) 6 0.557629
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.554732
FGF13 fibroblast growth factor 13 0.547297
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.541529
FGFR2 fibroblast growth factor receptor 2 0.52675
NTNG2 netrin G2 0.524704
DLL4 delta-like 4 (Drosophila) 0.523067
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.519389
RTN4 reticulon 4 0.518573
NPAT nuclear protein, ataxia-telangiectasia locus 0.51164
RRAS related RAS viral (r-ras) oncogene homolog 0.510826
PALLD palladin, cytoskeletal associated protein 0.49418
MAP1B microtubule-associated protein 1B 0.484079
MAPRE3 microtubule-associated protein, RP/EB family, member 3 0.477233
OTX1 orthodenticle homeobox 1 0.477233
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.476027
ELSPBP1 epididymal sperm binding protein 1 0.476027
PLXNA3 plexin A3 0.475625
KANK1 KN motif and ankyrin repeat domains 1 0.472011
SMN2 survival of motor neuron 2, centromeric 0.459602
PKN1 protein kinase N1 0.446862
ACTB actin, beta 0.444878
KIF21A kinesin family member 21A 0.442896
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.433012
NCAM1 neural cell adhesion molecule 1 0.428678
LRRC16A leucine rich repeat containing 16A 0.422782
FZD5 frizzled class receptor 5 0.419644
ACTG1 actin gamma 1 0.418077
GRIP1 glutamate receptor interacting protein 1 0.408309
GPS2 G protein pathway suppressor 2 0.408309
GSK3B glycogen synthase kinase 3 beta 0.400527
EFNA5 ephrin-A5 0.399363
ARID1B AT rich interactive domain 1B (SWI1-like) 0.397423
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.392388
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila) 0.385436
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.380814
SYN1 synapsin I 0.374666
ARHGAP4 Rho GTPase activating protein 4 0.372749
FZD3 frizzled class receptor 3 0.371982
MAP2 microtubule-associated protein 2 0.361277
INPP5A inositol polyphosphate-5-phosphatase, 40kDa 0.35899
EPHA7 EPH receptor A7 0.357086
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.356324
SMN1 survival of motor neuron 1, telomeric 0.351382
PFN2 profilin 2 0.339261
DBN1 drebrin 1 0.327956
STK25 serine/threonine kinase 25 0.316708
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.31596
KLK6 kallikrein-related peptidase 6 0.31596
CRMP1 collapsin response mediator protein 1 0.315586
PFN4 profilin family, member 4 0.305515
DAAM1 dishevelled associated activator of morphogenesis 1 0.302168
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.287721
ALOX12 arachidonate 12-lipoxygenase 0.277038
PFN1 profilin 1 0.275569
EFNA2 ephrin-A2 0.274468
DTNBP1 dystrobrevin binding protein 1 0.266408
NCK1 NCK adaptor protein 1 0.266042
FUS FUS RNA binding protein 0.26166
KLF6 Kruppel-like factor 6 0.259473
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.251839
CAPN2 calpain 2, (m/II) large subunit 0.250389
RDX radixin 0.247492
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.244601
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.241716
RAP1GAP RAP1 GTPase activating protein 0.238119
ATL1 atlastin GTPase 1 0.234533
VANGL2 VANGL planar cell polarity protein 2 0.234174
ALCAM activated leukocyte cell adhesion molecule 0.230601
SNAI2 snail family zinc finger 2 0.229176
NRTN neurturin 0.228464
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 0.227041
KIF2A kinesin heavy chain member 2A 0.226686
GIPC1 GIPC PDZ domain containing family, member 1 0.22385
METTL13 methyltransferase like 13 0.218914
MSN moesin 0.21716
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.215412
EFNA1 ephrin-A1 0.21124
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.205059
CDH13 cadherin 13 0.203361
USP9X ubiquitin specific peptidase 9, X-linked 0.199659
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 0.19733
SYP synaptophysin 0.196669
RHOQ ras homolog family member Q 0.195353
SNAP25 synaptosomal-associated protein, 25kDa 0.194045
BCAN brevican 0.190495
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.189857
NTF3 neurotrophin 3 0.18859
VAV2 vav 2 guanine nucleotide exchange factor 0.18516
WASH7P WAS protein family homolog 7 pseudogene 0.184241
NCAN neurocan 0.183328
GLE1 GLE1 RNA export mediator 0.182723
WASH6P WAS protein family homolog 6 pseudogene 0.181524
WASH1 WAS protein family homolog 1 0.179752
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.179459
CDC42 cell division cycle 42 0.174087
MAPT microtubule-associated protein tau 0.169604
PTEN phosphatase and tensin homolog 0.168847
EZR ezrin 0.168598
PROX1 prospero homeobox 1 0.168598
EXOC7 exocyst complex component 7 0.159074
TECTA tectorin alpha 0.157218